Human organs-on-chips for disease modelling, drug development and personalized medicine
This Review summarizes how human organ chip systems have been used to model complex diseases and rare genetic disorders
This Review summarizes how human organ chip systems have been used to model complex diseases and rare genetic disorders
This Review highlights the diversity in sequence composition of disease-related short tandem repeats. The authors discuss how to detect non-canonical motifs in repeat sequences from sequencing data and review the molecular and clinical consequences of sequence composition changes.