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Original Article
| Open AccessEndometrial cancer-associated mutants of SPOP are defective in regulating estrogen receptor-α protein turnover
- P Zhang
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- & C Wang
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Original Article
| Open AccessMitochondrial DNA copy number is regulated by DNA methylation and demethylation of POLGA in stem and cancer cells and their differentiated progeny
- W Lee
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Original Article
| Open AccessAngelman syndrome-associated ubiquitin ligase UBE3A/E6AP mutants interfere with the proteolytic activity of the proteasome
- V Tomaić
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Original Article
| Open AccessThe malignant phenotype in breast cancer is driven by eIF4A1-mediated changes in the translational landscape
- A Modelska
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Original Article
| Open AccessA tight control of Rif1 by Oct4 and Smad3 is critical for mouse embryonic stem cell stability
- P Li
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Original Article
| Open AccessDecreased H3K27 and H3K4 trimethylation on mortal chromosomes in distributed stem cells
- Y H Huh
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Original Article
| Open AccessEnhancing mammary differentiation by overcoming lineage-specific epigenetic modification and signature gene expression of fibroblast-derived iPSCs
- Y Li
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Original Article
| Open AccessDNA methylation and differential gene regulation in photoreceptor cell death
- P Farinelli
- , A Perera
- & P A R Ekström
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Original Article
| Open AccessCDK1 plays an important role in the maintenance of pluripotency and genomic stability in human pluripotent stem cells
- I Neganova
- , K Tilgner
- & M Lako
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Original Article
| Open AccessHDAC8 and STAT3 repress BMF gene activity in colon cancer cells
- Y Kang
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Original Article
| Open AccessBiological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice
- L Ruan
- , Z Zhang
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Correspondence
| Open AccessAML cells carrying NPM1 mutation are resistant to nucleophosmin displacement from nucleoli caused by the G-quadruplex ligand TmPyP4
- A De Cola
- , L Pietrangelo
- & L Federici
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Original Article
| Open AccessRestoration of miR-101 suppresses lung tumorigenesis through inhibition of DNMT3a-dependent DNA methylation
- F Yan
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- & S Liu
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Original Article
| Open AccessInfluence of relative NK–DC abundance on placentation and its relation to epigenetic programming in the offspring
- N Freitag
- , M V Zwier
- & S M Blois
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Correspondence
| Open AccessA new posttranslational regulation of REDD1/DDIT4 through cleavage by caspase 3 modifies its cellular function
- A Puissant
- , N Fenouille
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Original Article
| Open AccessProlyl-4-hydroxylase 2 enhances hypoxia-induced glioblastoma cell death by regulating the gene expression of hypoxia-inducible factor-α
- W Sun
- , W Jelkmann
- & R Depping
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Original Article
| Open AccessThe zinc sensing receptor, ZnR/GPR39, controls proliferation and differentiation of colonocytes and thereby tight junction formation in the colon
- L Cohen
- , I Sekler
- & M Hershfinkel
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Original Article
| Open AccessDYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson’s disease
- M J Barallobre
- , C Perier
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Correspondence
| Open AccessCREAM: a database for chemotherapy resistance-associated miRSNP
- E Dai
- , Y Lv
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Review
| Open AccessSystems biology approaches to develop innovative strategies for lung cancer therapy
- K Viktorsson
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Original Article
| Open AccessLiver kinase B1 regulates the centrosome via PLK1
- K Werle
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Original Article
| Open AccessMutation of a Nopp140 gene dao-5 alters rDNA transcription and increases germ cell apoptosis in C. elegans
- C-C Lee
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Original Article
| Open AccessHomozygous mutation of MTPAP causes cellular radiosensitivity and persistent DNA double-strand breaks
- N T Martin
- , K Nakamura
- & P Concannon
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Original Article
| Open AccessUnequal prognostic potentials of p53 gain-of-function mutations in human cancers associate with drug-metabolizing activity
- J Xu
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Original Article
| Open AccessGlycogen synthase kinase 3β represses MYOGENIN function in alveolar rhabdomyosarcoma
- M G Dionyssiou
- , S Ehyai
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Original Article
| Open AccessExpression of base excision repair key factors and miR17 in familial and sporadic breast cancer
- S De Summa
- , R Pinto
- & S Tommasi
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Original Article
| Open AccessGLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis
- E Pantazi
- , E Gemenetzidis
- & M P Philpott
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Original Article
| Open AccessPATZ1 interacts with p53 and regulates expression of p53-target genes enhancing apoptosis or cell survival based on the cellular context
- T Valentino
- , D Palmieri
- & M Fedele
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Original Article
| Open AccessGene miles-apart is required for formation of otic vesicle and hair cells in zebrafish
- Z-y Hu
- , Q-y Zhang
- & J-p Zhang
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Original Article
| Open AccessLHX6 acts as a novel potential tumour suppressor with epigenetic inactivation in lung cancer
- W-b Liu
- , X Jiang
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Original Article
| Open AccessImplication of transcriptional repression in compound C-induced apoptosis in cancer cells
- R Y Dai
- , X F Zhao
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Original Article
| Open AccessThe epigenetic modifier trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial–mesenchymal transition of lens epithelial cells
- X Chen
- , W Xiao
- & Y Liu
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Original Article
| Open AccessTranslational control in the stress adaptive response of cancer cells: a novel role for the heat shock protein TRAP1
- D S Matassa
- , M R Amoroso
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Original Article
| Open AccessA
NANOS3 mutation linked to protein degradation causes premature ovarian insufficiency- X Wu
- , B Wang
- & Y Xu
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Original Article
| Open AccessDexamethasone shifts bone marrow stromal cells from osteoblasts to adipocytes by C/EBPalpha promoter methylation
- J Li
- , N Zhang
- & X Zhang
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Original Article
| Open AccessInteraction of Sirt3 with OGG1 contributes to repair of mitochondrial DNA and protects from apoptotic cell death under oxidative stress
- Y Cheng
- , X Ren
- & J-M Yang
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Original Article
| Open AccessThe role of thioredoxin 1 in the mycophenolic acid-induced apoptosis of insulin-producing cells
- K H Huh
- , Y Cho
- & Y S Kim
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Original Article
| Open AccessHuman mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy
- J C Estrada
- , Y Torres
- & A Bernad
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Original Article
| Open AccessCPEB1, a histone-modified hypomethylated gene, is regulated by miR-101 and involved in cell senescence in glioma
- L Xiaoping
- , Y Zhibin
- & L Guiyuan
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Original Article
| Open AccessBNIP3 acts as transcriptional repressor of death receptor-5 expression and prevents TRAIL-induced cell death in gliomas
- T R Burton
- , E S Henson
- & S B Gibson
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Original Article
| Open AccessMenin mediates epigenetic regulation via histone H3 lysine 9 methylation
- Y-J Yang
- , T-Y Song
- & E-J Cho
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Original Article
| Open AccessCaspase-3 cleaves hnRNP K in erythroid differentiation
- I S Naarmann-de Vries
- , H Urlaub
- & A Ostareck-Lederer
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Original Article
| Open AccessHuman VRK2 modulates apoptosis by interaction with Bcl-xL and regulation of BAX gene expression
- D M Monsalve
- , T Merced
- & P A Lazo
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Original Article
| Open AccessHDAC inhibitors induce tumor-cell-selective pro-apoptotic transcriptional responses
- J E Bolden
- , W Shi
- & R W Johnstone
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Original Article
| Open AccessEVER2 protein binds TRADD to promote TNF-α-induced apoptosis
- G Gaud
- , D Guillemot
- & F Vuillier
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Original Article
| Open AccessA meta-analysis of cancer risk associated with the TP53 intron 3 duplication polymorphism (rs17878362): geographic and tumor-specific effects
- C Sagne
- , V Marcel
- & J Hall
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Original Article
| Open AccessConformational altered p53 affects neuronal function: relevance for the response to toxic insult and growth-associated protein 43 expression
- L Buizza
- , C Prandelli
- & D Uberti
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Original Article
| Open AccessEpigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma
- N Syed
- , J Langer
- & T Crook
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Original Article
| Open AccessSelective glucocorticoid receptor translational isoforms reveal glucocorticoid-induced apoptotic transcriptomes
- I Wu
- , S C Shin
- & N Z Lu
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