Featured
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Platelets induce CD39 expression in tumor cells to facilitate tumor metastasis
- Zhaochen Ning
- , Keyan Liu
- & Huabao Xiong
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Article
| Open Access
Immune evasion in lung metastasis of leiomyosarcoma: upregulation of EPCAM inhibits CD8+ T cell infiltration
- Masaya Kanahori
- , Eijiro Shimada
- & Yasuharu Nakashima
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Article |
PTEN-restoration abrogates brain colonisation and perivascular niche invasion by melanoma cells
- Sarah Wang
- , Caroline P. Riedstra
- & Andrew C. Dudley
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Article |
Periostin–TGF-β feedforward loop contributes to tumour-stroma crosstalk in liver metastatic outgrowth of colorectal cancer
- Bin Liu
- , Tiantian Wu
- & Gaoliang Ouyang
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Review Article
| Open Access
Circulating tumour cells in gastrointestinal cancers: food for thought?
- Simran Asawa
- , Manuel Nüesch
- & Nicola Aceto
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Correspondence |
Comment on ‘Use the term “infiltrative” instead of “replacement” when defining histopathological growth pattern in patients with liver cancer’ by Kong B et al.
- Peter Vermeulen
- , Emily Latacz
- & Luc Dirix
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Article
| Open Access
Prognostic impact of extracranial disease control in HER2+ breast cancer-related brain metastases
- Michele Bottosso
- , Gaia Griguolo
- & Maria Vittoria Dieci
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Article |
Efficacy and toxicity of primary re-irradiation for malignant spinal cord compression based on radiobiological modelling: a phase II clinical trial
- Neil D. Wallace
- , Mary T. Dunne
- & Pierre G. Thirion
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Article |
Targeted exome-based predictors of patterns of progression of colorectal liver metastasis after percutaneous thermal ablation
- Iwan Paolucci
- , Yuan-Mao Lin
- & Bruno C. Odisio
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Article |
YTHDF2-mediated FGF14-AS2 decay promotes osteolytic metastasis of breast cancer by enhancing RUNX2 mRNA translation
- Ming Zhang
- , Jue Wang
- & Changyan Ma
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Article |
A liquid biopsy signature predicts lymph node metastases in T1 oesophageal squamous cell carcinoma: implications for precision treatment strategy
- Liyan Xue
- , Zitong Zhao
- & Yongmei Song
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Perspective |
Extruded small extracellular vesicles: splinters of circulating tumour cells may promote cancer metastasis?
- Yuan Wan
- , Yi-Qiu Xia
- & Si-Yang Zheng
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Article
| Open Access
Non-canonical EphA2 activation underpins PTEN-mediated metastatic migration and poor clinical outcome in prostate cancer
- Ashwin Sachdeva
- , Claire A. Hart
- & Noel Clarke
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Editorial |
New insights into the unique nature of colorectal cancer peritoneal metastases—rethinking HIPEC
- Robert G. Ramsay
- & Michael Flood
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Perspective
| Open Access
Steering decision making by terminology: oligometastatic versus argometastatic
- Petr Szturz
- & Jan B. Vermorken
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Review Article
| Open Access
Recent insights into the effects of metabolism on breast cancer cell dormancy
- Sara Bartlome
- & Catherine Cecilia Berry
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Review Article |
Histopathological growth patterns of liver metastasis: updated consensus guidelines for pattern scoring, perspectives and recent mechanistic insights
- Emily Latacz
- , Diederik Höppener
- & Peter B. Vermeulen
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Article
| Open Access
Resectability, conversion, metastasectomy and outcome according to RAS and BRAF status for metastatic colorectal cancer in the prospective RAXO study
- Aki Uutela
- , Emerik Osterlund
- & Pia Osterlund
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Review Article
| Open Access
Functional analysis of circulating tumour cells: the KEY to understand the biology of the metastatic cascade
- Zahra Eslami-S
- , Luis Enrique Cortés-Hernández
- & Catherine Alix-Panabières
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Article |
Aryl-hydrocarbon receptor-interacting protein regulates tumorigenic and metastatic properties of colorectal cancer cells driving liver metastasis
- Guillermo Solís-Fernández
- , Ana Montero-Calle
- & Rodrigo Barderas
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Article
| Open Access
VIVA1: a more invasive subclone of MDA-MB-134VI invasive lobular carcinoma cells with increased metastatic potential in xenograft models
- Victoria Allen
- , Josée Coulombe
- & Christina L. Addison
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Article |
CCT5 induces epithelial-mesenchymal transition to promote gastric cancer lymph node metastasis by activating the Wnt/β-catenin signalling pathway
- Yun Li
- , Chenying Liu
- & Han Tian
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Article |
Immune biomarkers and response to checkpoint inhibition of BRAFV600 and BRAF non-V600 altered lung cancers
- Yonina R. Murciano-Goroff
- , Terry Pak
- & Michael Offin
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Article |
Mitochondrial matrix protein C14orf159 attenuates colorectal cancer metastasis by suppressing Wnt/β-catenin signalling
- Kenji Ohshima
- , Ryo Oi
- & Eiichi Morii
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Review Article |
ESR1 mutations and therapeutic resistance in metastatic breast cancer: progress and remaining challenges
- Sarah K. Herzog
- & Suzanne A. W. Fuqua
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Article |
Atorvastatin facilitates chemotherapy effects in metastatic triple-negative breast cancer
- Juan Luis Gomez Marti
- , Colin H. Beckwitt
- & Alan Wells
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Article
| Open Access
Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone
- Sanne ten Hoorn
- , Dirkje W. Sommeijer
- & Louis Vermeulen
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Review Article |
Breast cancer brain metastasis: insight into molecular mechanisms and therapeutic strategies
- Yajie Wang
- , Fangzhou Ye
- & Qifeng Yang
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Article
| Open Access
S100P contributes to promoter demethylation and transcriptional activation of SLC2A5 to promote metastasis in colorectal cancer
- Mingdao Lin
- , Yuan Fang
- & Haijun Deng
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Article
| Open Access
A preclinical pipeline to evaluate migrastatics as therapeutic agents in metastatic melanoma
- Oscar Maiques
- , Bruce Fanshawe
- & Gilbert O. Fruhwirth
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Review Article |
Towards decoding the coupled decision-making of metabolism and epithelial-to-mesenchymal transition in cancer
- Dongya Jia
- , Jun Hyoung Park
- & Herbert Levine
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Review Article
| Open Access
Breast cancer as an example of tumour heterogeneity and tumour cell plasticity during malignant progression
- Fabiana Lüönd
- , Stefanie Tiede
- & Gerhard Christofori
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Article
| Open Access
CD8+ T cells inhibit metastasis and CXCL4 regulates its function
- Robiya Joseph
- , Rama Soundararajan
- & Sendurai A. Mani
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Article |
Aspirin reduces the incidence of metastasis in a pre-clinical study of Braf mutant serrated colorectal neoplasia
- Alexandra M. Kane
- , Cheng Liu
- & Vicki L. J. Whitehall
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Review Article |
Bone marrow niches in the regulation of bone metastasis
- Fenfang Chen
- , Yujiao Han
- & Yibin Kang
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Review Article
| Open Access
Cancer metastasis as a non-healing wound
- Matthew Deyell
- , Christopher S. Garris
- & Ashley M. Laughney
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Article
| Open Access
Eight years of experience with vismodegib for advanced and multiple basal cell carcinoma patients in the Netherlands: a retrospective cohort study
- Babette J. A. Verkouteren
- , Marlies Wakkee
- & Klara Mosterd
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Article
| Open Access
EMTome: a resource for pan-cancer analysis of epithelial-mesenchymal transition genes and signatures
- Suhas V. Vasaikar
- , Abhijeet P. Deshmukh
- & Sendurai A. Mani
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Comment |
Phosphatase, pseudo-phosphatase, or both? Understanding PRL oncogenicity
- Kalle Gehring
- & Hiroaki Miki
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Review Article
| Open Access
Endocytosis: a pivotal pathway for regulating metastasis
- Imran Khan
- & Patricia S. Steeg
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Review Article
| Open Access
TRAIL receptor-induced features of epithelial-to-mesenchymal transition increase tumour phenotypic heterogeneity: potential cell survival mechanisms
- Ludovic Peyre
- , Mickael Meyer
- & Jérémie Roux
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Review Article
| Open Access
Squeezing through the microcirculation: survival adaptations of circulating tumour cells to seed metastasis
- Julia Perea Paizal
- , Sam H. Au
- & Chris Bakal
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Review Article
| Open Access
Treatment strategies for breast cancer brain metastases
- Caroline Bailleux
- , Lauriane Eberst
- & Thomas Bachelot
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Article
| Open Access
CDX2 inhibits epithelial–mesenchymal transition in colorectal cancer by modulation of Snail expression and β-catenin stabilisation via transactivation of PTEN expression
- Junhui Yu
- , Shan Li
- & Xuejun Sun
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Review Article
| Open Access
The lingering mysteries of metastatic recurrence in breast cancer
- Alessandra I. Riggio
- , Katherine E. Varley
- & Alana L. Welm
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Review Article
| Open Access
Metastasis-directed therapy for oligometastasis and beyond
- Thomas H. Beckham
- , T. Jonathan Yang
- & C. Jillian Tsai
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Review Article
| Open Access
Metastasis: crosstalk between tissue mechanics and tumour cell plasticity
- Bircan Coban
- , Cecilia Bergonzini
- & Erik H. J. Danen
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Review Article
| Open Access
Genomic control of metastasis
- Saroor A. Patel
- , Paulo Rodrigues
- & Sakari Vanharanta
Assessing the effect of metastasis-directed therapy in oligometastatic disease using the restricted mean survival time
The vascular outsiders