Health sciences

Definition

The health sciences study all aspects of health, disease and healthcare. This field of study aims to develop knowledge, interventions and technology for use in healthcare to improve the treatment of patients.

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Latest Research and Reviews

  • Reviews |

    Multiple myeloma — a malignancy of terminally differentiated plasma cells — is the second most common haematological malignancy. This Primer by Kumar et al. highlights the mechanisms and epidemiology of multiple myeloma, and describes how updates to the diagnostic criteria have impacted patient management.

    • Shaji K. Kumar
    • , Vincent Rajkumar
    • , Robert A. Kyle
    • , Mark van Duin
    • , Pieter Sonneveld
    • , María-Victoria Mateos
    • , Francesca Gay
    •  & Kenneth C. Anderson
  • Research |

    The cysteine protease CPR-4, a cathepsin B homologue, is identified as a radiation-induced bystander effect (RIBE) factor in nematodes in response to ultraviolet or ionizing radiation, and causes inhibition of cell death and increased embryonic lethality.

    • Yu Peng
    • , Man Zhang
    • , Lingjun Zheng
    • , Qian Liang
    • , Hanzeng Li
    • , Jeng-Ting Chen
    • , Hongyan Guo
    • , Sawako Yoshina
    • , Yu-Zen Chen
    • , Xiang Zhao
    • , Xiaoqi Wu
    • , Bin Liu
    • , Shohei Mitani
    • , Jau-Song Yu
    •  & Ding Xue
  • Research |

    In vivo CRISPR screening reveals that loss of Ptpn2 increases the response of tumour cells to immunotherapy and increases IFNγ signalling, suggesting that PTPN2 inhibition may potentiate the effect of immunotherapies that invoke an IFNγ response.

    • Robert T. Manguso
    • , Hans W. Pope
    • , Margaret D. Zimmer
    • , Flavian D. Brown
    • , Kathleen B. Yates
    • , Brian C. Miller
    • , Natalie B. Collins
    • , Kevin Bi
    • , Martin W. LaFleur
    • , Vikram R. Juneja
    • , Sarah A. Weiss
    • , Jennifer Lo
    • , David E. Fisher
    • , Diana Miao
    • , Eliezer Van Allen
    • , David E. Root
    • , Arlene H. Sharpe
    • , John G. Doench
    •  & W. Nicholas Haining

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