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Cellular and Molecular Biology

Comment on ‘Use the term “infiltrative” instead of “replacement” when defining histopathological growth pattern in patients with liver cancer’ by Kong B et al.

British Journal of Cancer volume 128, pages 705–706 (2023)Cite this article

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Dear Editor,

We are pleased to be able to comment on the correspondence by Kong et al. who suggest using the term “infiltrative growth pattern” instead of “replacement growth pattern” [1] when referring to one of the morphologically well-characterised histopathological growth patterns of liver metastases, as discussed in the recently published second version of the international guidelines to assess these patterns [2].

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Fig. 1: Haematoxylin- and eosin-stained tissue section of a breast cancer liver metastasis with a replacement histopathological growth pattern (scale bar: 50 µm).

References

  1. Kong B, Zhang Q, Zhang G. Use the term “infiltrative” instead of “replacement” when defining histopathological growth pattern in patients with liver cancer. Br J Cancer. 2023 (this issue).

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Funding

The research projects of PV and LD are funded by the Koning Boudewijnstichting (King Baudouin Foundation)—Fonds Oncologie Augustinus.

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Authors and Affiliations

  1. Translational Cancer Research Unit, GZA Hospital Sint-Augustinus & University of Antwerp, Antwerp, Belgium

    Peter Vermeulen, Emily Latacz, Laura Hendrickx, Michelle Van den Hauwe & Luc Dirix

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  1. Peter Vermeulen
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  2. Emily Latacz
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  3. Laura Hendrickx
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  4. Michelle Van den Hauwe
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  5. Luc Dirix
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All authors contributed equally to writing the manuscript.

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Correspondence to Peter Vermeulen.

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Vermeulen, P., Latacz, E., Hendrickx, L. et al. Comment on ‘Use the term “infiltrative” instead of “replacement” when defining histopathological growth pattern in patients with liver cancer’ by Kong B et al.. Br J Cancer 128, 705–706 (2023). https://doi.org/10.1038/s41416-023-02173-6

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