Neuroscience articles from across Nature Portfolio

Neuroscience is a multidisciplinary science that is concerned with the study of the structure and function of the nervous system. It encompasses the evolution, development, cellular and molecular biology, physiology, anatomy and pharmacology of the nervous system, as well as computational, behavioural and cognitive neuroscience.

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News & Views | 20 March 2023

The basics of base sensing
- Scarlet J. Park
- & William W. Ja
Nature Metabolism, 1-2
News & Views | 20 March 2023

Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy

Nature Neuroscience, 1-2
News & Views | 20 March 2023

Oscillations and avalanches coexist in brain networks close to criticality

Nature Computational Science, 1-2

Latest Research and Reviews

Research
22 March 2023 | Open Access

Blocking dPerk in the intestine suppresses neurodegeneration in a Drosophila model of Parkinson’s disease
- Rebeka Popovic
- , Amrita Mukherjee
- & L. Miguel Martins
Cell Death & Disease 14, 206
Research
21 March 2023 | Open Access

Activation of TrkB in Parvalbumin interneurons is required for the promotion of reversal learning in spatial and fear memory by antidepressants
- Elias Jetsonen
- , Giuliano Didio
- & Juzoh Umemori
Neuropsychopharmacology, 1-10
Research
21 March 2023 | Open Access

Multiplex translaminar imaging in the spinal cord of behaving mice

Fluorescence imaging of the spinal cord poses challenges, including depth of imaging. Here the authors describe a custom microscope and chronically implanted microprism that enables multicolor translaminar imaging of sensory and motor evoked activity in behaving mice, and show that spinal astrocytes show sensorimotor program-dependent calcium excitation.
- Pavel Shekhtmeyster
- , Erin M. Carey
- & Axel Nimmerjahn
Nature Communications 14, 1427
Research
21 March 2023 | Open Access

Cocaine induces locomotor sensitization through a dopamine-dependent VTA-mPFC-FrA cortico-cortical pathway in male mice

The prefrontal cortex is involved in cocaine abuse disorders. Here, the authors show that cocaine suppresses frontal association cortex (FrA) in awake mice and induces locomotor sensitization through a dopamine dependent VTA-vmPFC-FrA pathway.
- Lun Wang
- , Min Gao
- & Zhuan Zhou
Nature Communications 14, 1568
Research
21 March 2023 | Open Access

Expression of olfactory receptor genes in non-olfactory tissues in the developing and adult zebrafish
- Dania Jundi
- , Jean-Pierre Coutanceau
- & Elim Hong
Scientific Reports 13, 4651
Research
21 March 2023 | Open Access

Comparing retinotopic maps of children and adults reveals a late-stage change in how V1 samples the visual field

Many properties of human primary visual cortex (V1) are ‘adult-like’ by childhood. Here, using fMRI, the authors show that V1 of children and adults differentially sample the visual field, indicating a late-stage change in cortical organization.
- Marc M. Himmelberg
- , Ekin Tünçok
- & Jonathan Winawer
Nature Communications 14, 1561

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News and Comment

Comments & Opinion | 20 March 2023

In Memoriam—Robert M. A. Hirschfeld, MD, MSc
- Martin B. Keller
Neuropsychopharmacology, 1
News & Views | 20 March 2023

The basics of base sensing

Animals need to be able to evaluate environmental pH. Mechanisms that mediate sour taste and acid sensing have been reported across species, but less is known about the detection of high pH. Mi et al. identify the gene alkaliphile, which encodes a high-pH-gated chloride channel in the gustatory system of flies.
- Scarlet J. Park
- & William W. Ja
Nature Metabolism, 1-2
News & Views | 20 March 2023

Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy

In the brains of patients with epilepsy, apolipoprotein E-mediated lipid transfer from hyperactive neurons to astrocytes results in lipid metabolism reprogramming and formation of lipid-accumulated reactive astrocytes. These astrocytes exacerbate abnormal discharges of neighboring neurons and, in mice, aggravate seizure symptoms, leading to disease progression.

Nature Neuroscience, 1-2
Comments & Opinion | 20 March 2023

Krishna V. Shenoy (1968–2023)
- Mark M. Churchland
- & Paul Nuyujukian
Nature Neuroscience, 1-2
News & Views | 20 March 2023

Oscillations and avalanches coexist in brain networks close to criticality

We propose a minimal and analytically tractable class of neural networks, the adaptive Ising class. By inferring the model’s parameters from resting-state brain activity recordings, we show that scale-specific oscillations and scale-free avalanches can coexist in resting brains close to a non-equilibrium critical point at the onset of self-sustained oscillations.

Nature Computational Science, 1-2
Research Highlights | 17 March 2023

SMN linked to SNARE complex assembly

New findings indicate a role for SMN protein in assembly of the synaptic SNARE complex at neuromuscular junctions, providing insight into mechanisms of pathology in spinal muscular atrophy.
- Katherine Whalley
Nature Reviews Neuroscience, 1

All News & Comment

Neuroscience articles from across Nature Portfolio

Featured

The basics of base sensing

Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy

Oscillations and avalanches coexist in brain networks close to criticality

Latest Research and Reviews

Blocking dPerk in the intestine suppresses neurodegeneration in a Drosophila model of Parkinson’s disease

Activation of TrkB in Parvalbumin interneurons is required for the promotion of reversal learning in spatial and fear memory by antidepressants

Multiplex translaminar imaging in the spinal cord of behaving mice

Cocaine induces locomotor sensitization through a dopamine-dependent VTA-mPFC-FrA cortico-cortical pathway in male mice

Expression of olfactory receptor genes in non-olfactory tissues in the developing and adult zebrafish

Comparing retinotopic maps of children and adults reveals a late-stage change in how V1 samples the visual field

News and Comment

In Memoriam—Robert M. A. Hirschfeld, MD, MSc

The basics of base sensing

Abnormal lipid metabolism shapes astrocyte reactivity in patients with epilepsy

Krishna V. Shenoy (1968–2023)

Oscillations and avalanches coexist in brain networks close to criticality

SMN linked to SNARE complex assembly

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