Focus on metals
In this issue - pv
doi:10.1038/nchembio0308-v
Focus
Focus on Metals
- Focus issue:
- March 2008 Volume 4, No 3
In this issue, we highlight important recent advances in understanding both the chemistry and biology of metals in biological systems. We also feature new tools and approaches that can be used to gain a better understanding of the roles that metal ions play in cells and in whole organisms. We hope this collection of articles highlights the excitement of the 'chemical biology' of metals.
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Editorial
Focus on metals
Metals in chemical biology - p143
doi:10.1038/nchembio0308-143
As scientists move towards a more comprehensive understanding of the role of metals in biology, bioinorganic chemistry will be an increasingly important component of chemical biology.
Full Text - Metals in chemical biology | PDF (220 KB) - Metals in chemical biology
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Commentaries
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Assembling the pieces - pp145 - 147
Dennis J Thiele & Jonathan D Gitlin
doi:10.1038/nchembio0308-145
Abstract - Assembling the pieces | Full Text - Assembling the pieces | PDF (260 KB) - Assembling the pieces
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A place for thioether chemistry in cellular copper ion recognition and trafficking - pp148 - 151
Anna V Davis & Thomas V O'Halloran
doi:10.1038/nchembio0308-148
Abstract - A place for thioether chemistry in cellular copper ion recognition and trafficking | Full Text - A place for thioether chemistry in cellular copper ion recognition and trafficking | PDF (525 KB) - A place for thioether chemistry in cellular copper ion recognition and trafficking
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Expanding chemical biology of 2-oxoglutarate oxygenases - pp152 - 156
Christoph Loenarz & Christopher J Schofield
doi:10.1038/nchembio0308-152
Abstract - Expanding chemical biology of 2-oxoglutarate oxygenases | Full Text - Expanding chemical biology of 2-oxoglutarate oxygenases | PDF (478 KB) - Expanding chemical biology of 2-oxoglutarate oxygenases
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Elements
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Ivano Bertini - p157
Joanne Kotz
doi:10.1038/nchembio0308-157
Building on his contributions to NMR methodologies for studying metalloproteins, Bertini has been instrumental in bringing together inorganic chemists and biologists interested in metals in biology.
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Top of pageReviews
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Synthetic fluorescent sensors for studying the cell biology of metals - pp168 - 175
Dylan W Domaille, Emily L Que & Christopher J Chang
doi:10.1038/nchembio.69
Abstract - Synthetic fluorescent sensors for studying the cell biology of metals | Full Text - Synthetic fluorescent sensors for studying the cell biology of metals | PDF (635 KB) - Synthetic fluorescent sensors for studying the cell biology of metals
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Mechanisms for copper acquisition, distribution and regulation - pp176 - 185
Byung-Eun Kim, Tracy Nevitt & Dennis J Thiele
doi:10.1038/nchembio.72
Abstract - Mechanisms for copper acquisition, distribution and regulation | Full Text - Mechanisms for copper acquisition, distribution and regulation | PDF (6,022 KB) - Mechanisms for copper acquisition, distribution and regulation
Focus on metals
Versatility of biological non-heme Fe(II) centers in oxygen activation reactions - pp186 - 193
Elena G Kovaleva & John D Lipscomb
doi:10.1038/nchembio.71
Abstract - Versatility of biological non-heme Fe(II) centers in oxygen activation reactions | Full Text - Versatility of biological non-heme Fe(II) centers in oxygen activation reactions | PDF (637 KB) - Versatility of biological non-heme Fe(II) centers in oxygen activation reactions
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