●Centrosome aberrations: cause or consequence of cancer progression? Nigg, E. A. Nature Reviews Cancer November (2002)

●Stem cell medicine encounters the immune system. Bradley, J. A, Bolton, E. M. & Pedersen, R. Nature Reviews Immunology November (2002)

●Ubiquitin and the synapse. Hegde, A. N. & DiAntonio, A. Nature Reviews Neuroscience November (2002)

●Horizon Symposia web site http://www.nature.com/drugdisc/horizon/home.html Nature Reviews Drug Discovery November (2002) The first Horizon Symposium, on protein folding and disease, recently brought together some of the world's top scientists for discussion and debate. The free-access web site contains overviews of the topic, as well as session summaries and introductions to the key questions that were discussed.

●Telomere maintenance and cancer — look, no telomerase. Neumann, A. A. & Reddel, R. R. Nature Reviews Cancer November (2002) Opinion article highlighting the alternative mechanisms to telomerases for lengthening telomeres and the importance of understanding these for successful anti-telomere therapy.

●Finer clock control. Alvarez, J. D. & Sehgal, A. Nature 24 October (2002) A News and Views article that outlines the likely function of two proteins — Dec1 and Dec2 — in the molecular regulation of the circadian clock.

●The cellular and molecular basis of store-operated calcium entry. Gill, D. L. Nature Cell Biology November (2002)

●Retinoid signalling in the development of the central nervous system. Maden, M. Nature Reviews Neuroscience November (2002)

●Pinning a change on p53. Ryan, K. M & Vousden, K. H. Nature 24 October (2002) The finding that Pin1 can phosphorylate, and confer a conformational change on, the tumour suppressor p53, and that this increases its activity, is discussed in this News and Views article.

●The origin and evolution of model organisms. Hedges, S. B. Nature Reviews Genetics November (2002)