Lara Crow

Epigenetics and epigenomics in diabetic kidney disease and metabolic memory

Latest Reviews

  • Review Article |

    Various cell types release extracellular DNA traps that protect the host against microbial infections. In this Review, the authors discuss how DNA traps not only participate in pathogen clearance but can also promote vascular disease and autoimmunity.

    • Christoph Daniel
    • , Moritz Leppkes
    • , Luis E. Muñoz
    • , Gunnar Schley
    • , Georg Schett
    •  & Martin Herrmann
  • Consensus Statement | | open

    This Evidence-Based Guideline developed by members of the European Society for Paediatric Nephrology CKD-MBD, Dialysis and Transplantation working groups presents clinical practice recommendations for the use of growth hormone in children with chronic kidney disease on dialysis and after renal transplantation.

    • Jens Drube
    • , Mandy Wan
    • , Marjolein Bonthuis
    • , Elke Wühl
    • , Justine Bacchetta
    • , Fernando Santos
    • , Ryszard Grenda
    • , Alberto Edefonti
    • , Jerome Harambat
    • , Rukshana Shroff
    • , Burkhard Tönshoff
    •  & Dieter Haffner
  • Review Article |

    This Review describes the mechanisms by which dietary, hormonal and metabolic factors regulate the expression and function of sodium-dependent phosphate cotransporters. The authors discuss the consequences of dysregulated phosphate transport and how understanding of the structure–function relationships of the transporters provides insights into their transport mechanisms.

    • Moshe Levi
    • , Enrico Gratton
    • , Ian C. Forster
    • , Nati Hernando
    • , Carsten A. Wagner
    • , Juerg Biber
    • , Victor Sorribas
    •  & Heini Murer
  • Review Article |

    In this Review, the authors discuss the biology of canonical and non-canonical inflammasomes and inflammasome-forming genes in the kidney, including their different functions in the various kidney compartments and their potential as therapeutic targets.

    • Takanori Komada
    •  & Daniel A. Muruve
  • Review Article |

    Here, the authors discuss the multiple functions of the (pro)renin receptor in physiological processes, including blood pressure regulation, energy metabolism and autophagy, as well as its roles in the pathogenesis of diseases including fibrosis, chronic kidney disease, pre-eclampsia and cancer.

    • Atsuhiro Ichihara
    •  & Midori Sasaki Yatabe
  • Consensus Statement | | open

    This Consensus Statement developed on behalf of the Network for Early Onset Cystic Kidney Disease provides guidance on counselling, diagnosing and monitoring children with autosomal dominant polycystic kidney disease based on current evidence and a multi-stakeholder discussion of ethical issues.

    • Charlotte Gimpel
    • , Carsten Bergmann
    • , Detlef Bockenhauer
    • , Luc Breysem
    • , Melissa A. Cadnapaphornchai
    • , Metin Cetiner
    • , Jan Dudley
    • , Francesco Emma
    • , Martin Konrad
    • , Tess Harris
    • , Peter C. Harris
    • , Jens König
    • , Max C. Liebau
    • , Matko Marlais
    • , Djalila Mekahli
    • , Alison M. Metcalfe
    • , Jun Oh
    • , Ronald D. Perrone
    • , Manish D. Sinha
    • , Andrea Titieni
    • , Roser Torra
    • , Stefanie Weber
    • , Paul J. D. Winyard
    •  & Franz Schaefer

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