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Volume 7 Issue 10, October 2023

In-ear monitoring of brain states and of lactate in sweat

This issue highlights advances in the application of wearable, ingestible or implantable bioelectronic devices for the monitoring of health status, disease progression or the effectiveness of treatment. It also includes electronic scaffolds for tracking the migration of brain cells after injury, and implants that facilitate closed-loop neuromodulation in small animals.

The cover illustrates the integration, on an earbud, of sensors for brain activity (via electroencephalography, electrooculography and electrodermal activity) and of lactate levels (electrochemically, in sweat).

See Xu et al.

Image: Yuchen Xu, University of California San Diego. Cover design: Alex Wing.

Editorial

  • The management of health and of disease conditions will eventually be supported by ever more integrated and less conspicuous wireless bioelectronic devices designed to continuously monitor multiple biomarkers.

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News & Views

  • An integrated array of sensors can be seamlessly incorporated into a generic earphone, for the simultaneous monitoring of electrophysiological and electrochemical signals.

    • Xiao Xiao
    • Yihao Zhou
    • Jun Chen

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  • Metrics of cardiovascular health, such as vascular resistance and cardiac output, can be monitored via synchronized sensors for electrocardiography and multispectral photoplethysmography that are placed on the chest and peripherally.

    • Justin R. Estepp

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    News & Views
  • During radiotherapy, an X-ray dosimeter in the gastrointestinal tract allows for the real-time monitoring of the absolute absorbed radiation dose alongside changes in pH and temperature, as shown in rabbits.

    • Louis Archambault

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Research

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