A collection of 15 articles that highlight research carried out using the international Collaborative Cross project has been published in Genetics and G3: Genes, Genomes, Genetics. In the past decade, the Collaborative Cross project has developed recombinant inbred lines of mice, each containing a different genomic contribution from eight founder strains. Some papers cover the mapping methodology, and others describe the development and successful application of the Collaborative Cross — and of a related 'Diversity Outbred' resource — to studying the effect of sequence variation on many mouse traits. The traits range from blood pressure or glucose levels to the adverse response to drugs.
ORIGINAL RESEARCH PAPERS
Genetics collection: http://www.genetics.org/site/misc/MouseGeneticResources.xhtml;
G3 collection: http://www.g3journal.org/site/misc/MouseGeneticResources.xhtml.
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Casci, T. Fruits of the Collaborative Cross. Nat Rev Genet 13, 223 (2012). https://doi.org/10.1038/nrg3210
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DOI: https://doi.org/10.1038/nrg3210