Featured
-
-
Article
| Open AccessTonic excitation by astrocytic GABA causes neuropathic pain by augmenting neuronal activity and glucose metabolism
- Yeon Ha Ju
- , Jongwook Cho
- & Min-Ho Nam
-
Review Article
| Open AccessGlycerol 3-phosphate dehydrogenases (1 and 2) in cancer and other diseases
- Sehyun Oh
- , Xuan Linh Mai
- & Sunghyouk Park
-
Review Article
| Open AccessParadigm shift required for translational research on the brain
- Jong Hyuk Yoon
- , Dongha Lee
- & Pann-Ghill Suh
-
Article
| Open AccessMrgprb2-mediated mast cell activation exacerbates Modic changes by regulating immune niches
- Zhongyin Ji
- , Jie Li
- & Fengdong Zhao
-
Article
| Open AccessTargeting pyruvate dehydrogenase kinase 1 overcomes EGFR C797S mutation-driven osimertinib resistance in non-small cell lung cancer
- Wonyoung Park
- , Shibo Wei
- & Ki-Tae Ha
-
Editorial
| Open Access4D nucleome: dynamic three-dimensional genome organization over time
- Hyoung-Pyo Kim
-
Review Article
| Open AccessViral remodeling of the 4D nucleome
- Kyoung-Dong Kim
- & Paul M. Lieberman
-
Review Article
| Open AccessTransmembrane proteins with unknown function (TMEMs) as ion channels: electrophysiological properties, structure, and pathophysiological roles
- Hyunji Kang
- & C. Justin Lee
-
Article
| Open AccessMethyl-CpG binding domain protein 2 (Mbd2) drives breast cancer progression through the modulation of epithelial-to-mesenchymal transition
- Niaz Mahmood
- , Ani Arakelian
- & Shafaat A. Rabbani
-
Article
| Open AccessAge-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure
- Youngbum Yoo
- , MyeongHoon Yeon
- & Young-Kyo Seo
-
Article
| Open AccessThe acute phase reactant orosomucoid-2 directly promotes rheumatoid inflammation
- Ki-Myo Kim
- , Kang-Gu Lee
- & Wan-Uk Kim
-
Article
| Open AccessExperimental capture of miRNA targetomes: disease-specific 3′UTR library-based miRNA targetomics for Parkinson’s disease
- Martin Hart
- , Fabian Kern
- & Eckart Meese
-
Article
| Open AccessInvolvement of DJ-1 in the pathogenesis of intervertebral disc degeneration via hexokinase 2-mediated mitophagy
- Jialiang Lin
- , Longjie Wang
- & Weishi Li
-
Article
| Open AccessAcetyl-CoA synthetase 2 contributes to a better prognosis for liver cancer by switching acetate-glucose metabolism
- Kyung Hee Jung
- , Sujin Lee
- & Soon-Sun Hong
-
Article
| Open AccessPrmt7 regulates the JAK/STAT/Socs3 signaling pathway in postmenopausal cardiomyopathy
- Byeong-Yun Ahn
- , Yan Zhang
- & Jong-Sun Kang
-
Review Article
| Open AccessExtramedullary hematopoiesis in cancer
- Derek A. G. Barisas
- & Kyunghee Choi
-
Article
| Open AccessThe Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress
- Dae Jin Jeong
- , Jee-Hyun Um
- & Jeanho Yun
-
Article
| Open AccessAdvances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance biological interpretability
- Ken Takasawa
- , Ken Asada
- & Ryuji Hamamoto
-
Article
| Open AccessSynergistic toxicity with copper contributes to NAT2-associated isoniazid toxicity
- Jihoon G. Yoon
- , Dong Geon Jang
- & Min Goo Lee
-
Article
| Open AccessMechanical overload-induced release of extracellular mitochondrial particles from tendon cells leads to inflammation in tendinopathy
- Ziming Chen
- , Mengyuan Li
- & Ming H. Zheng
-
Review Article
| Open AccessHypoxia, oxidative stress, and the interplay of HIFs and NRF2 signaling in cancer
- Taegeun Bae
- , Steffanus Pranoto Hallis
- & Mi-Kyoung Kwak
-
Article
| Open AccessRNA m5C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer
- Xiaoyi Liu
- , Qinglv Wei
- & Ping Yi
-
Article
| Open AccessRole of lung ornithine aminotransferase in idiopathic pulmonary fibrosis: regulation of mitochondrial ROS generation and TGF-β1 activity
- Jong-Uk Lee
- , Ki Sung Song
- & Sung-Woo Park
-
Article
| Open AccessNOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells
- Hye Yeon Choi
- , Yicheng Zhu
- & Keigo Machida
-
Review Article
| Open AccessEmerging roles of MITF as a crucial regulator of immunity
- Aram Lee
- , Jihyun Lim
- & Jong-Seok Lim
-
Article
| Open AccessNucleus pulposus cells regulate macrophages in degenerated intervertebral discs via the integrated stress response-mediated CCL2/7-CCR2 signaling pathway
- Shuo Tian
- , Xuanzuo Chen
- & Yizhong Peng
-
Article
| Open AccessThe deubiquitinase USP40 preserves endothelial integrity by targeting the heat shock protein HSP90β
- Jiaxing Miao
- , Lian Li
- & Jing Zhao
-
Review Article
| Open AccessRegulation of autophagy by perilysosomal calcium: a new player in β-cell lipotoxicity
- Ha Thu Nguyen
- , Andreas Wiederkehr
- & Kyu-Sang Park
-
Review Article
| Open AccessHIRA vs. DAXX: the two axes shaping the histone H3.3 landscape
- Jinmi Choi
- , Taewan Kim
- & Eun-Jung Cho
-
Article
| Open AccessSynaptotagmin-4 induces anhedonic responses to chronic stress via BDNF signaling in the medial prefrontal cortex
- Jeongseop Kim
- , Sihwan Seol
- & Hyo Jung Kang
-
Article
| Open AccessTargeting the m6A RNA methyltransferase METTL3 attenuates the development of kidney fibrosis
- Hae Rim Jung
- , Jeonghwan Lee
- & Sung-Yup Cho
-
Article
| Open AccessCYB5R3 functions as a tumor suppressor by inducing ER stress-mediated apoptosis in lung cancer cells via the PERK-ATF4 and IRE1α-JNK pathways
- Joo-Young Im
- , Soo Jin Kim
- & Misun Won
-
Article
| Open AccessThe polyol pathway and nuclear ketohexokinase A signaling drive hyperglycemia-induced metastasis of gastric cancer
- Ye-Lim Kang
- , Jiyoung Kim
- & Jong-Wan Park
-
Article
| Open AccessMaintaining Drosha expression with Cdk5 inhibitors as a potential therapeutic strategy for early intervention after TBI
- Lu Huang
- , Li Xia
- & Qian Yang
-
Review Article
| Open AccessSignificance of chitinase-3-like protein 1 in the pathogenesis of inflammatory diseases and cancer
- Ji Eun Yu
- , In Jun Yeo
- & Jin Tae Hong
-
Review Article
| Open AccessCurrent understanding of the Alzheimer’s disease-associated microbiome and therapeutic strategies
- Dong-oh Seo
- & David M. Holtzman
-
Review Article
| Open AccessMitochondria as secretory organelles and therapeutic cargos
- Joonho Suh
- & Yun-Sil Lee
-
Article
| Open AccessVitamin D ameliorates age-induced nonalcoholic fatty liver disease by increasing the mitochondrial contact site and cristae organizing system (MICOS) 60 level
- Gyu Hee Kim
- , Hyeon-Ju Jeong
- & Joo Hyun Lim
-
Article
| Open AccessWTAP-mediated m6A modification of FRZB triggers the inflammatory response via the Wnt signaling pathway in osteoarthritis
- Xueying An
- , Rongliang Wang
- & Xingquan Xu
-
Article
| Open AccessElevated expression of WSB2 degrades p53 and activates the IGFBP3-AKT-mTOR-dependent pathway to drive hepatocellular carcinoma
- Xun Li
- , Cheng-Cheng Zhang
- & Chuan-Ming Xie
-
Article
| Open AccessSpatial architectures of somatic mutations in normal prostate, benign prostatic hyperplasia and coexisting prostate cancer
- Jeesoo Chae
- , Seung-Hyun Jung
- & Sug Hyung Lee
-
Correspondence
| Open AccessPiezo channels in the urinary system: Correspondence
- Shuaishuai Hu
- & Xudong Yao
-
Review Article
| Open AccessAortic aneurysms: current pathogenesis and therapeutic targets
- Min Ji Cho
- , Mi-Ran Lee
- & Jong-Gil Park
-
Review Article
| Open AccessTumor-suppressive functions of protein lysine methyltransferases
- Nur Aziz
- , Yo Han Hong
- & Jae Youl Cho
-
Article
| Open AccessDisruption of cholesterol homeostasis triggers periodontal inflammation and alveolar bone loss
- Thanh-Tam Tran
- , Gyuseok Lee
- & Je-Hwang Ryu
-
Article
| Open AccessPrecise base editing without unintended indels in human cells and mouse primary myoblasts
- Da Eun Yoon
- , Na-Rae Kim
- & Kyoungmi Kim
-
Article
| Open AccessSpatiotemporal characterization of glial cell activation in an Alzheimer’s disease model by spatially resolved transcriptomics
- Hongyoon Choi
- , Eun Ji Lee
- & Dong Soo Lee
-
Article
| Open AccessIgSF11 deficiency alleviates osteoarthritis in mice by suppressing early subchondral bone changes
- Gyeong Min Kim
- , Jihee Kim
- & Soo Young Lee
-
Review Article
| Open AccessSensing the oxygen and temperature in the adipose tissues – who’s sensing what?
- Gi-Sue Kang
- , Hye-Ju Jo
- & G-One Ahn