A genetic melting pot. Feldman, M. W., Lewontin, R. C. & King, M. -C. Nature 24 July (2003) This Concepts article looks at the definition of race.

Chemical discovery and global gene expression analysis in zebrafish. Pilcher, F. B. et al. Nature Biotechnology September (2003)

Mechanism and regulation of human non-homologous DNA end joining. Lieber, M., Ma, Y., Pannicke, U. & Schwarz, K. Nature Reviews Molecular Cell Biology September (2003)

The trials and tribulations of producing the first genetically engineered drug. Johnson, I. S. Nature Reviews Drug Discovery September (2003)

Safeguards and spurs. Stearns, S. C. Nature 31 July (2003) This News and Views article considers how new work, which shows that most genes in regulatory networks have canalizing (buffering) properties, could influence the way we think about evolution and development.

A tale of tails. Niehrs, C. Nature 24 July (2003) The author of this News and Views article discusses the significance of the discovery of a new 'tail-organizing centre' in early zebrafish embryos.

Chromosome aberrations in solid tumors. Albertson, D. G., Collins, C., McCormick, F. & Gray, J. W. Nature Genetics August (2003) The functional importance of chromosome aberrations and the mechanisms by which they might form during cancer progression are summarized. Clinical advances resulting from studies of chromosome aberrations are also discussed.

Genomic instability, the engine of tumorigenesis? Sieber, O. M., Heinimann, K. & Tomlinson, I. P. M. Nature Reviews Cancer September (2003) This Opinion article discusses the apparently conflicting evidence that genomic instability is a driving force for tumour growth, and whether or not it is the usual initiating event in tumorigenesis.

Imaging in Cell Biology. Nature Cell Biology and Nature Reviews Molecular Cell Biology present a joint supplement that focuses on key advances in imaging techniques that allow us to follow cell-biological events ranging from the dynamics of single molecules in living cells to the development of whole organisms. Until March 2004, supplement articles will be available FREE online at http://www.nature.com/focus/cellbioimaging, where they can be found together with a collection of relevant articles from other Nature Publishing Group journals.