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Layer 6 corticothalamic (L6CT) neurons provide feedback that shapes signaling in sensory pathways. Here, authors show that L6CT neurons are bi-directional modulators of thalamocortical signaling, in a manner dependent upon both L6CT magnitude and synchronization
Applying contrast enhancement principles, established within the visual and auditory domain, to thermosensation, reveals that larger temporal contrasts increase the probability of experiencing thermal nociceptive illusions.
Infants with heightened vs. lower likelihood of developing autism spectrum disorder exhibit different functional connectivity patterns in the salience network. These patterns predict sensory and social behaviors at 1 year of age.
Innate fear-like responses are thought to involve the amygdala, but here a tetra-synaptic pathway is identified that mediates odour-evoked innate fear in mice.
Infant attachment to the mother in rodents and monkeys is shown to rely on regulation of hypothalamic oxytocin release by a serotonergic projection from the raphe nucleus.