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| Open AccessEnhancer of zeste homolog 2 promotes renal fibrosis after acute kidney injury by inducing epithelial-mesenchymal transition and activation of M2 macrophage polarization
- Xun Zhou
- , Hui Chen
- & Na Liu
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Article
| Open AccessDNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath
- Huan Wu
- , Yiyuan Liu
- & Yunxia Cao
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Article
| Open AccessPSMA1 mediates tumor progression and poor prognosis of gastric carcinoma by deubiquitinating and stabilizing TAZ
- Qinyu Yang
- , Ying Lu
- & Xu Shu
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Article
| Open AccessNuclear factor I-C disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects
- Wanqi Huang
- , Tianchu Huang
- & Zhengwei Yuan
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Article
| Open AccessEssential role of zyxin in platelet biogenesis and glycoprotein Ib-IX surface expression
- Rong Yan
- , Xinxin Ge
- & Kesheng Dai
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Article
| Open AccessIdentification of a germline CSPG4 variation in a family with neurofibromatosis type 1-like phenotype
- Zhuanli Bai
- , Yiping Qu
- & Peng Hou
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Article
| Open AccessNon-canonical role of wild-type SEC23B in the cellular stress response pathway
- Lamis Yehia
- , Darren Liu
- & Charis Eng
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Article
| Open AccessThe rs7911488-T allele promotes the growth and metastasis of colorectal cancer through modulating miR-1307/PRRX1
- Man Yang
- , Xinchang Liu
- & Weipeng Wang
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Article
| Open AccessHfm1 participates in Golgi-associated spindle assembly and division in mouse oocyte meiosis
- Huiyuan Wang
- , Chenyi Zhong
- & Jie Wu
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Article
| Open AccessFTSJ1 regulates tRNA 2ʹ-O-methyladenosine modification and suppresses the malignancy of NSCLC via inhibiting DRAM1 expression
- Qihan He
- , Lin Yang
- & Rihong Zhai
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Article
| Open AccessDeletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity
- Hongshun Wang
- , Changsong Lin
- & Xin Cao
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Article
| Open AccessLnc SMAD5-AS1 as ceRNA inhibit proliferation of diffuse large B cell lymphoma via Wnt/β-catenin pathway by sponging miR-135b-5p to elevate expression of APC
- Chen-Chen Zhao
- , Yang Jiao
- & Gu Kang-Sheng
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Original Article
| Open AccessThe spontaneous differentiation and chromosome loss in iPSCs of human trisomy 18 syndrome
- Ting Li
- , Hanzhi Zhao
- & Dongmei Lai
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Original Article
| Open AccessBCR–ABL1-induced downregulation of WASP in chronic myeloid leukemia involves epigenetic modification and contributes to malignancy
- Welbert O Pereira
- , Daniel D De Carvalho
- & Gustavo P Amarante-Mendes
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Original Article
| Open AccessAdropin deficiency worsens HFD-induced metabolic defects
- Shi Chen
- , Kai Zeng
- & Feng Gao
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Original Article
| Open AccessConcomitant epigenetic targeting of LSD1 and HDAC synergistically induces mitochondrial apoptosis in rhabdomyosarcoma cells
- Tinka Haydn
- , Eric Metzger
- & Simone Fulda
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Original Article
| Open AccessIn vitro expansion impaired the stemness of early passage mesenchymal stem cells for treatment of cartilage defects
- Tongmeng Jiang
- , Guojie Xu
- & Xingdong Zhang
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Original Article
| Open AccessCALCB splice region pathogenic variants leading to plasma cell neurotropic enrichment in type 1 autoimmune pancreatitis
- Qi-cai Liu
- , Falin Chen
- & Xin-hua Lin
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Original Article
| Open AccessAttenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model
- Kit I Tong
- , Kazushige Ota
- & Hitoshi Okada
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Original Article
| Open AccessOncogenic microtubule hyperacetylation through BEX4-mediated sirtuin 2 inhibition
- Jin-Kwan Lee
- , Janet Lee
- & Chang-Woo Lee
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Original Article
| Open AccessMitochondrial dysfunction in an Opa1Q285STOP mouse model of dominant optic atrophy results from Opa1 haploinsufficiency
- Y Kushnareva
- , Y Seong
- & D D Newmeyer
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Review
| Open AccessATP2C1 gene mutations in Hailey–Hailey disease and possible roles of SPCA1 isoforms in membrane trafficking
- M Micaroni
- , G Giacchetti
- & L Federici
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Original Article
| Open AccessPrediction of disease–gene–drug relationships following a differential network analysis
- S Zickenrott
- , V E Angarica
- & A del Sol
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Original Article
| Open AccessPur-alpha functionally interacts with FUS carrying ALS-associated mutations
- M Di Salvio
- , V Piccinni
- & G Cestra
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Original Article
| Open AccessHaploinsufficiency of cathepsin D leads to lysosomal dysfunction and promotes cell-to-cell transmission of α-synuclein aggregates
- E-J Bae
- , N Y Yang
- & S-J Lee
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Original Article
| Open AccessIMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype
- S M Kessler
- , S Laggai
- & A K Kiemer
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Original Article
| Open AccessA novel lncRNA, LUADT1, promotes lung adenocarcinoma proliferation via the epigenetic suppression of p27
- M Qiu
- , Y Xu
- & L Xu
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Original Article
| Open AccessSeipin deficiency increases chromocenter fragmentation and disrupts acrosome formation leading to male infertility
- A E El Zowalaty
- , C Baumann
- & X Ye
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Review
| Open AccessMultiple sclerosis: getting personal with induced pluripotent stem cells
- A Di Ruscio
- , F Patti
- & G Amabile
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Original Article
| Open Accessp53 is active in murine stem cells and alters the transcriptome in a manner that is reminiscent of mutant p53
- H Yan
- , V Solozobova
- & C Blattner
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Original Article
| Open AccessIn a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification
- V Pendaries
- , M Le Lamer
- & M Simon
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Original Article
| Open AccessHDAC8 and STAT3 repress BMF gene activity in colon cancer cells
- Y Kang
- , H Nian
- & R H Dashwood
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Original Article
| Open AccessRestoration of miR-101 suppresses lung tumorigenesis through inhibition of DNMT3a-dependent DNA methylation
- F Yan
- , N Shen
- & S Liu
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Original Article
| Open AccessIntegrative epigenome analysis identifies a Polycomb-targeted differentiation program as a tumor-suppressor event epigenetically inactivated in colorectal cancer
- J Tan
- , X Yang
- & Q Yu
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Original Article
| Open AccessRnd3 haploinsufficient mice are predisposed to hemodynamic stress and develop apoptotic cardiomyopathy with heart failure
- X Yue
- , X Yang
- & J Chang
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Original Article
| Open AccessSenescence induced by RECQL4 dysfunction contributes to Rothmund–Thomson syndrome features in mice
- H Lu
- , E F Fang
- & V A Bohr
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Original Article
| Open AccessExpression of base excision repair key factors and miR17 in familial and sporadic breast cancer
- S De Summa
- , R Pinto
- & S Tommasi
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Original Article
| Open AccessLHX6 acts as a novel potential tumour suppressor with epigenetic inactivation in lung cancer
- W-b Liu
- , X Jiang
- & J-y Liu
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Original Article
| Open AccessCornelia de Lange Syndrome: NIPBL haploinsufficiency downregulates canonical Wnt pathway in zebrafish embryos and patients fibroblasts
- A Pistocchi
- , G Fazio
- & V Massa
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Correspondence
| Open AccessMammalian ncRNA-disease repository: a global view of ncRNA-mediated disease network
- Y Wang
- , L Chen
- & D Wang
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Original Article
| Open AccessHuman mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy
- J C Estrada
- , Y Torres
- & A Bernad
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Original Article
| Open AccessCPEB1, a histone-modified hypomethylated gene, is regulated by miR-101 and involved in cell senescence in glioma
- L Xiaoping
- , Y Zhibin
- & L Guiyuan
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Original Article
| Open AccessAutism spectrum disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1
- E Fujita
- , H Dai
- & T Momoi