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| Open AccessmiR-184 represses β-catenin and behaves as a skin tumor suppressor
- Lubov Turovsky
- , Ghazal Kheshaiboun
- & Emily Avitan-Hersh
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| Open AccessHMGA1 drives chemoresistance in esophageal squamous cell carcinoma by suppressing ferroptosis
- Jing-Yu Yang
- , Xin-Yuan Lei
- & Zhi-Xiang Xu
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| Open AccessThe regulations of telomerase reverse transcriptase (TERT) in cancer
- Mingdi Liu
- , Yuning Zhang
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| Open AccessCharacterization of BRCA2 R3052Q variant in mice supports its functional impact as a low-risk variant
- Arun Prakash Mishra
- , Suzanne Hartford
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| Open AccessThe roles of m6A methylation in cervical cancer: functions, molecular mechanisms, and clinical applications
- Zhonghao Mao
- , Bingyu Wang
- & Baoxia Cui
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| Open AccessA new vulnerability to BET inhibition due to enhanced autophagy in BRCA2 deficient pancreatic cancer
- EunJung Lee
- , Suyakarn Archasappawat
- & Chang-Il Hwang
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| Open AccessDeficiency of BAP1 inhibits neuroblastoma tumorigenesis through destabilization of MYCN
- Xiaoling Zhang
- , Xianling Cong
- & Xiangpeng Dai
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| Open AccessATAD2 is a driver and a therapeutic target in ovarian cancer that functions by upregulating CENPE
- Praveen Guruvaiah
- , Suresh Chava
- & Romi Gupta
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| Open AccessSuper-enhancer-driven MLX mediates redox balance maintenance via SLC7A11 in osteosarcoma
- Weitang Guo
- , Xin Wang
- & Changye Zou
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| Open AccessSMYD3 drives the proliferation in gastric cancer cells via reducing EMP1 expression in an H4K20me3-dependent manner
- Yi Zeng
- , Gang Ma
- & Yong Liu
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| Open AccessFBXO7, a tumor suppressor in endometrial carcinoma, suppresses INF2-associated mitochondrial division
- Hui Zhang
- , Yiting Zhao
- & Xiaofeng Jin
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Review Article
| Open AccessAberrant RNA m6A modification in gastrointestinal malignancies: versatile regulators of cancer hallmarks and novel therapeutic opportunities
- Li-Ting Shen
- , Lin-Rong Che
- & Bin Wang
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| Open AccessMETTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation
- Chengjie Lin
- , Ting Li
- & Shangeng Weng
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| Open AccessThe MYC-regulated lncRNA LNROP (ENSG00000254887) enables MYC-driven cell proliferation by controlling the expression of OCT2
- Daniel García-Caballero
- , Jonathan R. Hart
- & Peter K. Vogt
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| Open AccessA distal super-enhancer activates oncogenic ETS2 via recruiting MECOM in inflammatory bowel disease and colorectal cancer
- Yongheng Chen
- , Ying Ying
- & Xing-sheng Shu
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| Open AccessHsa_circ_0021727 (circ-CD44) promotes ESCC progression by targeting miR-23b-5p to activate the TAB1/NFκB pathway
- Fan Meng
- , Xiaokang Zhang
- & Xin He
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| Open AccessKDM6B promotes gastric carcinogenesis and metastasis via upregulation of CXCR4 expression
- Fen Liu
- , Yue Wang
- & Jihui Jia
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| Open AccessHigh-confidence cancer patient stratification through multiomics investigation of DNA repair disorders
- Garik V. Mkrtchyan
- , Alexander Veviorskiy
- & Morten Scheibye-Knudsen
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| Open AccessLncRNA SNHG1 regulates neuroblastoma cell fate via interactions with HDAC1/2
- Chia-Lang Hsu
- , Chieh-Fan Yin
- & Hsueh-Fen Juan
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| Open AccessACSL4-dependent ferroptosis does not represent a tumor-suppressive mechanism but ACSL4 rather promotes liver cancer progression
- Julia Grube
- , Marius Maximilian Woitok
- & Tobias Otto
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| Open AccessExosomal circWDR62 promotes temozolomide resistance and malignant progression through regulation of the miR-370-3p/MGMT axis in glioma
- Xiuchao Geng
- , Yuhao Zhang
- & Qiang Li
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| Open AccessHigh levels of NRF2 sensitize temozolomide-resistant glioblastoma cells to ferroptosis via ABCC1/MRP1 upregulation
- I. de Souza
- , L. K. S. Monteiro
- & C. R. R. Rocha
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| Open AccessSomatic FOXC1 insertion mutation remodels the immune microenvironment and promotes the progression of childhood acute lymphoblastic leukemia
- Yaping Wang
- , Xiaopeng Ma
- & Yongjun Fang
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Article
| Open AccessIntegrated DNA and RNA sequencing reveals early drivers involved in metastasis of gastric cancer
- Jieyun Zhang
- , Fatao Liu
- & Weijian Guo
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Article
| Open AccesscircFAM120B functions as a tumor suppressor in esophageal squamous cell carcinoma via the miR-661/PPM1L axis and the PKR/p38 MAPK/EMT pathway
- Huan Song
- , Dan Tian
- & Jianming Wang
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Article
| Open AccessGlobal characterization of extrachromosomal circular DNAs in advanced high grade serous ovarian cancer
- Yixuan Cen
- , Yifeng Fang
- & Junfen Xu
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Article
| Open AccessMESH1 knockdown triggers proliferation arrest through TAZ repression
- Tianai Sun
- , Chien-Kuang Cornelia Ding
- & Jen-Tsan Chi
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| Open AccessPCLAF promotes neuroblastoma G1/S cell cycle progression via the E2F1/PTTG1 axis
- Xiaowei Liu
- , Yuanxia Cai
- & Zhixiang Wu
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| Open AccessBlocking iASPP/Nrf2/M-CSF axis improves anti-cancer effect of chemotherapy-induced senescence by attenuating M2 polarization
- Hao Liu
- , Dong Zhao
- & Ying Hu
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| Open AccessStat4 rs7574865 polymorphism promotes the occurrence and progression of hepatocellular carcinoma via the Stat4/CYP2E1/FGL2 pathway
- Caie Wang
- , Na Gao
- & Hailing Qiao
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| Open AccessHBx increases chromatin accessibility and ETV4 expression to regulate dishevelled-2 and promote HCC progression
- Chuqian Zheng
- , Min Liu
- & Hong Fan
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| Open AccessDecreased PRC2 activity supports the survival of basal-like breast cancer cells to cytotoxic treatments
- Iga K. Mieczkowska
- , Garyfallia Pantelaiou-Prokaki
- & Florian Wegwitz
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| Open AccessSpatial transcriptomics reveals gene expression characteristics in invasive micropapillary carcinoma of the breast
- Jianke Lv
- , Qianqian Shi
- & Li Fu
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| Open AccessOverexpression of DTL enhances cell motility and promotes tumor metastasis in cervical adenocarcinoma by inducing RAC1-JNK-FOXO1 axis
- Sijia Liu
- , Lina Gu
- & Yan Jin
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| Open AccessNegative regulation of TGFβ-induced apoptosis by RAC1B enhances intestinal tumourigenesis
- Victoria Gudiño
- , Patrizia Cammareri
- & Kevin B. Myant
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| Open AccessA novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing
- Kajal Biswas
- , Martin Couillard
- & Shyam K. Sharan
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| Open AccessIdentification of a germline CSPG4 variation in a family with neurofibromatosis type 1-like phenotype
- Zhuanli Bai
- , Yiping Qu
- & Peng Hou
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| Open AccessSNP-mediated lncRNA-ENTPD3-AS1 upregulation suppresses renal cell carcinoma via miR-155/HIF-1α signaling
- Jiangyi Wang
- , Yun Zou
- & Zhong Wang
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| Open AccessPuma, noxa, p53, and p63 differentially mediate stress pathway induced apoptosis
- Jun Wang
- , Holly R. Thomas
- & John M. Parant
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Article
| Open AccessPredicting ROR1/BCL2 combination targeted therapy of small cell carcinoma of the lung
- Walter Z. Wang
- , Konstantin Shilo
- & David P. Carbone
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Article
| Open AccessAnti-miR-518d-5p overcomes liver tumor cell death resistance through mitochondrial activity
- Pablo Fernández-Tussy
- , Rubén Rodríguez-Agudo
- & María L. Martínez-Chantar
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| Open AccessSuppression of m6A mRNA modification by DNA hypermethylated ALKBH5 aggravates the oncological behavior of KRAS mutation/LKB1 loss lung cancer
- Donghong Zhang
- , Jinfeng Ning
- & Ming-Hui Zou
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Article
| Open AccessMCPIP1-mediated NFIC alternative splicing inhibits proliferation of triple-negative breast cancer via cyclin D1-Rb-E2F1 axis
- Fengxia Chen
- , Qingqing Wang
- & Yunfeng Zhou
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Article
| Open AccessNon-canonical role of wild-type SEC23B in the cellular stress response pathway
- Lamis Yehia
- , Darren Liu
- & Charis Eng
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Article
| Open AccessIdentification of a long non-coding RNA regulator of liver carcinoma cell survival
- Yulia Rybakova
- , John T. Gonzalez
- & Daniel G. Anderson
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Article
| Open AccessA distinct metabolic response characterizes sensitivity to EZH2 inhibition in multiple myeloma
- Patrick Nylund
- , Alba Atienza Párraga
- & Helena Jernberg-Wiklund
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Article
| Open AccessECT2 overexpression promotes the polarization of tumor-associated macrophages in hepatocellular carcinoma via the ECT2/PLK1/PTEN pathway
- Dafeng Xu
- , Yu Wang
- & Jinfang Zheng
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Review Article
| Open AccessUnveiling the ups and downs of miR-205 in physiology and cancer: transcriptional and post-transcriptional mechanisms
- Elena Ferrari
- & Paolo Gandellini
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Article
| Open AccessThe mechanism of m6A methyltransferase METTL3-mediated autophagy in reversing gefitinib resistance in NSCLC cells by β-elemene
- Shuiping Liu
- , Qiujie Li
- & Tian Xie