2022 tables: Institutions - life sciences - corporate

The 2022 tables are based on Nature Index data from 1 January 2021 to 31 December 2021.

Table criteria

# Institution Share 2020 Share 2021 Count 2021 Change in Adjusted Share 2020-2021*
1 F. Hoffmann-La Roche AG, Switzerland 42.88 35.34 111 -18.6%
2 Novartis International AG, Switzerland 18.42 17.88 82 -4.1%
3 AstraZeneca plc, United Kingdom (UK) 16.42 15.52 78 -6.6%
4 Pfizer Inc., United States of America (USA) 9.76 14.58 50 47.5%
5 Alphabet Inc., United States of America (USA) 11.88 13.28 40 10.5%
6 Regeneron Pharmaceuticals, Inc., United States of America (USA) 9.98 9.51 29 -5.8%
7 Amgen Inc., United States of America (USA) 10.01 9.40 36 -7.2%
8 BGI, China 7.34 8.83 47 19.0%
9 23andMe, Inc., United States of America (USA) 3.06 8.25 16 166.3%
10 Merck & Co., Inc., United States of America (USA) 7.26 7.39 28 0.6%
11 Johnson & Johnson, United States of America (USA) 8.47 6.40 38 -25.3%
12 Takeda Pharmaceutical Company Limited, Japan 2.16 6.12 18 180.2%
13 Vir Biotechnology, Inc., United States of America (USA) 3.11 6.09 17 93.4%
14 Leidos Holdings, Inc., United States of America (USA) 6.21 5.84 74 -7.1%
15 GlaxoSmithKline plc. (GSK), United Kingdom (UK) 11.69 5.80 38 -51.0%
16 New England Biolabs, Inc. (NEB), United States of America (USA) 1.31 5.53 10 318.0%
17 Sanofi, France 5.26 5.33 30 0.1%
18 Moderna, Inc., United States of America (USA) 2.86 4.60 13 59.2%
19 Gilead Sciences, Inc., United States of America (USA) 4.58 4.43 12 -4.5%
20 AbbVie Inc., United States of America (USA) 2.11 4.40 17 106.5%
21 Bristol-Myers Squibb (BMS), United States of America (USA) 3.63 4.28 20 16.6%
22 Biogen Inc., United States of America (USA) 3.39 4.26 18 24.4%
23 Formosa Plastics Group, Taiwan 6.00 4.25 19 -30.0%
24 Ionis Pharmaceuticals, Inc., United States of America (USA) 2.93 4.21 23 41.9%
25 Microsoft Corporation, United States of America (USA) 2.90 4.00 20 36.3%
26 Techint Group, Italy 3.22 3.79 25 16.2%
27 C. H. Boehringer Sohn AG & Co. KG (Boehringer Ingelheim), Germany 3.71 3.64 24 -2.8%
28 Eli Lilly and Company, United States of America (USA) 6.90 3.55 23 -49.1%
29 UCB S.A., Belgium 1.66 3.41 10 103.0%
30 BioNTech AG, Germany 2.77 3.07 11 9.8%
31 Eisai Co., Ltd., Japan 0.23 3.03 6 1,206.0%
32 Novo Nordisk A/S, Denmark 3.16 3.02 23 -5.4%
33 Bayer AG, Germany 3.83 2.84 17 -26.8%
34 Bioqual, Inc., United States of America (USA) 1.72 2.49 17 43.2%
35 Abbott Laboratories, United States of America (USA) 0.41 2.18 9 422.0%
36 IBM Corporation, United States of America (USA) 2.32 2.12 20 -9.8%
37 Thermo Fisher Scientific Inc., United States of America (USA) 3.17 2.10 16 -34.4%
38 China Shipbuilding Industry Corporation (CSIC), China 0.73 1.84 39 149.7%
39 10x Genomics, United States of America (USA) 1.06 1.81 11 69.5%
40 EpiCypher, Inc., United States of America (USA) 0.29 1.73 6 485.9%
41 PTC Therapeutics, United States of America (USA) 1.49 3 N/A
42 Mapp Biopharmaceutical, Inc., United States of America (USA) 0.63 1.49 7 134.8%
43 Merck KGaA, Germany 0.74 1.45 7 93.1%
44 NanoString Technologies, Inc., United States of America (USA) 1.73 1.44 8 -17.9%
45 DowDuPont Inc., United States of America (USA) 2.08 1.43 5 -32.1%
46 Sosei Co., Ltd., Japan 0.06 1.41 3 2,428.8%
47 BASF SE, Germany 0.31 1.40 6 341.1%
48 Lentigen Corporation, United States of America (USA) 0.33 1.38 2 309.0%
49 FiberHome Technologies Group, China 0.37 1.38 16 272.1%
50 Agios Pharmaceuticals, Inc., United States of America (USA) 0.61 1.36 4 120.5%

Footnote

Each year, the Nature Index publishes tables based on counts of high-quality research outputs in the previous calendar year. Users please note:

  1. The data behind the tables are based on a relatively small proportion of total research papers, they cover the natural sciences only and outputs are non-normalized (that is, they don’t reflect the size of the country or institution, or its overall research output).
  2. The Nature Index is one indicator of institutional research performance. The metrics of Count and Share used to order Nature Index listings are based on an institution’s or country’s publication output in 82 natural-science journals, selected on reputation by an independent panel of leading scientists in their fields.
  3. Nature Index recognizes that many other factors must be taken into account when considering research quality and institutional performance; Nature Index metrics alone should not be used to assess institutions or individuals.
  4. Nature Index data and methods are transparent and available under a creative commons licence at nature.com/nature-index/.

The Nature Index database undergoes regular updating, corrections, adjustment of institutional hierarchies, and removal of retracted papers and thus the live website can differ from the frozen annual tables.

*The change in adjusted Share accounts for the small annual variation in the total number of articles in Nature Index journals. Share values have been adjusted to 2021 levels to calculate the percentage change. For more information on the adjustment, please see the Adjusted metric explainer.