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A recent retrospective study reporting increased risk of cardiovascular events and death with testosterone therapy has received extensive media attention. However, the authors' conclusions are highly questionable given the extensive data manipulation and serious methodological errors. Indeed, a rich body of literature strongly suggests that testosterone therapy offers cardiovascular benefits.
Urology nursing practice is rapidly developing around the world in response to technological advances, the expansion of service needs, and the increasing subspecialization of urology. Here, Helen Crowe provides unique insight into the successes and challenges of advanced urology nursing and the changing face of this specialty.
Illicit drug use can result in a wide spectrum of urological manifestations, which urologists should be able to recognize in their patients. Here, the authors summarize the known or reported urological complications of illicit drug use, providing relevant information on the pathophysiology and clinical presentation of these manifestations.
In this article, Nadal et al. review the pathological features, biology, clinical characteristics, and diagnostic challenges of SCC of the prostate, summarize the available treatment options, and highlight promising therapeutic strategies.
In this Review, Semins and Matlaga discuss risk factors for stone development during pregnancy and consider the diagnostic challenges that acute renal colic poses for pregnant patients. They also highlight potential stone-related complications for the mother and fetus, and specific management recommendations for this unique condition.
Despite increased use of robot-assisted radical prostatectomy (RARP), there is still a paucity of data defining the learning curve associated with this approach. A recent study suggests superior quality-of-life outcomes and improved surgical margin rates are achievable after a long learning curve for open surgeons who undertake RARP.
Intravesical BCG instillation is a longstanding therapy for bladder cancer, but its mode of action is still under investigation. This Review summarises the current understanding of the requirements for effective BCG therapy, and the putative roles of normal and malignant bladder cells, as well as the immune system, in the response to BCG.