●Signalling to and from tight junctions. Matter, K. & Balda, M. S. Nature Reviews Molecular Cell Biology March (2003)

●Splitting vessels: keeping lymph apart from blood. Rafii, S. & Skobe, M. Nature Medicine February (2003) Separation of the blood and lymph systems is essential for their proper function. The authors discuss the recent discovery of two signalling molecules that keep the two vascular systems apart.

●Dissecting dyskeratosis. Meier, U. T. Nature Genetics February (2003) Dyskeratosis is a rare syndrome, which often leads to tumour development and is always fatal. Thomas Meier discusses the molecular pathogenesis of the disease in this News and Views article.

●Mitochondria, AIF and caspases — rivalling for cell death execution. Penninger, J. M. & Kroemer, G. Nature Cell Biology February (2003) This News and Views article discusses recent studies in Caenorhabditis elegans, which question the roles of various components of cell-death pathways.

●Border crossings. Ager, A. Nature 13 February (2003) Inflammatory cells have to get through blood vessels to reach damaged tissue. This News and Views article indicates that the endothelial membrane has an active role in this process.

●More than skin deep. Bolotin, D. & Fuchs, E. Nature 6 February (2003) The News and Views article discusses the role of NF-κB in the promotion of skin cancer.

●Tamoxifen: a most unlikely pioneering medicine. Jordan, V. C. Nature Reviews Drug Discovery March (2003)

●Biotech's twentieth birthday blues. Miska, D. Nature Reviews Drug Discovery March (2003)

●How the ubiquitin-proteasome system controls transcription. Maratani, M. & Tansey, W. P. Nature Reviews Molecular Cell Biology March (2003)

●China's struggle for practical regulations in medical ethics. Doering, O. Nature Reviews Genetics March (2003)