Volume 90 Issue 12, December 2010

Special Issue – Hepatic and Pancreatic Systems

The cover shows bioimaging of mouse liver oxidative stress after partial hepatectomy. roGFP (reduction/oxidation-sensitive green fluorescent protein) allows real-time visualization of the oxidation/reduction potentials of the organ. roGFP was adenovirally transducted to mouse liver prior to partial hepatectomy. Light emission from redox-sensitive GFP (roGFP) from remnant liver lobes was directly measured and imaged from the exposed liver surface after partial hepatectomy. For more information see the paper by Haga et al, on page 1718