Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Learning and memory refers to the processes of acquiring, retaining and retrieving information in the central nervous system. It consists of forming stable long-term memories that include declarative (recall of events and facts) and nondeclarative (conditioning, skill learning) forms.
Discriminating threat from safety is critical for humans to navigate their environment. Here, the authors show that neural representations of threat and safety are distributed across brain systems that are robustly decoded across threat paradigms.
A mark test of self-recognition in mice reveals that self-responding ventral CA1 neurons underlie mirror-induced self-directed behaviour and are shaped by social experience with conspecifics.
In mice, localized mutant APP expression in the CA3 hippocampal region leads to progressive network dysfunction and hippocampus-dependent memory deficits.
Neuronal energization and memory formation in the fruit fly are found to be conditioned by the shuttling of alanine between glial cells and neurons. This observation highlights the emerging role of energy metabolism as a driver of tissue function.