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| Open AccessDepdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway
- Lin Xu
- , Xinge Zhang
- & Xuan Cao
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Article
| Open AccessGlobal transcriptomic changes in glomerular endothelial cells in mice with podocyte depletion and glomerulosclerosis
- Jia Fu
- , Zhengzi Yi
- & John Cijiang He
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Article
| Open AccessExosomal annexin A6 induces gemcitabine resistance by inhibiting ubiquitination and degradation of EGFR in triple-negative breast cancer
- Ting Li
- , Zhonghua Tao
- & Xichun Hu
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Article
| Open AccessOperative ubiquitin-specific protease 22 deubiquitination confers a more invasive phenotype to cholangiocarcinoma
- Yu Tian
- , Bo Tang
- & Liming Wang
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Article
| Open AccessDownregulated lncRNA RCPCD promotes differentiation of embryonic stem cells into cardiac pacemaker-like cells by suppressing HCN4 promoter methylation
- Ye Zhu
- , Jia You
- & Xiang Gu
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Article
| Open AccessClinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models
- Michelle P. Clark
- , Thao Huynh
- & Gregor Ebert
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Article
| Open AccessNecroptosis protects against exacerbation of acute pancreatitis
- Michittra Boonchan
- , Hideki Arimochi
- & Koji Yasutomo
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Review Article
| Open AccessEmerging understanding of apoptosis in mediating mesenchymal stem cell therapy
- Yu Fu
- , Bingdong Sui
- & Xuefeng Hu
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Article
| Open AccessLncRNA LINC00473 is involved in the progression of invasive pituitary adenoma by upregulating KMT5A via ceRNA-mediated miR-502-3p evasion
- Junjun Li
- , Yuan Qian
- & Xingli Deng
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Article
| Open AccessIL-37b alleviates endothelial cell apoptosis and inflammation in Kawasaki disease through IL-1R8 pathway
- Chang Jia
- , Yingzhi Zhuge
- & Maoping Chu
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Article
| Open AccessTargeting STAT3 signaling overcomes gefitinib resistance in non-small cell lung cancer
- Zhe Liu
- , Liang Ma
- & Xue Wang
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Review Article
| Open AccessRoles of tRNA metabolism in aging and lifespan
- Zheng Zhou
- , Bao Sun
- & Meng Bian
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Article
| Open AccessBKM120 sensitizes glioblastoma to the PARP inhibitor rucaparib by suppressing homologous recombination repair
- Shaolu Zhang
- , Xin Peng
- & Dexin Kong
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Article
| Open AccessResistance of bone marrow stroma to genotoxic preconditioning is determined by p53
- Natalia Fedtsova
- , Elena A. Komarova
- & Andrei V. Gudkov
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Article
| Open AccessLet-7f miRNA regulates SDF-1α- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release
- Virginia Egea
- , Kai Kessenbrock
- & Christian Ries
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Article
| Open AccessMonocytic MDSC mobilization promotes tumor recurrence after liver transplantation via CXCL10/TLR4/MMP14 signaling
- Hui Liu
- , Chang Chun Ling
- & Kwan Man
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Article
| Open AccessTargeting epigenetic modulation of cholesterol synthesis as a therapeutic strategy for head and neck squamous cell carcinoma
- Xing Xu
- , Jun Chen
- & Xu Wang
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Article
| Open AccessKartogenin prevents cartilage degradation and alleviates osteoarthritis progression in mice via the miR-146a/NRF2 axis
- Mingzhuang Hou
- , Yijian Zhang
- & Xuesong Zhu
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Article
| Open AccessKnockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy
- Lu Zhang
- , Jiaqi He
- & Lingjun Wang
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Article
| Open AccessInhibition of the sonic hedgehog pathway activates TGF-β-activated kinase (TAK1) to induce autophagy and suppress apoptosis in thyroid tumor cells
- Sumei Li
- , Jingxiang Wang
- & Xiulong Xu
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Article
| Open AccessInterrogation of gender disparity uncovers androgen receptor as the transcriptional activator for oncogenic miR-125b in gastric cancer
- Ben Liu
- , Meng Zhou
- & Kexin Chen
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Article
| Open AccessThe hypoxia sensitive metal transcription factor MTF-1 activates NCX1 brain promoter and participates in remote postconditioning neuroprotection in stroke
- Valeria Valsecchi
- , Giusy Laudati
- & Giuseppe Pignataro
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Article
| Open AccessAnti-tumor activity of a novel proteasome inhibitor D395 against multiple myeloma and its lower cardiotoxicity compared with carfilzomib
- Xuxing Shen
- , Chao Wu
- & Lijuan Chen
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Article
| Open AccessPermissive effect of GSK3β on profibrogenic plasticity of renal tubular cells in progressive chronic kidney disease
- Bohan Chen
- , Pei Wang
- & Rujun Gong
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Article
| Open AccessGlucocorticoid-induced leucine zipper regulates liver fibrosis by suppressing CCL2-mediated leukocyte recruitment
- Sara Flamini
- , Philipp Sergeev
- & Stefano Bruscoli
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Article
| Open AccessFGF23 ameliorates ischemia-reperfusion induced acute kidney injury via modulation of endothelial progenitor cells: targeting SDF-1/CXCR4 signaling
- Huang-Ming Chang
- , Kang-Yung Peng
- & Vin-Cent Wu
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Article
| Open AccessATF3 deficiency impairs the proliferative–secretory phase transition and decidualization in RIF patients
- Zhilong Wang
- , Yang Liu
- & Guijun Yan
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Article
| Open AccessCellular fate of intersex differentiation
- Xin Wang
- , Fengling Lai
- & Rongjia Zhou
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Article
| Open AccessDevelopment of a bispecific immune engager using a recombinant malaria protein
- Mie A. Nordmaj
- , Morgan E. Roberts
- & Ali Salanti
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Article
| Open AccessEradication of specific donor-dependent variations of mesenchymal stem cells in immunomodulation to enhance therapeutic values
- Chunxue Zhang
- , Liqiang Zhou
- & Yi Eve Sun
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Article
| Open AccessUtidelone inhibits growth of colorectal cancer cells through ROS/JNK signaling pathway
- Fuli Li
- , Tinglei Huang
- & Shuiping Tu
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Article
| Open AccessThe deubiquitinating enzyme USP15 stabilizes ERα and promotes breast cancer progression
- Xiaohong Xia
- , Chuyi Huang
- & Hongbiao Huang
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Article
| Open AccessA protective role for autophagy in vitiligo
- Emanuela Bastonini
- , Daniela Kovacs
- & Mauro Picardo
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Article
| Open AccessOleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2α/ATF4/CHOP pathway in breast cancer
- Xiaoxi Li
- , Jian Zheng
- & Shu-lan Sun
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Article
| Open AccessFoxP3-miR-150-5p/3p suppresses ovarian tumorigenesis via an IGF1R/IRS1 pathway feedback loop
- Qinkai Zhang
- , Xunzhu Zhou
- & Jianmin Wu
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Article
| Open AccessPhosphatase PP2A enhances MCL-1 protein half-life in multiple myeloma cells
- Anne Slomp
- , Laura M. Moesbergen
- & Victor Peperzak
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Article
| Open AccessMutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane
- Vinaya Phatak
- , Yannick von Grabowiecki
- & Patricia A. J. Muller
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Article
| Open AccessPolycysteine as a new type of radio-protector ameliorated tissue injury through inhibiting ferroptosis in mice
- Junling Zhang
- , Kui Li
- & Hongqi Tian
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Article
| Open AccessAkt kinase LANCL2 functions as a key driver in EGFR-mutant lung adenocarcinoma tumorigenesis
- Yuqing Lou
- , Jianlin Xu
- & Baohui Han
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Article
| Open AccessThe necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis
- Diane Moujalled
- , Pradnya Gangatirkar
- & Emma C. Josefsson
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Article
| Open AccessEfficient clofilium tosylate-mediated rescue of POLG-related disease phenotypes in zebrafish
- Nicola Facchinello
- , Claudio Laquatra
- & Natascia Tiso
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Article
| Open AccessInhibition of histone methyltransferase G9a attenuates liver cancer initiation by sensitizing DNA-damaged hepatocytes to p53-induced apoptosis
- Takuma Nakatsuka
- , Keisuke Tateishi
- & Kazuhiko Koike
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Article
| Open AccessArsenic trioxide induces macrophage autophagy and atheroprotection by regulating ROS-dependent TFEB nuclear translocation and AKT/mTOR pathway
- Shaohong Fang
- , Xin Wan
- & Bo Yu
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Article
| Open AccessGNA13 regulates BCL2 expression and the sensitivity of GCB-DLBCL cells to BCL2 inhibitors in a palmitoylation-dependent manner
- Zhizhou Xia
- , Xiuli Zhang
- & Ruibao Ren
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Article
| Open AccessMEX3A contributes to development and progression of glioma through regulating cell proliferation and cell migration and targeting CCL2
- Chao Yang
- , Haoqiang Zhan
- & Heping Wang
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Article
| Open AccessAdult mesenchymal stem cell ageing interplays with depressed mitochondrial Ndufs6
- Yuelin Zhang
- , Liyan Guo
- & Qizhou Lian
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Article
| Open AccessPhosphorylation of eIF2α signaling pathway attenuates obesity-induced non-alcoholic fatty liver disease in an ER stress and autophagy-dependent manner
- Jie Li
- , Xinle Li
- & Ping Zhang
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Article
| Open AccessPeroxiredoxin 4 protects against ovarian ageing by ameliorating d-galactose-induced oxidative damage in mice
- Xiuru Liang
- , Zhengjie Yan
- & Yan Meng
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Article
| Open AccessHPV E7-mediated NCAPH ectopic expression regulates the carcinogenesis of cervical carcinoma via PI3K/AKT/SGK pathway
- Meng Wang
- , Xiaowen Qiao
- & Xiao Wang