Genetics and Genomics
|
Open Access
Featured
-
-
Review
| Open AccessClinical utility of RASSF1A methylation in human malignancies
- A M Grawenda
- & E O'Neill
-
Molecular Diagnostics
| Open AccessmiR-9-3p plays a tumour-suppressor role by targeting TAZ (WWTR1) in hepatocellular carcinoma cells
- T Higashi
- , H Hayashi
- & H Baba
-
-
Epidemiology
| Open AccessFamily history of cancer and the risk of squamous cell carcinoma of oesophagus: a case–control study in Kashmir, India
- G A Bhat
- , I A Shah
- & N A Dar
-
Short Communication
| Open AccessPersonal history of rosacea and risk of incident cancer among women in the US
- W-Q Li
- , M Zhang
- & A A Qureshi
-
Genetics and Genomics
| Open AccessMC1R gene variants and non-melanoma skin cancer: a pooled-analysis from the M-SKIP project
- E Tagliabue
- , M C Fargnoli
- & S Raimondi
-
Translational Therapeutics
| Open AccessDual inhibition of survivin and MAOA synergistically impairs growth of PTEN-negative prostate cancer
- S Xu
- , H Adisetiyo
- & N Neamati
-
Molecular Diagnostics
| Open AccessThe expression of tumour suppressors and proto-oncogenes in tissues susceptible to their hereditary cancers
- Brian Muir
- & Leonard Nunney
-
Molecular Diagnostics
| Open AccessMicrosatellite instable vs stable colon carcinomas: analysis of tumour heterogeneity, inflammation and angiogenesis
- L De Smedt
- , J Lemahieu
- & X Sagaert
-
Epidemiology
| Open AccessAn analysis of the association between prostate cancer risk loci, PSA levels, disease aggressiveness and disease-specific mortality
- J Sullivan
- , R Kopp
- & R J Klein
-
Molecular Diagnostics
| Open AccessSNPs at miR-155 binding sites of TYRP1 explain discrepancy between mRNA and protein and refine TYRP1 prognostic value in melanoma
- P El Hajj
- , D Gilot
- & F Journe
-
Molecular Diagnostics
| Open AccessAssociation between cytosolic expression of BRCA1 and metastatic risk in breast cancer
- W L Santivasi
- , H Wang
- & Fen Xia
-
Molecular Diagnostics
| Open AccessExosomal microRNA in serum is a novel biomarker of recurrence in human colorectal cancer
- T Matsumura
- , K Sugimachi
- & K Mimori
-
Molecular Diagnostics
| Open AccessOncogenic CXCL10 signalling drives metastasis development and poor clinical outcome
- S C Wightman
- , A Uppal
- & N N Khodarev
-
Molecular Diagnostics
| Open AccessThe von Hippel–Lindau tumour suppressor gene: uncovering the expression of the pVHL172 isoform
- F Chesnel
- , P Hascoet
- & Y Arlot-Bonnemains
-
Molecular Diagnostics
| Open AccessMiR-320e is a novel prognostic biomarker in colorectal cancer
- L Perez-Carbonell
- , F A Sinicrope
- & A Goel
-
Molecular Diagnostics
| Open AccessAugmented expression of MYC and/or MYCN protein defines highly aggressive MYC-driven neuroblastoma: a Children’s Oncology Group study
- L L Wang
- , R Teshiba
- & H Shimada
-
Translational Therapeutics
| Open AccessMeta-analysis of BRAF mutation as a predictive biomarker of benefit from anti-EGFR monoclonal antibody therapy for RAS wild-type metastatic colorectal cancer
- A Rowland
- , M M Dias
- & M J Sorich
-
Clinical Study
| Open AccessPhase I study of FOLFIRI plus pimasertib as second-line treatment for KRAS-mutated metastatic colorectal cancer
- T Macarulla
- , A Cervantes
- & F Ciardiello
-
Genetics and Genomics
| Open AccessCombination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer
- T T Seppälä
- , J P Böhm
- & J-P Mecklin
-
Mini Review
| Open AccessNon-genetic cancer cell plasticity and therapy-induced stemness in tumour relapse: ‘What does not kill me strengthens me’
- A O Pisco
- & S Huang
-
Molecular Diagnostics
| Open AccessBRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection
- M Schirripa
- , F Bergamo
- & A Falcone
-
Translational Therapeutics
| Open AccessMicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms
- E B Amankwatia
- , P Chakravarty
- & G Smith
-
Full Paper
| Open AccessCirculating cell-free AR and CYP17A1 copy number variations may associate with outcome of metastatic castration-resistant prostate cancer patients treated with abiraterone
- S Salvi
- , V Casadio
- & U De Giorgi
-
Molecular Diagnostics
| Open AccessHPV-negative squamous cell carcinoma of the anal canal is unresponsive to standard treatment and frequently carries disruptive mutations in TP53
- D Meulendijks
- , N B Tomasoa
- & A Cats
-
Full Paper
| Open AccessFrequent MED12 mutations in phyllodes tumours of the breast
- M Yoshida
- , S Sekine
- & A Ochiai
-
Genetics and Genomics
| Open AccessActivating GNAS and KRAS mutations in gastric foveolar metaplasia, gastric heterotopia, and adenocarcinoma of the duodenum
- A Matsubara
- , R Ogawa
- & S Sekine
-
Molecular Diagnostics
| Open AccessCancer spectrum and frequency among children with Noonan, Costello, and cardio-facio-cutaneous syndromes
- C P Kratz
- , L Franke
- & M Zenker
-
Genetics and Genomics
| Open AccessTruncating mutations of PPM1D are found in blood DNA samples of lung cancer patients
- A Zajkowicz
- , D Butkiewicz
- & M Rusin
-
Clinical Study
| Open AccessCorrelation of extended RAS and PIK3CA gene mutation status with outcomes from the phase III AGITG MAX STUDY involving capecitabine alone or in combination with bevacizumab plus or minus mitomycin C in advanced colorectal cancer
- T J Price
- , M A Bruhn
- & N C Tebbutt
-
Genetics and Genomics
| Open AccessCirculating leukocyte telomere length and risk of overall and aggressive prostate cancer
- B Julin
- , I Shui
- & E A Platz
-
Mini Review
| Open AccessIt is not all about BRCA: Cullin-Ring ubiquitin Ligases in ovarian cancer
- A Carlucci
- & V D'Angiolella
-
Letter to the Editor
| Open AccessReply to ‘Comment on: The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysis’
- B Lajin
- & A Alachkar
-
Letter to the Editor
| Open AccessNeed for clarification of data in a recent meta-analysis on the association of NQO1 C609T polymorphism with cancer risk
- X Cao
- & W Shen
-
Mini Review
| Open AccessTranslation of genomics-guided RNA-based personalised cancer vaccines: towards the bedside
- V Boisguérin
- , J C Castle
- & U Sahin
-
Genetics and Genomics
| Open AccessB-RAF mutation and accumulated gene methylation in aberrant crypt foci (ACF), sessile serrated adenoma/polyp (SSA/P) and cancer in SSA/P
- A Inoue
- , K Okamoto
- & T Takayama
-
Genetics and Genomics
| Open AccessGenotranscriptomic meta-analysis of the Polycomb gene CBX2 in human cancers: initial evidence of an oncogenic role
- P-L Clermont
- , L Sun
- & C D Helgason
-
Molecular Diagnostics
| Open AccessKRAS mutational subtype and copy number predict in vitro response of human pancreatic cancer cell lines to MEK inhibition
- H Hamidi
- , M Lu
- & R S Finn
-
Genetics and Genomics
| Open AccessThe impact of a BRCA2 mutation on mortality from screen-detected prostate cancer
- M R Akbari
- , C J D Wallis
- & R K Nam
-
Molecular Diagnostics
| Open AccessLack of BAP1 protein expression in uveal melanoma is associated with increased metastatic risk and has utility in routine prognostic testing
- H Kalirai
- , A Dodson
- & S E Coupland
-
Clinical Study
| Open AccessBRCA1 mRNA levels following a 4–6-week intervention with oral 3,3′-diindolylmethane
- J Kotsopoulos
- , S Zhang
- & S A Narod
-
Genetics and Genomics
| Open AccessThe roles of HOXD10 in the development and progression of head and neck squamous cell carcinoma (HNSCC)
- F Hakami
- , L Darda
- & K D Hunter
-
Genetics and Genomics
| Open AccessKey Roles for MYC, KIT and RET signaling in secondary angiosarcomas
- E Styring
- , J Seinen
- & M Nilbert
-
Genetics and Genomics
| Open AccessBreast cancer risk after radiotherapy for heritable and non-heritable retinoblastoma: a US–UK study
- M P Little
- , M L Schaeffer
- & R A Kleinerman
-
Epidemiology
| Open AccessCoexistence of EGFR with KRAS, or BRAF, or PIK3CA somatic mutations in lung cancer: a comprehensive mutation profiling from 5125 Chinese cohorts
- S Li
- , L Li
- & N Liang
-
Letter to the Editor
| Open AccessComment on ‘The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysis’
- M A Malik
-
Letter to the Editor
| Open AccessReply: Comment on ‘The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysis’
- B Lajin
- & A Alachkar
-
Mini Review
| Open AccessPrevalence and implications of elevated microsatellite alterations at selected tetranucleotides in cancer
- M M C Watson
- , M Berg
- & K Søreide
-
Translational Therapeutics
| Open AccessRestoration of PPP2CA expression reverses epithelial-to-mesenchymal transition and suppresses prostate tumour growth and metastasis in an orthotopic mouse model
- A Bhardwaj
- , S Singh
- & A P Singh