Poster



IFN Signaling

Signaling in the Type I Interferon Antiviral Innate Immune Response

 

Viral infection triggers the production and release of a protein responsible for suppressing further viral replication, killing infected cells and fueling subsequent stages of the immune response. Cells detect virus infection with an array of virus 'sensors', each of which sets off signaling cascades that culminate in interferon secretion and immune activation.

 

This poster shows the networks and components of virus-sensing signaling pathways that facilitate interferon production and the establishment of an antiviral state.



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