Article
|
Open Access
Featured
-
-
Article
| Open AccessOsimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans
- J. M. Vicencio
- , R. Evans
- & T. Ng
-
Article
| Open AccessLPS/Bcl3/YAP1 signaling promotes Sox9+HNF4α+ hepatocyte-mediated liver regeneration after hepatectomy
- Changchun Shao
- , Yingying Jing
- & Lixin Wei
-
Article
| Open AccessMesenchymal stem cells protect against ferroptosis via exosome-mediated stabilization of SLC7A11 in acute liver injury
Schematic diagram of the protective effect of MSC-derived exosomes on maintaining SLC7A11 function during ferroptosis involved in CCl4-induced ALI.
- Feiyan Lin
- , Wenyi Chen
- & Hongcui Cao
-
Review Article
| Open AccessTherapeutic approaches targeting CD95L/CD95 signaling in cancer and autoimmune diseases
- Vesna Risso
- , Elodie Lafont
- & Matthieu Le Gallo
-
Article
| Open AccessPlasma proteomic and metabolomic characterization of COVID-19 survivors 6 months after discharge
- Hongwei Li
- , Xue Li
- & Huaiyong Chen
-
Article
| Open AccessToll-like receptor 3 activation promotes joint degeneration in osteoarthritis
- Josef Stolberg-Stolberg
- , Annika Boettcher
- & Jessica Bertrand
-
Article
| Open AccessLeptin secreted from testicular microenvironment modulates hedgehog signaling to augment the endogenous function of Leydig cells
- Himanshu Arora
- , Rehana Qureshi
- & Ranjith Ramasamy
-
Article
| Open AccessSF3B4 promotes ovarian cancer progression by regulating alternative splicing of RAD52
- Yuchao Diao
- , Yingwei Li
- & Beihua Kong
-
Article
| Open AccessExosome-mediated miR-7-5p delivery enhances the anticancer effect of Everolimus via blocking MNK/eIF4E axis in non-small cell lung cancer
- Sile Liu
- , Weiyuan Wang
- & Songqing Fan
-
Article
| Open AccessIncreased MCL-1 synthesis promotes irradiation-induced nasopharyngeal carcinoma radioresistance via regulation of the ROS/AKT loop
- Ying-Ying Liang
- , Fei-Yu Niu
- & Ya-Wei Yuan
-
Article
| Open AccessPGK1 contributes to tumorigenesis and sorafenib resistance of renal clear cell carcinoma via activating CXCR4/ERK signaling pathway and accelerating glycolysis
- Yu He
- , Xixi Wang
- & Shufang Liang
-
Article
| Open AccessLong non-coding RNA PAARH promotes hepatocellular carcinoma progression and angiogenesis via upregulating HOTTIP and activating HIF-1α/VEGF signaling
- Huamei Wei
- , Zuoming Xu
- & Jian Pu
-
Article
| Open AccessAdenine overload induces ferroptosis in human primary proximal tubular epithelial cells
- Muhammad Ali Khan
- , Purba Nag
- & Andrew J. Kassianos
-
Article
| Open AccessThe EMT-induced lncRNA NR2F1-AS1 positively modulates NR2F1 expression and drives gastric cancer via miR-29a-3p/VAMP7 axis
- Dandan Li
- , Mengjie Xu
- & Shanshan Qin
-
Article
| Open AccessGlucose-regulated protein 78 modulates cell growth, epithelial–mesenchymal transition, and oxidative stress in the hyperplastic prostate
- Xun Fu
- , Jianmin Liu
- & Xinhua Zhang
-
Article
| Open AccessEpimedium protects against dyszoospermia in mice with Pex3 knockout by exerting antioxidant effects and regulating the expression level of P16
- Haiyang Zhao
- , Tingting Zhao
- & Yun Qian
-
Article
| Open AccessSTAT6 contributes to renal fibrosis by modulating PPARα-mediated tubular fatty acid oxidation
- Jianzhong Li
- , Youjing Yang
- & Shasha Tao
-
Review Article
| Open AccessExtracellular vesicles in ovarian cancer chemoresistance, metastasis, and immune evasion
- Wanjia Tian
- , Ningjing Lei
- & Lei Chang
-
Article
| Open AccessBlocking autophagy overcomes resistance to dual histone deacetylase and proteasome inhibition in gynecologic cancer
- Jianling Bi
- , Yuping Zhang
- & Kimberly K. Leslie
-
Article
| Open AccessPGC-1α inhibits the NLRP3 inflammasome via preserving mitochondrial viability to protect kidney fibrosis
- Bo Young Nam
- , Jong Hyun Jhee
- & Seung Hyeok Han
-
Article
| Open AccessLong noncoding RNA Meg3 sponges miR-708 to inhibit intestinal tumorigenesis via SOCS3-repressed cancer stem cells growth
- Shuo Zhang
- , Wei-Wei Ji
- & Xuan Huang
-
Article
| Open AccessNLPR3 inflammasome inhibition alleviates hypoxic endothelial cell death in vitro and protects blood–brain barrier integrity in murine stroke
- Maximilian Bellut
- , Lena Papp
- & Michael K. Schuhmann
-
Article
| Open AccessThe BH3-only protein NOXA serves as an independent predictor of breast cancer patient survival and defines susceptibility to microtubule targeting agents
- Gerlinde Karbon
- , Manuel D. Haschka
- & Andreas Villunger
-
Article
| Open AccessChemotoxicity-induced exosomal lncFERO regulates ferroptosis and stemness in gastric cancer stem cells
- Haiyang Zhang
- , Meng Wang
- & Yi Ba
-
Article
| Open AccessLong non-coding RNA HOMER3-AS1 drives hepatocellular carcinoma progression via modulating the behaviors of both tumor cells and macrophages
- Jian Pu
- , Wenchuan Li
- & Huamei Wei
-
Article
| Open AccessMolecular and histological traits of reduced lysosomal acid lipase activity in the fatty liver
- Simone Carotti
- , Daniele Lettieri-Barbato
- & Umberto Vespasiani-Gentilucci
-
Article
| Open AccessIL-17A injury to retinal ganglion cells is mediated by retinal Müller cells in diabetic retinopathy
- Ao-Wang Qiu
- , Da-Rui Huang
- & Qing-Huai Liu
-
Article
| Open AccessAnnexinA7 promotes epithelial–mesenchymal transition by interacting with Sorcin and contributes to aggressiveness in hepatocellular carcinoma
- Fei Ling
- , Huan Zhang
- & Jun Zhang
-
Article
| Open Accessp62/SQSTM1-induced caspase-8 aggresomes are essential for ionizing radiation-mediated apoptosis
- Su Hyun Lee
- , Won Jin Cho
- & Hyeong-Reh C. Kim
-
Article
| Open AccessTargeting LSD1 suppresses stem cell-like properties and sensitizes head and neck squamous cell carcinoma to PD-1 blockade
- Yong Han
- , Shengming Xu
- & Shuli Liu
-
Review Article
| Open AccessThe emerging roles of neutrophil extracellular traps in wound healing
- Shuainan Zhu
- , Ying Yu
- & Kefang Guo
-
Article
| Open AccessSmooth muscle 22 alpha protein inhibits VSMC foam cell formation by supporting normal LXRα signaling, ameliorating atherosclerosis
- Dan-Dan Zhang
- , Yu Song
- & Mei Han
-
Article
| Open AccessThe interaction of S100A16 and GRP78 actives endoplasmic reticulum stress-mediated through the IRE1α/XBP1 pathway in renal tubulointerstitial fibrosis
- Runbing Jin
- , Anran Zhao
- & Xiubin Liang
-
Article
| Open AccessPARK7 promotes repair in early steroid-induced osteonecrosis of the femoral head by enhancing resistance to stress-induced apoptosis in bone marrow mesenchymal stem cells via regulation of the Nrf2 signaling pathway
- Fei Zhang
- , Yanglin Yan
- & Wentao Dong
-
Article
| Open AccessAMPK agonist alleviate renal tubulointerstitial fibrosis via activating mitophagy in high fat and streptozotocin induced diabetic mice
- Ya-chun Han
- , Shi-qi Tang
- & Shikun Yang
-
Article
| Open AccessTDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease
- Rachel E. Carlisle
- , Zahraa Mohammed-Ali
- & Jeffrey G. Dickhout
-
Article
| Open AccessEpithelial argininosuccinate synthetase is dispensable for intestinal regeneration and tumorigenesis
- Jonathan H. M. van der Meer
- , Ruben J. de Boer
- & Vanesa Muncan
-
Article
| Open AccessModulation of oxidative phosphorylation augments antineoplastic activity of mitotic aurora kinase inhibition
- Zijian Zhang
- , Deshun Zeng
- & Zifeng Wang
-
Article
| Open AccessCombination of tyrosine kinase inhibitors and the MCL1 inhibitor S63845 exerts synergistic antitumorigenic effects on CML cells
- Alena Malyukova
- , Dorina Ujvari
- & Daniel Salamon
-
Article
| Open AccessCardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload
- Yan Zou
- , Le Pan
- & Junbo Ge
-
Article
| Open AccessAutophagic secretion of HMGB1 from cancer-associated fibroblasts promotes metastatic potential of non-small cell lung cancer cells via NFκB signaling
- Yinghui Ren
- , Limin Cao
- & Ke Xu
-
Article
| Open AccessSelective degradation of AR-V7 to overcome castration resistance of prostate cancer
- Yuan Liu
- , Cuifu Yu
- & Hongbiao Huang
-
Article
| Open AccessCISD3 inhibition drives cystine-deprivation induced ferroptosis
- Yanchun Li
- , Xin Wang
- & Ying Wang
-
Review Article
| Open AccessDynamic regulation of mitochondrial-endoplasmic reticulum crosstalk during stem cell homeostasis and aging
- Weiping Lin
- , Shuxun Chen
- & Gang Li
-
Article
| Open AccessAlcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation
- Stefanie Meier
- , Sandra Cantilena
- & David Michod
-
Article
| Open AccessCaspase-8 mutations associated with head and neck cancer differentially retain functional properties related to TRAIL-induced apoptosis and cytokine induction
- Zhibin Cui
- , Hadas Dabas
- & Daniel E. Johnson
-
Article
| Open AccessThromboembolism after COVID-19 vaccine in patients with preexisting thrombocytopenia
- Alessandro Mauriello
- , Manuel Scimeca
- & Gerry Melino
-
Article
| Open AccessmiR-526b-3p inhibits lung cancer cisplatin-resistance and metastasis by inhibiting STAT3-promoted PD-L1
- Kuan-bing Chen
- , Wei Yang
- & Ai-jun Lin
-
Article
| Open AccessGPX4 and vitamin E cooperatively protect hematopoietic stem and progenitor cells from lipid peroxidation and ferroptosis
- Qian Hu
- , Yifan Zhang
- & Zhenyu Ju