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Review Article
| Open Access
Paradigm shift required for translational research on the brain
- Jong Hyuk Yoon
- , Dongha Lee
- & Pann-Ghill Suh
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Editorial
| Open Access4D nucleome: dynamic three-dimensional genome organization over time
- Hyoung-Pyo Kim
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Review Article
| Open Access
Viral remodeling of the 4D nucleome
- Kyoung-Dong Kim
- & Paul M. Lieberman
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Article
| Open Access
Synergistic toxicity with copper contributes to NAT2-associated isoniazid toxicity
- Jihoon G. Yoon
- , Dong Geon Jang
- & Min Goo Lee
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Article
| Open Access
Mechanical overload-induced release of extracellular mitochondrial particles from tendon cells leads to inflammation in tendinopathy
- Ziming Chen
- , Mengyuan Li
- & Ming H. Zheng
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Article
| Open Access
Role of lung ornithine aminotransferase in idiopathic pulmonary fibrosis: regulation of mitochondrial ROS generation and TGF-β1 activity
- Jong-Uk Lee
- , Ki Sung Song
- & Sung-Woo Park
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Review Article
| Open Access
Emerging roles of MITF as a crucial regulator of immunity
- Aram Lee
- , Jihyun Lim
- & Jong-Seok Lim
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Article
| Open Access
The deubiquitinase USP40 preserves endothelial integrity by targeting the heat shock protein HSP90β
- Jiaxing Miao
- , Lian Li
- & Jing Zhao
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Article
| Open Access
The polyol pathway and nuclear ketohexokinase A signaling drive hyperglycemia-induced metastasis of gastric cancer
- Ye-Lim Kang
- , Jiyoung Kim
- & Jong-Wan Park
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Review Article
| Open Access
Mitochondria as secretory organelles and therapeutic cargos
- Joonho Suh
- & Yun-Sil Lee
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Article
| Open Access
Spatial architectures of somatic mutations in normal prostate, benign prostatic hyperplasia and coexisting prostate cancer
- Jeesoo Chae
- , Seung-Hyun Jung
- & Sug Hyung Lee
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Article
| Open Access
Disruption of cholesterol homeostasis triggers periodontal inflammation and alveolar bone loss
- Thanh-Tam Tran
- , Gyuseok Lee
- & Je-Hwang Ryu
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Article
| Open Access
Precise base editing without unintended indels in human cells and mouse primary myoblasts
- Da Eun Yoon
- , Na-Rae Kim
- & Kyoungmi Kim
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Article
| Open Access
Spatiotemporal characterization of glial cell activation in an Alzheimer’s disease model by spatially resolved transcriptomics
- Hongyoon Choi
- , Eun Ji Lee
- & Dong Soo Lee
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Review Article
| Open Access
Sensing the oxygen and temperature in the adipose tissues – who’s sensing what?
- Gi-Sue Kang
- , Hye-Ju Jo
- & G-One Ahn
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Article
| Open Access
Optimization of the optical transparency of bones by PACT-based passive tissue clearing
- Byung-Ho Jin
- , Jiwon Woo
- & Yong Eun Cho
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Review Article
| Open Access
A new era of macrophage-based cell therapy
- Yi Rang Na
- , Sang Wha Kim
- & Seung Hyeok Seok
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Article
| Open Access
Establishment of a humanized mouse model of keloid diseases following the migration of patient immune cells to the lesion: Patient-derived keloid xenograft (PDKX) model
- A Ram Lee
- , Seon-Yeong Lee
- & Mi-La Cho
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Review Article
| Open Access
Primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD): a condition exemplifying the crosstalk of the gut–liver axis
- You Sun Kim
- , Edward H. Hurley
- & Sungjin Ko
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Review Article
| Open Access
MicroRNA: trends in clinical trials of cancer diagnosis and therapy strategies
- Taewan Kim
- & Carlo M. Croce
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Article
| Open Access
Genomic characteristics of triple negative apocrine carcinoma: a comparison to triple negative breast cancer
- Ji-Yeon Kim
- , Sabin Park
- & Young-Hyuck Im
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Article
| Open Access
SOX17-mediated LPAR4 expression plays a pivotal role in cardiac development and regeneration after myocardial infarction
- Jin-Woo Lee
- , Choon-Soo Lee
- & Hyo-Soo Kim
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Review Article
| Open Access
TXNIP: A key protein in the cellular stress response pathway and a potential therapeutic target
- Eui-Hwan Choi
- & Sun-Ji Park
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Article
| Open Access
Decorin: a potential therapeutic candidate for ligamentum flavum hypertrophy by antagonizing TGF-β1
- Shanxi Wang
- , Yunkun Qu
- & Yang Liu
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Article
| Open Access
Mesenchymal stromal cells facilitate resolution of pulmonary fibrosis by miR-29c and miR-129 intercellular transfer
- Basalova Nataliya
- , Arbatskiy Mikhail
- & Efimenko Anastasiya
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Article
| Open Access
Etiopathogenic role of ERK5 signaling in sarcoma: prognostic and therapeutic implications
- Adrián Sánchez-Fdez
- , Sofía Matilla-Almazán
- & Azucena Esparís-Ogando
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Article
| Open Access
Peli3 ablation ameliorates acetaminophen-induced liver injury through inhibition of GSK3β phosphorylation and mitochondrial translocation
- Jaewon Lee
- , Jihoon Ha
- & Seok Hee Park
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Review Article
| Open Access
Trends and prospects in mitochondrial genome editing
- Hong Thi Lam Phan
- , Hyunji Lee
- & Kyoungmi Kim
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Article
| Open Access
Crystal structure of LRG1 and the functional significance of LRG1 glycan for LPHN2 activation
- Jimin Yang
- , Guo Nan Yin
- & Ho Min Kim
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Article
| Open Access
Insulin signaling is critical for sinoatrial node maintenance and function
- Sangmi Ock
- , Seong Woo Choi
- & Jaetaek Kim
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Article
| Open Access
Genomic and transcriptomic profiling reveal molecular characteristics of parathyroid carcinoma
- Se-Young Jo
- , Namki Hong
- & Yumie Rhee
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Article
| Open Access
Altered acylcarnitine metabolism and inflexible mitochondrial fuel utilization characterize the loss of neonatal myocardial regeneration capacity
- E. Kankuri
- , P. Finckenberg
- & E. Mervaala
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Article
| Open Access
CAR links hypoxia signaling to improved survival after myocardial infarction
- Fabian Freiberg
- , Meghna Thakkar
- & Michael Gotthardt
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Article
| Open Access
Levosimendan inhibits disulfide tau oligomerization and ameliorates tau pathology in TauP301L-BiFC mice
- Sungsu Lim
- , Seulgi Shin
- & Yun Kyung Kim
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Article
| Open Access
Whole-genome sequencing reveals an association between small genomic deletions and an increased risk of developing Parkinson’s disease
- Ji-Hye Oh
- , Sungyang Jo
- & Sun Ju Chung
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Review Article
| Open Access
Etiology of genetic muscle disorders induced by mutations in fast and slow skeletal MyBP-C paralogs
- Taejeong Song
- , Maicon Landim-Vieira
- & Sakthivel Sadayappan
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Article
| Open Access
BET inhibitors synergize with sunitinib in melanoma through GDF15 suppression
- Furong Zeng
- , Yayun Li
- & Guangtong Deng
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Article
| Open Access
Catecholamine induces Kupffer cell apoptosis via growth differentiation factor 15 in alcohol-associated liver disease
- Hee-Hoon Kim
- , Young-Ri Shim
- & Won-Il Jeong
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Article
| Open Access
Loss of KDM5B ameliorates pathological cardiac fibrosis and dysfunction by epigenetically enhancing ATF3 expression
- Bo Wang
- , Yong Tan
- & Zhenzhen Zhan
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Article
| Open Access
Induction of Nanog in neural progenitor cells for adaptive regeneration of ischemic brain
- Gyung-Ah Jung
- , Jin-A Kim
- & Il-Hoan Oh
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Article
| Open Access
The natural product salicin alleviates osteoarthritis progression by binding to IRE1α and inhibiting endoplasmic reticulum stress through the IRE1α-IκBα-p65 signaling pathway
- Zhenglin Zhu
- , Shengqiang Gao
- & Wei Huang
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Article
| Open Access
NRBF2-mediated autophagy contributes to metabolite replenishment and radioresistance in glioblastoma
- Jeongha Kim
- , Hyunkoo Kang
- & BuHyun Youn
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Article
| Open Access
An Fc variant with two mutations confers prolonged serum half-life and enhanced effector functions on IgG antibodies
- Sanghwan Ko
- , Sora Park
- & Sang Taek Jung
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Review Article
| Open AccessFerritin – a multifaceted protein scaffold for biotherapeutics
- Na Kyeong Lee
- , Seongeon Cho
- & In-San Kim
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Article
| Open Access
Machine-learning algorithms for asthma, COPD, and lung cancer risk assessment using circulating microbial extracellular vesicle data and their application to assess dietary effects
- Andrea McDowell
- , Juwon Kang
- & Yoon-Keun Kim
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Article
| Open Access
Clusterin negatively modulates mechanical stress-mediated ligamentum flavum hypertrophy through TGF-β1 signaling
- Chunlei Liu
- , Peng Li
- & Zhongmin Zhang
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Article
| Open Access
Preclinical investigation of artesunate as a therapeutic agent for hepatocellular carcinoma via impairment of glucosylceramidase-mediated autophagic degradation
- Wenjia Chen
- , Zhaochen Ma
- & Yanqiong Zhang
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Editorial
| Open AccessTracing metabolic flux in vivo: motion pictures differ from snapshots
- Il-Young Kim
- & Robert R. Wolfe
Exploiting sweet relief for preeclampsia by targeting autophagy-lysosomal machinery and proteinopathy