Chromosome-level genome sequences of 69 diverse Arabidopsis thaliana strains reveal a quasi-fixed genome structure worldwide, in which large rearrangement is limited almost exclusively to the centromeric regions. Pan-genome analysis uncovered substantial diversity in gene content that, together with the genome assemblies, will fuel future genetic research.
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References
The Arabidopsis Genome Initiative. Analysis of the genome sequence of the flowering plant Arabidopsis thaliana. Nature 408, 796–815 (2000). This paper reports the first reference genome of A. thaliana.
Alonso-Blanco, C. et al. 1,135 genomes reveal the global pattern of polymorphism in Arabidopsis thaliana. Cell 166, 481–491 (2016). This paper reports the population structure and natural history of A. thaliana by genomic sequencing analysis of over 1,000 natural accessions.
Alonge, M. et al. Major impacts of widespread structural variation on gene expression and crop improvement in tomato. Cell 182, 145–161.e23 (2020). This paper reports the map of structural variants among 100 tomato genomes using long-read sequencing, and shows how multiple structural variants regulate fruit flavor, size and production.
Wlodzimierz, P. et al. Cycles of satellite and transposon evolution in Arabidopsis centromeres. Nature 618, 557–565 (2023). This paper reports the evolutionary dynamics of Arabidopsis centromeres from the genome assemblies of 66 accessions.
Kang, M. et al. The pan-genome and local adaptation of Arabidopsis thaliana. Nat. Commun. 14, 6259 (2023). This paper reports both a gene- and graph-based pan-genome of A. thaliana from the genome assemblies of 32 accessions, exploring the molecular mechanisms underlying the local adaptation.
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This is a summary of: Lian, Q. et al. A pan-genome of 69 Arabidopsis thaliana accessions reveals a conserved genome structure throughout the global species range. Nat. Genet. https://doi.org/10.1038/s41588-024-01715-9 (2024).
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Constants and variations in 69 diverse genomes of Arabidopsis thaliana. Nat Genet (2024). https://doi.org/10.1038/s41588-024-01716-8
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DOI: https://doi.org/10.1038/s41588-024-01716-8
