Handpicking extrachromosomal DNA

CRISPR catches extrachromosomal DNA

CRISPR-CATCH is a method that facilitates isolation of extrachromosomal DNA containing oncogenes from human cancer cells.


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  • The Qatar Genome Program was established to interrogate the genomics and genetics of populations in the Middle East. Improving precision medicine strategies and building long-term research capacity are both key aims of the initiative.

    • Hamdi Mbarek
    • Said I. Ismail
  • It has been 25 years since the release of GATTACA, a film that tells the story of a credible near future in which society’s inequalities, formerly associated with race and class, have been replaced with new prejudices based on genetic determinism. Here we compare GATTACA’s fictional technologies with reality’s state of the art, assessing the legal protections afforded in today’s society against GATTACA’s dystopian future in which personal freedom and privacy rights are substantially curtailed by genomic innovations. We further discuss how GATTACA’s prescient forewarnings are still relevant today in light of the current trajectory of genomic science and technology.

    • Dov Greenbaum
    • Mark Gerstein

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