Hydroxide is the most abundant anion in alkaline solutions, but its impact on alkaline water electrolysis remains unclear. Herein, the authors report a biaxial strain induced OH engineer on MoSe₂ to accelerate alkaline hydrogen evolution by modifying the water dissociation.

Point-defect metamaterials have the property of concentrating vibration energy at the defect location. We design an environmental monitoring node based on this property, which can efficiently convert wave kinetic energy into electrical energy for real-time monitoring of the ocean environment.

Dynamic covalent bonding can be useful in preparation of stimuli responsive materials, but this is challenging in the aggregated state. Here, the authors report the development of compounds with photoinduced π-bond cleavage to prepare dynamic covalent bond materials.

Analogue quantum simulators have looser requirements than digital ones, but rigorous results on their usefulness in the noisy case are few. Here, the authors conclude that analogue quantum simulators are robust to errors and can provide superpolynomial to exponential quantum advantage when used to compute relevant many-body observables.

Nanosizing covalent organic frameworks using surfactants provides greatly improved water dispersibility and light-harvesting properties, leading to dramatically enhanced photocatalytic hydrogen production performance. Here the authors observe a reverse concentration-dependent photocatalytic phenomeno, whereby a higher photocatalytic activity is found at a lower catalyst concentration.

Waste lithium-ion batteries and low-density polyethylene plastics present environmental issues. Herein, the authors demonstrate a synergistic pyrolysis approach for efficient and selective lithium extraction and upgrading of transition metal-carbon composites.

Temporarily overshooting the 1.5 °C limit risks triggering climate tipping elements. This study finds that every 0.1 °C of warming increases risk, with a strong acceleration above +2.0 °C. Achieving net-zero emissions by 2100 is crucial to minimise long-term risks.

Hinsley and colleagues explore trends in the global wildlife trade, developing a novel machine-learning approach to analyse patent filing related to important taxa from 1970 to 2020. They found higher per year increases in these taxa compared with background trends, giving insight into how wildlife-related businesses predict, adapt to and create market shifts. These results provide data to underpin proactive wildlife-trade management approaches.

Terrestrial carbon emissions from global expansion of impervious surface area have been long overlooked in global carbon budget assessments. Qiu et al. report that these emissions account for up to 6.0–12.9% of those from human land use change.

Using a three-dimensional ice sheet model, this work demonstrates that more than half of the Holocene surface elevation drop recorded in ice cores from north-central Greenland can be attributed to ice dynamic changes in northeast Greenland following ice-sheet retreat during the last deglaciation.

Batch effects can limit the usefulness of image-based profiling data. Here, authors benchmark ten popular batch correction techniques on a large Cell Painting dataset, evaluating multiple metrics. They identify Harmony and Seurat RPCA as top methods across diverse complex scenarios.

Analysing shotgun proteomics data is challenging due to diverse research questions. Here, authors introduce OmicScope, a computational tool available via both programming language and web platform, designed to analyze and integrate complex omics data from differential proteomics to meta-analysis.

It is common to engineer membrane proteins for cryo-EM analysis. Here, the authors report a cryo-EM structure of an engineered, functional VMAT2 with a non-canonical fold. Caution is advised when interpreting engineered membrane protein structures.

The powdery mildew resistance gene Pm13 was introgressed into wheat from Aegilops longissima. Here, the authors report the cloning of Pm13 and reveal that it encodes a MLKL_NTD domain-containing kinase.

Crocodilians are ambush predators that possess haemoglobin with an allosteric switch between R (high oxygen affinity) and T (low oxygen affinity) forms strongly controlled by bicarbonate ions, a unique evolutionary feature that helps the animal to stay underwater for extended periods of time.

After myocardial infarction, excessive inflammation impairs heart repair, leading to reduced cardiac function. Here, the authors show that treatment with anti-inflammatory immune cells (regulatory T cells) improves cardiac repair by modulating the activity of a specific subset of macrophages in the heart.

In this study, the authors report the small molecule inhibitor EDP-235 as a potent inhibitor of SARS-CoV-2 and show that it is effective against a range of variants and other coronaviruses and that it suppresses virus replication, reduces lung damage, and prevents transmission in small animal models.

Understanding why people hesitated to seek COVID-19 vaccines after they became available can inform public health policies. Here, the authors use search engine data to infer vaccination rates and intentions across the United States, then develop a taxonomy of vaccine concerns and identify the most prevalent apprehensions.

Ventilator-associated pneumonia (VAP) is a nosocomial infection that significantly affects critically ill patients undergoing mechanical ventilation in the Intensive Care Unit (ICU). This review presents the diagnostic challenges associated with VAP in ICU.

Nerve grafts often fail to match the expected shape and size for branched nerve repair. Here, the authors fabricate a sugar painting-inspired individualized multilevel epi-/peri-/endoneurium-mimetic device to achieve efficient regeneration of neural fibers.

Can residents in a community microgrid enjoy greater electricity quotas during blackouts by paying more? Study shows US residents support market-based mechanisms even in life-and-death situations.

Hickel and colleagues find that, in 2021, the economies of the global North net-appropriated 826 billion hours of embodied labour from the global South, across all skill levels and sectors. Unequal exchange is understood to be driven in part by systematic wage inequalities. They find Southern wages are 87-95% lower than Northern wages for work of equal skill. While Southern workers contribute 90% of the labour that powers the world economy, they receive only 21% of global income.

Global future carbon removal efforts could largely be concentrated in Asia. Here, this study shows that multi-gigatonnes expectation of carbon removal could have adverse impact on the energy-land-water system of countries and regions within the continent.

Hydrological risks drive migration more than socioeconomic factors. Vulnerable groups often stay in high-risk areas or migrate nearby. The study reveals an S-shaped migration pattern influenced by settlement resilience and adaptability.

Using satellite observations, communities in the U.S. containing warehouses experience more truck traffic and increased health-harming pollution with a disproportionate number of racial and ethnic minorities living in these communities.