Lead halide perovskite nanocrystals show bright and colour-pure emission in the visible range, which can be tuned by nanocrystal size and composition. Here authors present the formation mechanisms of anisotropic lead halide perovskite nanocrystals, 1D nanorods and 2D nanoplatelets, by combining in situ X-ray scattering and photoluminescence spectroscopy.

‘Functional adaptation after local mechanical stimulation is ubiquitous in nature but remains elusive in artificial systems. Here, the authors describe metamaterial hydrogels to sense mechanical stimuli with sharp force threshold, transmit this information and induce mechanical strengthening by growing nanofibril networks or soft robotic actuation through competitive swelling.

The development of hydrogel composites with enhanced moisture-capturing properties is hindered by our limited understanding behind their moisture-capture properties. Here, the authors develop and validate a theoretical description that bridges this knowledge gap for a wide range of synthesized and characterized hydrogel-salt composites.

Grain alignment and polarization engineering were simultaneously utilized to enhance the energy storage performance of Na_1/2Bi_1/2TiO₃-based multilayer ceramic capacitors, leading to an energy density of 15.7 J·cm⁻³ and energy efficiency over 95%.

The authors demonstrate a method for controlling the time-frequency distribution of electromagnetic waves, enabling real-time manipulation. Using standard telecom components, it enables GHz bandwidth, nanosecond programmability, and MHz-level resolution.

Surface water neodymium isotopes and rare earth element compositions reveal a marked impact from the January 2022 Hunga Tonga-Hunga Ha’apai eruption in the western South Pacific, with released trace metals potentially stimulating biological responses.

Titanium concentrations in zircon crystals reveal a link between the world’s largest copper resources and magmas with very high-water contents.

Migrating earthquake sequences from a wide range of tectonic contexts exhibit two distinct behaviors. One is linked to slow slip and characterized by elevated migration velocities and moments, and the other is related to fluid-induced processes, with lower velocities and moments.

The study presents data from moorings in the Challenger Deep, the deepest known hadal trench in the world, showing a three-layer circulation structure, modulated by deep-water intrusion, topography and turbulent mixing.

When mantle plumes are coupled to spreading ridges, they can act as an anchor and impede spreading ridge migration but if the plume weakens, it can de-anchor from the ridge and facilitate rapid ridge migration.

The clinical outcomes of esophageal squamous cell carcinoma (ESCC) remain poor, and thus it remains critical to find prognostic molecular markers. Here, the authors identify prognostic ESCC subtypes based on bulk and single-cell RNA-seq combined with histology AI in samples from patients with more than four years of follow-up, and find markers associated with immune evasion.

DICER is a vital enzyme in small RNA production. Here the authors show how bipartite pairing rules and dual YCR motifs guide DICER's activity on precursor microRNAs.

How the S2P family of intramembrane metalloproteases engage substrates has remained unclear. Here, the authors reveal cryo-EM structures showing beta-sheet augmentation as a key factor in substrate binding, linking this mechanism to all four classes of intramembrane proteases.

Neurogenic bladder often occurs after pelvic ganglia injury. Here, the authors designed a fiber-enhanced tissue bandage for injured pelvic ganglia that facilitates the delivery of growth factors essential for ganglia healing.

Ubiquitination factors play crucial roles in DNA repair. The authors show that deubiquitinase OTUD5 facilitates ATM-dependent DNA damage signalling via the UBR5-ATMIN axis. OTUD5 loss results in DNA repair defects at heterochromatin and deprotected telomeres due to insufficient KAP1^S824 phosphorylation.

The mechanisms connecting intraocular pressure to glaucoma remain unclear. Here, the authors use GWAS by subtraction to reveal intraocular pressure-independent aspects of glaucoma.

Gene drives have the potential to support malaria control by suppressing vector populations, but their impacts will depend on local ecology and epidemiology. Here, the authors incorporate location-specific data to model how gene drives could perform in sixteen diverse African settings.

Gain of function mutant CaV1.2 channels drive life-threatening hypoglycemia in the multisystem disorder Timothy syndrome, but the underlying mechanisms are unknown. Here the authors show the mutant channels have adverse effects on counterregulatory hormones and CNS control of glucose homeostasis.

Spillover of avian influenza H5N1 from birds to mammals have been increasingly detected, but reports of cases in humans remain limited. Here, the authors find serological evidence of human exposure to influenza H5N1 in Malaysian Borneo, an important stopover site for migratory shorebirds.

Here, the authors profile the gut phageome of individuals recruited into two double-blind randomized trials of Fecal Microbial Transplantation for ulcerative colitis, showing that phage communities are stable in health, dysbiotic in ulcerative colitis, modulated by antibiotics and by fecal transplants, with one Oscillospiraceae phage being associated with disease remission.

Six surveys show substantial public agreement with misinformation about wind farms. Agreement with diverse contrarian claims is best predicted by participants’ worldviews, most notably the tendency to believe conspiracy theories.

Plastic pollution can be dealt with advanced recycling and bio-based production. Best-case scenario would require 22 Mha of sugarcane areas in Brazil to meet the 2050 global biopolyethylene demand. However, this may require ecosystem trade-offs.

Unfairness in AI healthcare models arise from biased correlations between sensitive attributes and disease data. Here, the authors show that the Attribute Neutral Framework reduces these biases and enhances fairness without compromising diagnostic accuracy.

This paper proposes an open-source, impact-based forecast for tropical cyclone population displacement using both cyclone forecasts and population settlements and vulnerabilities. This is applied to Tropical Cyclone Yasa, striking Fiji in 2020.

The study shows that India’s agricultural subsidies have driven significant groundwater depletion by incentivizing overproduction of water-intensive crops like rice and wheat. This impact is evident in both Punjab’s alluvial aquifers and Madhya Pradesh’s hard rock aquifers.