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Review Article
| Open AccessGlycerol 3-phosphate dehydrogenases (1 and 2) in cancer and other diseases
- Sehyun Oh
- , Xuan Linh Mai
- & Sunghyouk Park
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Article
| Open AccessTargeting pyruvate dehydrogenase kinase 1 overcomes EGFR C797S mutation-driven osimertinib resistance in non-small cell lung cancer
- Wonyoung Park
- , Shibo Wei
- & Ki-Tae Ha
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Review Article
| Open AccessTransmembrane proteins with unknown function (TMEMs) as ion channels: electrophysiological properties, structure, and pathophysiological roles
- Hyunji Kang
- & C. Justin Lee
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Article
| Open AccessMethyl-CpG binding domain protein 2 (Mbd2) drives breast cancer progression through the modulation of epithelial-to-mesenchymal transition
- Niaz Mahmood
- , Ani Arakelian
- & Shafaat A. Rabbani
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Article
| Open AccessThe acute phase reactant orosomucoid-2 directly promotes rheumatoid inflammation
- Ki-Myo Kim
- , Kang-Gu Lee
- & Wan-Uk Kim
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Article
| Open AccessExperimental capture of miRNA targetomes: disease-specific 3′UTR library-based miRNA targetomics for Parkinson’s disease
- Martin Hart
- , Fabian Kern
- & Eckart Meese
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Article
| Open AccessAcetyl-CoA synthetase 2 contributes to a better prognosis for liver cancer by switching acetate-glucose metabolism
- Kyung Hee Jung
- , Sujin Lee
- & Soon-Sun Hong
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Article
| Open AccessPrmt7 regulates the JAK/STAT/Socs3 signaling pathway in postmenopausal cardiomyopathy
- Byeong-Yun Ahn
- , Yan Zhang
- & Jong-Sun Kang
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Review Article
| Open AccessExtramedullary hematopoiesis in cancer
- Derek A. G. Barisas
- & Kyunghee Choi
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Article
| Open AccessThe Mst1/2-BNIP3 axis is required for mitophagy induction and neuronal viability under mitochondrial stress
- Dae Jin Jeong
- , Jee-Hyun Um
- & Jeanho Yun
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Article
| Open AccessAdvances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance biological interpretability
- Ken Takasawa
- , Ken Asada
- & Ryuji Hamamoto
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Review Article
| Open AccessHypoxia, oxidative stress, and the interplay of HIFs and NRF2 signaling in cancer
- Taegeun Bae
- , Steffanus Pranoto Hallis
- & Mi-Kyoung Kwak
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Article
| Open AccessRNA m5C modification upregulates E2F1 expression in a manner dependent on YBX1 phase separation and promotes tumor progression in ovarian cancer
- Xiaoyi Liu
- , Qinglv Wei
- & Ping Yi
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Article
| Open AccessSynergistic toxicity with copper contributes to NAT2-associated isoniazid toxicity
- Jihoon G. Yoon
- , Dong Geon Jang
- & Min Goo Lee
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Article
| Open AccessMechanical overload-induced release of extracellular mitochondrial particles from tendon cells leads to inflammation in tendinopathy
- Ziming Chen
- , Mengyuan Li
- & Ming H. Zheng
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Review Article
| Open AccessHIRA vs. DAXX: the two axes shaping the histone H3.3 landscape
- Jinmi Choi
- , Taewan Kim
- & Eun-Jung Cho
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Article
| Open AccessSynaptotagmin-4 induces anhedonic responses to chronic stress via BDNF signaling in the medial prefrontal cortex
- Jeongseop Kim
- , Sihwan Seol
- & Hyo Jung Kang
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Article
| Open AccessTargeting the m6A RNA methyltransferase METTL3 attenuates the development of kidney fibrosis
- Hae Rim Jung
- , Jeonghwan Lee
- & Sung-Yup Cho
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Article
| Open AccessCYB5R3 functions as a tumor suppressor by inducing ER stress-mediated apoptosis in lung cancer cells via the PERK-ATF4 and IRE1α-JNK pathways
- Joo-Young Im
- , Soo Jin Kim
- & Misun Won
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Article
| Open AccessMaintaining Drosha expression with Cdk5 inhibitors as a potential therapeutic strategy for early intervention after TBI
- Lu Huang
- , Li Xia
- & Qian Yang
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Review Article
| Open AccessSignificance of chitinase-3-like protein 1 in the pathogenesis of inflammatory diseases and cancer
- Ji Eun Yu
- , In Jun Yeo
- & Jin Tae Hong
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Review Article
| Open AccessCurrent understanding of the Alzheimer’s disease-associated microbiome and therapeutic strategies
- Dong-oh Seo
- & David M. Holtzman
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Article
| Open AccessVitamin D ameliorates age-induced nonalcoholic fatty liver disease by increasing the mitochondrial contact site and cristae organizing system (MICOS) 60 level
- Gyu Hee Kim
- , Hyeon-Ju Jeong
- & Joo Hyun Lim
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Article
| Open AccessWTAP-mediated m6A modification of FRZB triggers the inflammatory response via the Wnt signaling pathway in osteoarthritis
- Xueying An
- , Rongliang Wang
- & Xingquan Xu
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Article
| Open AccessElevated expression of WSB2 degrades p53 and activates the IGFBP3-AKT-mTOR-dependent pathway to drive hepatocellular carcinoma
- Xun Li
- , Cheng-Cheng Zhang
- & Chuan-Ming Xie
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Correspondence
| Open AccessPiezo channels in the urinary system: Correspondence
- Shuaishuai Hu
- & Xudong Yao
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Review Article
| Open AccessAortic aneurysms: current pathogenesis and therapeutic targets
- Min Ji Cho
- , Mi-Ran Lee
- & Jong-Gil Park
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Review Article
| Open AccessTumor-suppressive functions of protein lysine methyltransferases
- Nur Aziz
- , Yo Han Hong
- & Jae Youl Cho
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Article
| Open AccessIgSF11 deficiency alleviates osteoarthritis in mice by suppressing early subchondral bone changes
- Gyeong Min Kim
- , Jihee Kim
- & Soo Young Lee
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Review Article
| Open AccessSensing the oxygen and temperature in the adipose tissues – who’s sensing what?
- Gi-Sue Kang
- , Hye-Ju Jo
- & G-One Ahn
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Article
| Open AccessSARS-CoV-2 infection engenders heterogeneous ribonucleoprotein interactions to impede translation elongation in the lungs
- Junsoo Kim
- , Daehwa Youn
- & Jun Cho
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Article
| Open AccessAngiotensin receptor blockers, but not angiotensin-converting enzyme inhibitors, inhibit abnormal bone changes in spondyloarthritis
- Jin Sun Choi
- , Ji-Young Kim
- & Seung Cheol Shim
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Article
| Open AccessCircular RNA cFAM210A, degradable by HBx, inhibits HCC tumorigenesis by suppressing YBX1 transactivation
- Jian Yu
- , Wen Li
- & Fu Yang
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Article
| Open AccessLactobacillus plantarum ameliorates NASH-related inflammation by upregulating l-arginine production
- Dong Yun Kim
- , Jun Yong Park
- & Heon Yung Gee
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Article
| Open AccessKetohexokinase-dependent metabolism of cerebral endogenous fructose in microglia drives diabetes-associated cognitive dysfunction
- Yansong Li
- , Tao Jiang
- & Qiang Wang
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Review Article
| Open AccessTargeting E3 ubiquitin ligases and their adaptors as a therapeutic strategy for metabolic diseases
- Yelin Jeong
- , Ah-Reum Oh
- & KyeongJin Kim
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Article
| Open AccessVascular regeneration and skeletal muscle repair induced by long-term exposure to SDF-1α derived from engineered mesenchymal stem cells after hindlimb ischemia
- Jin-Ju Kim
- , Jae-Hyun Park
- & Hun-Jun Park
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Article
| Open AccessSystemic antibiotics cause deterioration of emphysema associated with exaggerated inflammation and autophagy
- Na Hyun Kim
- , Bo-Yun Choi
- & Sei Won Lee
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Article
| Open AccessTrametinib activates endogenous neurogenesis and recovers neuropathology in a model of Alzheimer’s disease
- Mi-Yeon Kim
- , Mi Jeong Kim
- & Sungho Han
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Article
| Open AccessLactobacillus-derived extracellular vesicles counteract Aβ42-induced abnormal transcriptional changes through the upregulation of MeCP2 and Sirt1 and improve Aβ pathology in Tg-APP/PS1 mice
- Hyejin Kwon
- , Eun-Hwa Lee
- & Pyung-Lim Han
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Review Article
| Open AccessFunctional significance of cholesterol metabolism in cancer: from threat to treatment
- Mingming Xiao
- , Jin Xu
- & Si Shi
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Article
| Open AccessThe CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by promoting autophagy in cardiomyocytes
- Dan Liu
- , Ruinan Xing
- & Yaling Han
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Article
| Open AccessElevated FBXL6 expression in hepatocytes activates VRK2-transketolase-ROS-mTOR-mediated immune evasion and liver cancer metastasis in mice
- Jie Zhang
- , Xiao-Tong Lin
- & Chuan-Ming Xie
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Review Article
| Open AccessMitochondria-associated programmed cell death as a therapeutic target for age-related disease
- Thanh T. Nguyen
- , Shibo Wei
- & Dongryeol Ryu
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Review Article
| Open AccessReg3γ: current understanding and future therapeutic opportunities in metabolic disease
- Jae Hoon Shin
- , Nadejda Bozadjieva-Kramer
- & Randy J. Seeley
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Article
| Open AccessALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression
- Guiwen Ye
- , Jinteng Li
- & Huiyong Shen
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Article
| Open AccessThrap3 promotes nonalcoholic fatty liver disease by suppressing AMPK-mediated autophagy
- Hyun-Jun Jang
- , Yo Han Lee
- & Jang Hyun Choi
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Article
| Open AccessInhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair
- Eunhwan Kim
- , Seol Hwa Seo
- & Kang-Yell Choi
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Article
| Open AccessSLC39A10 promotes malignant phenotypes of gastric cancer cells by activating the CK2-mediated MAPK/ERK and PI3K/AKT pathways
- Xiaojuan Ren
- , Chao Feng
- & Peng Hou
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