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Motion is a key characteristic of every form of life. In this work, the authors use graphene drums to probe the nanomotion of a single bacterium and develop a new way for performing antibiotic susceptibility testing with single-cell resolution.
Deterministic single-photon sources are a key building block for photonic quantum technologies. Stimulated emission now helps tailoring spontaneous emission from a ladder-type three-level system in a single epitaxial quantum dot for bright polarized sources with a high photon purity and indistinguishability.
Cancer vaccines based on endogenous modified dendritic cells can activate cytotoxic T cells in an antigen-specific manner, but the short life of dendritic cells on injection in the body limits the efficacy of the strategies. Here the authors design biomimetic nanovesicles derived from antigen-presenting dendritic cell membranes for cancer vaccination and the simultaneous delivery of immune co-stimulatory molecules, showing robust antitumour activity in animal models.
This study provides insights into unifying mechanisms that explain the impact of engineered nanomaterials across species and identifies those that underlie differing sensitivities.
A two-dimensional transition metal dichalcogenide-on-compound-semiconductor fabrication method enables the realization of an active matrix micro-LED display.
A polyethersulfone–titanium dioxide membrane is demonstrated to be effective at micropollutant removal during the photocatalytic degradation of steroid hormones in a flow-through photocatalytic membrane reactor under UV light at environmentally relevant concentrations.
A low-cost plasmonic photocatalyst based on earth-abundant metals (Fe, Cu) maximizes solar energy conversion due to the concerted interplay of energies and interactions between reactants and hot carriers, thus producing aromatic amines with a high yield.
Current DNA computation techniques are slow in generating chemical outputs in response to chemical inputs and rely heavily on fluorescence readouts. Here, the authors introduce a new paradigm for DNA computation where the chemical input is processed and transduced into a mechanical output in the form of macroscopic locomotion using dynamic DNA-based motors.
Phase-change memtransistive synapses enable the implementation of biomimetic neural algorithms to perform tasks such as sequential learning and stochastic Hopfield computing networks.
Killing cells via rupturing their plasma membrane offers an attractive strategy to treat drug-resistant cancers, but it is currently highly toxic due to its low specificity. In this paper, the authors design a nanoscale detergent that can sense subtle pH variations and transforms into an active membranolytic agent at tumour acidity, remaining inactive in healthy tissues.
The implementation of parity–time symmetry in a complementary metal–oxide–semiconductor process technology enables the realization of wide-band high-quality microwave generation and broadband strong microwave isolation at gigahertz frequencies.
Vitreous opacities, which are collagen aggregates that form in the eye and cause vision impairment (eye floaters), are currently treated with invasive surgical intervention or high-energy laser photoablation. In this paper, the authors show that exposing gold nanoparticles or indocyanine green to low-energy laser pulses generates vapour nanobubbles that can disrupt collagen aggregates in the eyes of rabbit, suggesting a milder strategy for the treatment of eye floaters.
Nonlinear optical parametric polaritons are observed in a WS2 monolayer microcavity, opening the way for all-optical valley polariton nonlinear devices.
Chiral gold nanoparticles coated with enantiomerically pure phenylalanine were assembled into nanoporous membranes, whose ionic conductivity depends on the handedness of the incident circularly polarized light.
Majorana modes are highly non-local quantum states with non-Abelian exchange statistics, which localize at the two ends of finite-size 1D topological superconductors of sufficient length. By precisely positioning magnetic atoms on a superconducting surface, their interaction is tailored such that the precursors of Majorana modes are simultaneously observed on both ends of linear atomic chains.
A solvent-free and zero-waste method was reported for the synthesis of single-atom catalysts via abrading bulk metal into single atoms. This strategy works for different metals (iron, cobalt, nickel and copper or their alloys) and supports (carbons, oxides or nitrides).
A growth strategy based on surface-accumulated excess electrons enables the realization of non-oxidized bare copper nanoparticles stable under ambient conditions.
The extent to which mRNA delivery, as well as the cellular response to mRNA drug delivery vehicles, is conserved across species in vivo is unknown. Using species-independent DNA barcoding, the authors measure delivery in humanized, primatized and normal mice, and identify a potential mechanism driving species-dependent lipid nanoparticle delivery.
Graphene has a centrosymmetric crystal symmetry, which prohibits second-order effects in transport experiments. Yet, giant second-order nonlinear transports can emerge in graphene moiré superlattices at zero magnetic field, originating from the skew scattering of chiral Bloch electrons in the superlattice and giving rise to both longitudinal and transverse nonlinear conductivities under time-reversal symmetry.
