Mangroves

Priority areas to protect mangroves and maximise ecosystem services

Mangroves provide key ecosystem services but are threatened by human activities. Alvise Dabalà et al. identify priority areas that maximise protection of mangrove biodiversity and ecosystem services.

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Latest Research articles

  • Previous work on charge Kondo circuits, in which a spin is formed by two degenerate charge states of a metallic island, has been limited to transport measurements of multi-channel Kondo problems. Piquard et al. use thermodynamic measurements via a charge sensor to study the evolution of a single Kondo impurity.

    • C. Piquard
    • P. Glidic
    • F. Pierre
    ArticleOpen Access
  • Interlayer coupling strength classifies 2D materials into layered and non-layered types. Here authors introduce the concept of quasi-layered domino-structured materials, the interlayer of which have a synergistic blend of vdW forces and covalent bonds.

    • Haihui Lan
    • Luyang Wang
    • Lei Fu
    ArticleOpen Access
  • The fractional quantum Hall state at the filling factor 5/2 has been intensively studied due to its predicted non-Abelian statistics. Petrescu et al. measure the composite fermion effective mass of this state and find that it is several times larger than that in the half-filled lowest Landau level.

    • M. Petrescu
    • Z. Berkson-Korenberg
    • G. Gervais
    ArticleOpen Access

Subjects within Physical sciences

Subjects within Earth and environmental sciences

Subjects within Biological sciences

  • Temporalis muscle thickness is a promising marker of lean muscle mass but has had limited utility due to its unknown normal growth trajectory and lack of standardized measurement. Here, the authors develop an automated deep learning pipeline to accurately measure temporalis muscle thickness from routine brain magnetic resonance imaging.

    • Anna Zapaishchykova
    • Kevin X. Liu
    • Benjamin H. Kann
    ArticleOpen Access
  • Epacadostat is a selective IDO1 inhibitor shown to promote anti-tumor immune responses in preclinical models, however it has failed in a Phase III clinical trial for treating metastatic melanoma. Here the authors design a sphingomyelin-derived nanovesicle system for epacadostat delivery with improved pharmacokinetics and anti-tumor activity when combined with a PD-1 inhibitor in melanoma preclinical models.

    • Zhiren Wang
    • Wenpan Li
    • Jianqin Lu
    ArticleOpen Access
  • Here, Chen et. al. characterize the relationship between the gut microbiota and plasma metabolite changes in the context of ST-elevation myocardial infarction (STEMI), unveiling a role of butyrate-producing bacteria and their ketogenesis in post-STEMI cardiac repair, a finding validated in nonhuman primate and mouse models. They show that butyrate supplementation reduces myocardial infarction severity in mice, underscoring the significance of butyrate-producing bacteria and beta-hydroxybutyrate in improving post-MI outcomes.

    • Hung-Chih Chen
    • Yen-Wen Liu
    • Patrick C. H. Hsieh
    ArticleOpen Access

Subjects within Health sciences

  • Green technologies foster the use of green energy; however, large investment costs hinder adoption. In a large-scale field experiment, the authors show that message framing can promote a serious commitment to solar panels among the broader public.

    • Dominik Bär
    • Stefan Feuerriegel
    • Markus Weinmann
    ArticleOpen Access
  • Over their careers, medicinal chemists develop a gut feeling for what is a promising molecule. Here, the authors use machine learning models to learn this intuition and show that it can be successfully applied in several drug discovery scenarios.

    • Oh-Hyeon Choung
    • Riccardo Vianello
    • José Jiménez-Luna
    ArticleOpen Access
  • Membrane distillation is an emerging desalination technology to obtain freshwater from saline based on low-grade energy. Here the authors report on novel superhydrophobic hierarchical porous membranes with enhanced distillation flux suitable for desalination or wastewater treatment.

    • Youmin Hou
    • Prexa Shah
    • Hans-Jürgen Butt
    ArticleOpen Access

Subjects within Scientific community and society

  • Spatial transcriptomic profiling of cancer has enabled spatial delineation of malignant transcriptional heterogeneity, intercellular communication, and organization of microanatomical structures within the tumor microenvironment. This technical breakthrough paves the way for the development of precision diagnostic methods and targeted therapies.

    • Young Min Park
    • De-Chen Lin
    CommentOpen Access
  • The superspreading that characterized SARS and now COVID-19 can be rapidly quantified; however, its implications for outbreak control were never well understood. Recent studies point to its profound impact on outbreak dynamics and prospects for effective control of a future Disease X. These insights necessitate research into the mechanisms, impact and different modes of superspreading more widely.

    • Bjarke Frost Nielsen
    • Kim Sneppen
    • Lone Simonsen
    CommentOpen Access
  • Machine learning is a powerful tool for the study and design of molecules. Here the authors comment a recent publication in Nature Communications which highlights the challenges of different molecular representations for data-driven property predictions.

    • Ana Laura Dias
    • Latimah Bustillo
    • Tiago Rodrigues
    CommentOpen Access
  • 2D semiconductors have been proposed as a potential option to replace or complement silicon electronics at the nanoscale. Here, the authors discuss the recent progress and remaining challenges that need to be addressed by the academic and industrial research communities towards the commercialization of 2D transistors.

    • Kevin P. O’Brien
    • Carl H. Naylor
    • Uygar Avci
    CommentOpen Access
  • β-Glucocerebrosidase (GCase) mutations lead to glucosylceramide build-up in the lysosome, impacting α-synuclein aggregation and autophagy. Recently, Baden and colleagues found GCase in mitochondria, supporting mitochondrial complex I function and energy metabolism. We believe the newly described role of GCase in the mitochondria will inform new Parkinson’s and Gaucher’s disease therapeutics.

    • Andrés D. Klein
    • Tiago Fleming Outeiro
    CommentOpen Access
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