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| Open AccessMechanical overload-induced release of extracellular mitochondrial particles from tendon cells leads to inflammation in tendinopathy
- Ziming Chen
- , Mengyuan Li
- & Ming H. Zheng
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Article
| Open AccessNOTCH localizes to mitochondria through the TBC1D15-FIS1 interaction and is stabilized via blockade of E3 ligase and CDK8 recruitment to reprogram tumor-initiating cells
- Hye Yeon Choi
- , Yicheng Zhu
- & Keigo Machida
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Article
| Open AccessNucleus pulposus cells regulate macrophages in degenerated intervertebral discs via the integrated stress response-mediated CCL2/7-CCR2 signaling pathway
- Shuo Tian
- , Xuanzuo Chen
- & Yizhong Peng
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Article
| Open AccessHMGB1 induces hepcidin upregulation in astrocytes and causes an acute iron surge and subsequent ferroptosis in the postischemic brain
- Dashdulam Davaanyam
- , Hahnbi Lee
- & Ja-Kyeong Lee
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Article
| Open AccessEstablishment of a humanized mouse model of keloid diseases following the migration of patient immune cells to the lesion: Patient-derived keloid xenograft (PDKX) model
- A Ram Lee
- , Seon-Yeong Lee
- & Mi-La Cho
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Review Article
| Open AccessPrimary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD): a condition exemplifying the crosstalk of the gut–liver axis
- You Sun Kim
- , Edward H. Hurley
- & Sungjin Ko
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Review Article
| Open AccessTXNIP: A key protein in the cellular stress response pathway and a potential therapeutic target
- Eui-Hwan Choi
- & Sun-Ji Park
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Review Article
| Open AccessCancer-associated fibroblasts: from basic science to anticancer therapy
- Dakai Yang
- , Jing Liu
- & Qin Zhuang
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Article
| Open AccessAn MRTF-A–ZEB1–IRF9 axis contributes to fibroblast–myofibroblast transition and renal fibrosis
- Qianwen Zhao
- , Tinghui Shao
- & Tao Zhang
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| Open AccessDefining regorafenib as a senomorphic drug: therapeutic potential in the age-related lung disease emphysema
- Jung-Jin Park
- , Kwangseok Oh
- & Eung-Gook Kim
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Article
| Open AccessCCL12 induces trabecular bone loss by stimulating RANKL production in BMSCs during acute lung injury
- Chao Ma
- , Juan Gao
- & Guangwang Liu
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Article
| Open AccessERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions
- Hyunjin Jeong
- , Eun-Hye Hong
- & Hyun-Jeong Ko
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Article
| Open AccessSIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis
- Jianxin Mao
- , Di Wang
- & Zhuojing Luo
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Article
| Open AccessCatecholamine induces Kupffer cell apoptosis via growth differentiation factor 15 in alcohol-associated liver disease
- Hee-Hoon Kim
- , Young-Ri Shim
- & Won-Il Jeong
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Article
| Open AccessMitochondrial citrate accumulation drives alveolar epithelial cell necroptosis in lipopolysaccharide-induced acute lung injury
- Hui-Hui Yang
- , Hui-Ling Jiang
- & Cha-Xiang Guan
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Article
| Open AccessAZIN1 RNA editing alters protein interactions, leading to nuclear translocation and worse outcomes in prostate cancer
- Aram Ghalali
- , Liangzhe Wang
- & Michael S. Rogers
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Article
| Open AccessActivating SIRT3 in peritoneal mesothelial cells alleviates postsurgical peritoneal adhesion formation by decreasing oxidative stress and inhibiting the NLRP3 inflammasome
- Tianli Shen
- , Yunhua Wu
- & Xuqi Li
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Article
| Open AccessPan-Src kinase inhibitor treatment attenuates diabetic kidney injury via inhibition of Fyn kinase-mediated endoplasmic reticulum stress
- Debra Dorotea
- , Songling Jiang
- & Hunjoo Ha
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Article
| Open AccessLeukocyte invasion of the brain after peripheral trauma in zebrafish (Danio rerio)
- Xiang-Ke Chen
- , Joseph Shiu-Kwong Kwan
- & Raymond Chuen-Chung Chang
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Article
| Open AccessThe CDK1/TFCP2L1/ID2 cascade offers a novel combination therapy strategy in a preclinical model of bladder cancer
- Jinbeom Heo
- , Jinyoung Lee
- & Dong-Myung Shin
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| Open AccessHyaluronan synthase 2, a target of miR-200c, promotes carbon tetrachloride-induced acute and chronic liver inflammation via regulation of CCL3 and CCL4
- Sun Myoung Kim
- , Ga Yeon Song
- & Ekihiro Seki
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Review Article
| Open AccessImmunomodulatory functional foods and their molecular mechanisms
- Jae Hwan Kim
- , Da Hyun Kim
- & Sanguine Byun
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Article
| Open AccessAn unusual nicotinamide derivative, 4-pyridone-3-carboxamide ribonucleoside (4PYR), is a novel endothelial toxin and oncometabolite
- Paulina Mierzejewska
- , Michal Kunc
- & Ewa Maria Slominska
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| Open AccessSynergistic cycles of protease activity and inflammation via PPARγ degradation in chronic obstructive pulmonary disease
- Nakwon Kwak
- , Kyoung-Hee Lee
- & Chul-Gyu Yoo
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Article
| Open AccessCereblon contributes to the development of pulmonary fibrosis via inactivation of adenosine monophosphate-activated protein kinase α1
- Hyo Jae Kang
- , Kyung Jin Lee
- & Kyoung-Hee Lee
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Article
| Open AccessThe arachidonic acid metabolite 11,12-epoxyeicosatrienoic acid alleviates pulmonary fibrosis
- Hak Su Kim
- , Su-Jin Moon
- & Jin Woo Song
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Review Article
| Open AccessInnate immune sensing of coronavirus and viral evasion strategies
- Yusuke Kasuga
- , Baohui Zhu
- & Ji-Seung Yoo
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Review Article
| Open AccessSevere fever with thrombocytopenia syndrome virus: emerging novel phlebovirus and their control strategy
- Mark Anthony Casel
- , Su Jin Park
- & Young Ki Choi
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Review Article
| Open AccessOncogenic super-enhancer formation in tumorigenesis and its molecular mechanisms
- Qunying Jia
- , Shuhua Chen
- & Faqing Tang
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Review Article
| Open AccessPathogenic diversity of RNA variants and RNA variation-associated factors in cancer development
- Hee Doo Yang
- & Suk Woo Nam
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Review Article
| Open AccessUltrafine particles: unique physicochemical properties relevant to health and disease
- Hyouk-Soo Kwon
- , Min Hyung Ryu
- & Christopher Carlsten
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Review Article
| Open AccessThe impact of bacteria-derived ultrafine dust particles on pulmonary diseases
- Jinho Yang
- , Eun Kyoung Kim
- & Yoon-Keun Kim
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Article
| Open AccessPreterm birth is associated with epigenetic programming of transgenerational hypertension in mice
- Laurence Dumeige
- , Mélanie Nehlich
- & Laetitia Martinerie
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Article
| Open AccessGadd45β promotes regeneration after injury through TGFβ-dependent restitution in experimental colitis
- Jung Hwan Hwang
- , Tae-Hwan Kim
- & Chul-Ho Lee
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Article
| Open AccessTargeting the IL-1β/IL-1Ra pathways for the aggregation of human islet amyloid polypeptide in an ex vivo organ culture system of the intervertebral disc
- Xinghuo Wu
- , Zhiwei Liao
- & Cao Yang
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Article
| Open AccessAnoctamin 1/TMEM16A controls intestinal Cl− secretion induced by carbachol and cholera toxin
- Byeongjun Lee
- , Gyu-Sang Hong
- & Uhtaek Oh
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Article
| Open AccessA brain somatic RHEB doublet mutation causes focal cortical dysplasia type II
- Shanshan Zhao
- , Zhenghui Li
- & Yun-wu Zhang
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Article
| Open AccessMyeloid cell-specific sirtuin 6 deficiency delays wound healing in mice by modulating inflammation and macrophage phenotypes
- Jeung-Hyun Koo
- , Hyun-Young Jang
- & Byung-Hyun Park
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Article
| Open AccessNobiletin ameliorates hepatic ischemia and reperfusion injury through the activation of SIRT-1/FOXO3a-mediated autophagy and mitochondrial biogenesis
- Theodomir Dusabimana
- , So Ra Kim
- & Hwajin Kim
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Article
| Open AccessSIRT1 inhibits monocyte adhesion to the vascular endothelium by suppressing Mac-1 expression on monocytes
- Seung Jin Lee
- , Seung Eun Baek
- & Chi Dae Kim
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Article
| Open AccessDownregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the TGF-β/collagen pathway in preeclampsia
- Xiang-Hong Xu
- , Yuanhui Jia
- & Li-Ping Jin
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| Open AccessEstrogen promotes the onset and development of idiopathic scoliosis via disproportionate endochondral ossification of the anterior and posterior column in a bipedal rat model
- Shuhui Zheng
- , Hang Zhou
- & Caixia Xu
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| Open AccessSpermidine restores dysregulated autophagy and polyamine synthesis in aged and osteoarthritic chondrocytes via EP300
- Pradeep K. Sacitharan
- , Seint Lwin
- & James R. Edwards
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Article
| Open AccessInactivation of Stat3 and crosstalk of miRNA155-5p and FOXO3a contribute to the induction of IGFBP1 expression by beta-elemene in human lung cancer
- Fang Zheng
- , Qing Tang
- & Swei Sunny Hann
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| Open AccessAdenylate kinase potentiates the capsular polysaccharide by modulating Cps2D in Streptococcus pneumoniae D39
- Prachetash Ghosh
- , Truc Thanh Luong
- & Dong-Kwon Rhee
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Article
| Open AccessOverexpression of TFF3 is involved in prostate carcinogenesis via blocking mitochondria-mediated apoptosis
- Jieying Liu
- , So Youn Kim
- & Yeun-Jun Chung
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Article
| Open AccessAccumulation of myeloid lineage cells is mapping out liver fibrosis post injury: a targetable lesion using Ketanserin
- Saeid Amini-Nik
- , Ali-Reza Sadri
- & Marc G. Jeschke