formation of a tumour in the nervous system

Mechanisms specifying cancer cell states and response to therapy in schwannomas

Three articles analyse the molecular features of schwannomas, tumours of the peripheral nervous system that arise from Schwann cells, which normally wrap around and protect nerves.

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  • Highly polarized nuclear spins can supress decoherence of electron spin qubits, but this requires near-unity polarization. Here the authors implement a protocol combining optical excitation and fast carrier tunnelling to achieve nuclear spin polarizations above 95% in GaAs quantum dots on a timescale of 1 minute.

    • Peter Millington-Hotze
    • Harry E. Dyte
    • Evgeny A. Chekhovich
    ArticleOpen Access
  • The Higgs mode in condensed matter physics refers to the oscillations of the amplitude of the order parameter, and single Higgs modes have been studies in various systems. Here the authors report real-space observation of two coupled Higgs modes in a 1D charge density wave phase of CuTe.

    • SeongJin Kwon
    • Hyunjin Jung
    • Han Woong Yeom
    ArticleOpen Access
  • X-ray Free Electron Lasers allow fast structure determination. Here, the authors push the temporal limit of atomic level structure determination to 25 fs, the length of a single pulse, paving the way to the study of fast, non-repeatable processes.

    • Gábor Bortel
    • Miklós Tegze
    • Gyula Faigel
    ArticleOpen Access
  • Exceptional points emerge in systems with loss and gain when loss and gain in the system are balanced. Due to the careful balancing involved, they are highly sensitive to perturbations, making them exceptionally useful for sensors and other devices. Here, Wittrock et al observe a variety of complex dynamics associated with exceptional points in coupled spintronic nano-oscillators.

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    • Salvatore Perna
    • Vincent Cros
    ArticleOpen Access

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  • Africa is undergoing a demographic transition1 that has led to significant reductions in the number of individuals living in extreme poverty, and to positive shifts in related health outcomes, across its diverse populations2. Building on these successes requires a consideration of intersecting factors that impact health metrics, which is the focus of the United Nations Sustainable Development Goals3. To support researchers in their efforts towards reaching these goals, Nature Communications, Communications Medicine and Scientific Reports invite submissions of papers that advance our understanding of all aspects of health in Africa.

    EditorialOpen Access
  • The emergence of high-entropy materials has inspired the exploration of novel materials in diverse technologies. In electrochemical energy storage, high-entropy design has shown advantageous impacts on battery materials such as suppressing undesired short-range order, frustrating energy landscape, decreasing volumetric change and reducing the reliance on critical metals. This comment addresses the definition and potential improper use of the term “high entropy” in the context of battery materials design, highlights the unique properties of high-entropy materials in battery applications, and outlines the remaining challenges in the synthesis, characterization, and computational modeling of high-entropy battery materials.

    • Bin Ouyang
    • Yan Zeng
    CommentOpen Access
  • Combining ocean predictions with physiological understanding yields the ability to forecast habitat multiple years into the future for a wide variety of marine organisms. However, several challenges remain before we see the regular production and use of marine habitat forecasts.

    • Mark R. Payne
    CommentOpen Access
  • Innovative pharmacogenomic approaches (genetic variation related to medication response) are needed to reduce disease and disparities in Indigenous communities. We support community-based pharmacogenomics research, inclusive of Indigenous values and priorities, to improve the health and well-being of Indigenous peoples.

    • Katrina G. Claw
    • Casey R. Dorr
    • Erica L. Woodahl
    CommentOpen Access
  • Synthetic optical materials have been recently employed as a powerful platform for the emulation of topological phenomena in wave physics. Topological phases offer exciting opportunities, not only for fundamental physics demonstrations, but also for practical technologies. Yet, their impact has so far been primarily limited to their claimed enhanced robustness. Here, we clarify the role of robustness in topological photonic systems, and we discuss how topological photonics may offer a wider range of important opportunities in science and for practical technologies, discussing emergent and exciting research directions.

    • Alexander B. Khanikaev
    • Andrea Alù
    CommentOpen Access
  • The African continent demonstrated decisive leadership throughout its response to the COVID-19 pandemic, leveraging lessons learned from previous outbreaks and acting quickly to limit the impact of the SARS-CoV-2 virus. We propose a framework to build on these successes that calls for greater collaboration between African leaders, and greater inclusion of African voices in the global health ecosystem.

    • Nicaise Ndembi
    • Aggrey Aluso
    • Jean Kaseya
    CommentOpen Access
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Immunology

Here we select our recent, most exciting articles focusing on both basic and translational immunology, encompassing immune cell development, biology and regulation, host responses to pathogens, immunological disorders such as allergy and autoimmunity, systems immunology, and finally immune therapy.
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