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| Open AccessTowards water-soluble [60]fullerenes for the delivery of siRNA in a prostate cancer model
- Julia Korzuch
- , Monika Rak
- & Maciej Serda
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| Open AccessOuter membrane and phospholipid composition of the target membrane affect the antimicrobial potential of first- and second-generation lipophosphonoxins
- Klára Látrová
- , Noemi Havlová
- & Gabriela Mikušová
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| Open AccessRepurposing potential of posaconazole and grazoprevir as inhibitors of SARS-CoV-2 helicase
- Syed Hani Abidi
- , Nahlah Makki Almansour
- & Syed Ali
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| Open AccessMolecular docking analysis and evaluation of the antibacterial and antioxidant activities of the constituents of Ocimum cufodontii
- Muhdin Aliye
- , Aman Dekebo
- & Yadessa Melaku
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| Open AccessGeneration of a chemical genetic model for JAK3
- Judit Remenyi
- , Rangeetha Jayaprakash Naik
- & J. Simon C. Arthur
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| Open AccessStudy on effects of sweating treatment and different drying methods on the quality of Gentianae macrophyllae Radix
- Qianliang Chen
- , Zhangyan Shi
- & Hehe Hu
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| Open AccessElucidating direct kinase targets of compound Danshen dropping pills employing archived data and prediction models
- Tongxing Wang
- , Lu Liang
- & Yunhui Hu
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| Open AccessInterbase-FRET binding assay for pre-microRNAs
- Mattias Bood
- , Anna Wypijewska del Nogal
- & Morten Grøtli
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| Open AccessHDAC2 targeting stabilizes the CoREST complex in renal tubular cells and protects against renal ischemia/reperfusion injury
- David D. Aufhauser Jr.
- , Paul Hernandez
- & Matthew H. Levine
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| Open AccessTrienone analogs of curcuminoids induce fetal hemoglobin synthesis via demethylation at Gγ-globin gene promoter
- Khanita Nuamsee
- , Thipphawan Chuprajob
- & Saovaros Svasti
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| Open AccessUltrasensitive nucleic acid detection based on phosphorothioated hairpin-assisted isothermal amplification
- Yujin Jung
- , Jayeon Song
- & Hyun Gyu Park
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| Open AccessChemical characterization (LC–MS–ESI), cytotoxic activity and intracellular localization of PAMAM G4 in leukemia cells
- R. Flores-Mejía
- , M. J. Fragoso-Vázquez
- & J. Correa-Basurto
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| Open AccessEnantiomers of 2-methylglutamate and 2-methylglutamine selectively impact mouse brain metabolism and behavior
- Adam M. Wawro
- , Chandresh R. Gajera
- & Thomas J. Montine
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| Open AccessMultisubstituted pyrimidines effectively inhibit bacterial growth and biofilm formation of Staphylococcus aureus
- Riccardo Provenzani
- , Paola San-Martin-Galindo
- & Jari Yli-Kauhaluoma
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| Open AccessIdentification of novel inhibitors of Keap1/Nrf2 by a promising method combining protein–protein interaction-oriented library and machine learning
- Yugo Shimizu
- , Tomoki Yonezawa
- & Kazuyoshi Ikeda
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| Open AccessComputational drug repurposing study elucidating simultaneous inhibition of entry and replication of novel corona virus by Grazoprevir
- Santosh Kumar Behera
- , Nazmina Vhora
- & Alok Jain
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| Open AccessDiscovery of novel antituberculosis agents among 3-phenyl-5-(1-phenyl-1H-[1,2,3]triazol-4-yl)-[1,2,4]oxadiazole derivatives targeting aminoacyl-tRNA synthetases
- Mariia Yu. Rybak
- , Anatoliy O. Balanda
- & Galyna P. Volynets
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| Open AccessAnti-estrogenic and anti-aromatase activities of citrus peels major compounds in breast cancer
- Dina M. El-Kersh
- , Shahira M. Ezzat
- & Mohey M. Elmazar
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| Open AccessIn vivo uptake of antisense oligonucleotide drugs predicted by ab initio quantum mechanical calculations
- Henrik Frydenlund Hansen
- , Nanna Albaek
- & Troels Koch
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| Open AccessNon-specific interactions of antibody-oligonucleotide conjugates with living cells
- Victor Lehot
- , Isabelle Kuhn
- & Alain Wagner
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| Open AccessEnteric reabsorption processes and their impact on drug pharmacokinetics
- Manuel Ibarra
- , Iñaki F. Trocóniz
- & Pietro Fagiolino
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| Open AccessDrug design and repurposing with DockThor-VS web server focusing on SARS-CoV-2 therapeutic targets and their non-synonym variants
- Isabella A. Guedes
- , Leon S. C. Costa
- & Laurent E. Dardenne
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| Open AccessPreparation and application of a thidiazuron·diuron ultra-low-volume spray suitable for plant protection unmanned aerial vehicles
- Qin Liu
- , Kun Wei
- & Wei Xue
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| Open AccessDevelopment of antitumor biguanides targeting energy metabolism and stress responses in the tumor microenvironment
- Takayuki Sakai
- , Yoshiyuki Matsuo
- & Hideko Nagasawa
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| Open AccessDevelopment of water-soluble prodrugs of the bisdioxopiperazine topoisomerase IIβ inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity
- Hana Bavlovič Piskáčková
- , Hana Jansová
- & Petra Štěrbová-Kovaříková
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| Open AccessPterostilbene inhibits gallbladder cancer progression by suppressing the PI3K/Akt pathway
- Chenhao Tong
- , Yali Wang
- & Baochun Lu
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| Open AccessNanocomposite-based dual enzyme system for broad-spectrum scavenging of reactive oxygen species
- Marko Pavlovic
- , Szabolcs Muráth
- & Istvan Szilagyi
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| Open AccessThe assessment of the usability of selected instrumental techniques for the elemental analysis of biomedical samples
- Karolina Planeta
- , Aldona Kubala-Kukus
- & Joanna Chwiej
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| Open AccessImidazopyridine hydrazone derivatives exert antiproliferative effect on lung and pancreatic cancer cells and potentially inhibit receptor tyrosine kinases including c-Met
- Tahereh Damghani
- , Fatemeh Moosavi
- & Omidreza Firuzi
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| Open AccessIdentification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2
- Ewelina Weglarz-Tomczak
- , Jakub M. Tomczak
- & Stanley Brul
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| Open AccessThe antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957
- Celia Miguel-Blanco
- , James M. Murithi
- & Michael J. Delves
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| Open AccessMechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles
- Diogo Henrique Kita
- , Nathalie Guragossian
- & Marc Le Borgne
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| Open AccessA high-throughput cell-based assay pipeline for the preclinical development of bacterial DsbA inhibitors as antivirulence therapeutics
- Anthony D. Verderosa
- , Rabeb Dhouib
- & Makrina Totsika
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| Open AccessPotential repurposing of four FDA approved compounds with antiplasmodial activity identified through proteome scale computational drug discovery and in vitro assay
- Bakary N’tji Diallo
- , Tarryn Swart
- & Kevin Lobb
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| Open AccessSynthesis and tumour cell uptake studies of gadolinium(III)–phosphonium complexes
- Andrew J. Hall
- , Amy G. Robertson
- & Louis M. Rendina
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| Open AccessIdentification of a new cannabidiol n-hexyl homolog in a medicinal cannabis variety with an antinociceptive activity in mice: cannabidihexol
- Pasquale Linciano
- , Cinzia Citti
- & Giuseppe Cannazza
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| Open AccessFluorescent ligands for dopamine D2/D3 receptors
- Anni Allikalt
- , Nirupam Purkayastha
- & Dorothee Weikert
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| Open AccessHigh pressure assisted synthetic approach for novel 6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-b]pyridine and 5,6-dihydrobenzo[h]quinoline derivatives and their assessment as anticancer agents
- Haider Behbehani
- , Fatemah A. Aryan
- & Hamada Mohamed Ibrahim
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| Open AccessHigh-throughput screening to discover inhibitors of the CarD·RNA polymerase protein–protein interaction in Mycobacterium tuberculosis
- Maxwell A. Stefan
- , Glory M. Velazquez
- & George A. Garcia
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| Open AccessRepurposing of FDA approved ring systems through bi-directional target-ring system dual screening
- Surendra Kumar
- , Cheongyun Jang
- & Mi-hyun Kim
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| Open AccessInsights into the chemistry of the amphibactin–metal (M3+) interaction and its role in antibiotic resistance
- Vidya Kaipanchery
- , Anamika Sharma
- & Beatriz G. de la Torre
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| Open AccessTargeting the coronavirus SARS-CoV-2: computational insights into the mechanism of action of the protease inhibitors lopinavir, ritonavir and nelfinavir
- Giovanni Bolcato
- , Maicol Bissaro
- & Stefano Moro
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| Open AccessA chromatographic approach to development of 5-aminosalicylate/folic acid fixed-dose combinations for treatment of Crohn’s disease and ulcerative colitis
- Mario-Livio Jeličić
- , Edvin Brusač
- & Ana Mornar
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| Open AccessSynthesis of novel cytotoxic tetracyclic acridone derivatives and study of their molecular docking, ADMET, QSAR, bioactivity and protein binding properties
- Rajkumar Veligeti
- , Rajesh Bagepalli Madhu
- & Grigory Vasilievich Zyryanov
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| Open AccessTetrahydrobiopterin prevents chronic ischemia-related lower urinary tract dysfunction through the maintenance of nitric oxide bioavailability
- Hidenori Akaihata
- , Junya Hata
- & Yoshiyuki Kojima
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| Open AccessSynergistic effects of combinatorial chitosan and polyphenol biomolecules on enhanced antibacterial activity of biofunctionalized silver nanoparticles
- Niloufar Hajarian Rezazadeh
- , Foad Buazar
- & Soheila Matroodi
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| Open AccessMeasuring dissolution profiles of single controlled-release drug pellets
- Heran C. Bhakta
- , Jessica M. Lin
- & William H. Grover
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| Open AccessIn vitro and in vivo BNCT investigations using a carborane containing sulfonamide targeting CAIX epitopes on malignant pleural mesothelioma and breast cancer cells
- Diego Alberti
- , Alessia Michelotti
- & Simonetta Geninatti Crich
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| Open AccessSearching for target-specific and multi-targeting organics for Covid-19 in the Drugbank database with a double scoring approach
- Natarajan Arul Murugan
- , Sanjiv Kumar
- & Vaibhav Srivastava