Milestones in cell division. Nature Milestones (Suppl.) December (2001). A joint project between Nature Cell Biology, Nature Reviews Molecular Cell Biology, Nature and Nature Reviews Cancer to highlight many of the most important discoveries in cell division. This supplement, containing Highlight articles, original research papers and relevant reviews, is also accompanied by a special web focus.

BAC to the future: the use of BAC transgenic mice for CNS research. Heintz, N. Nature Reviews Neuroscience December (2001)

Alfred Nobel — his life and work. Ringertz, N. Nature Reviews Molecular Cell Biology December (2001) A Perspective article on this inventor and industrialist that coincides with the centenary of the Nobel prize awards.

Emerging links between DNA polymerases and hypermutation of antibody genes. Gearhart, P. J. & Wood, R. D. Nature Reviews Immunology December (2001) This Review article discusses new insights into the mechanisms by which somatic hypermutations in immunoglobulin V are generated.

Chromosome translocations: dangerous liaisons revisited. Rowley, R. D. Nature Reviews Cancer December (2001) A Perspective article on the link between chromosomal translocations and tumorigenesis.

FRA3B and other common fragile sites: the weakest links. Huebner, K. & Croce, C. M. Nature Reviews Cancer December (2001)

Size matters to a telomere. Bonetta, L. Nature Medicine November (2001) This News and Views article discusses recent findings that the response of a cell to telomere shortening depends on the shortest telomere within the cell — once detected, a very short telomere is treated by the cell as a DNA break.

Insight on stem cells. Nature 1 November (2001) A collection of reviews, progress articles and commentaries on stem cell biology, which include: The future for stem cell research. Lovell-Badge, R. Reprogramming of genome function through epigenetic inheritance. Surani, M. A. Ethical and social considerations of stem cell research. McLaren, A.