British Journal of Cancer

Series 19 April 2021

Molecular Diagnostics

The Molecular Diagnostics subject category is edited by Dr Lynette Sholl (Boston, USA). See below for the latest research from this subject category

Articles

Validation of tumour-free distance as novel prognostic marker in early-stage cervical cancer: a retrospective, single-centre, cohort study
- Nicolò Bizzarri
- Luigi Pedone Anchora
- Gabriella Ferrandina
Article14 Apr 2021 British Journal of Cancer
The circulating soluble form of the CD40 costimulatory immune checkpoint receptor and liver metastasis risk in rectal cancer
- Sebastian Meltzer
- Annette Torgunrud
- Anne Hansen Ree
ArticleOpen Access9 Apr 2021 British Journal of Cancer
Radiomics predicts risk of cachexia in advanced NSCLC patients treated with immune checkpoint inhibitors
- Wei Mu
- Evangelia Katsoulakis
- Robert J. Gillies
Article7 Apr 2021 British Journal of Cancer
Urinary oestrogen steroidome as an indicator of the risk of localised prostate cancer progression
- Jean-Philippe Emond
- Louis Lacombe
- Eric Lévesque
Article7 Apr 2021 British Journal of Cancer
Schlafen 11 predicts response to platinum-based chemotherapy in gastric cancers
- Tsuyoshi Takashima
- Daiki Taniyama
- Wataru Yasui
Article30 Mar 2021 British Journal of Cancer
Characterisation of circulating tumour cell phenotypes identifies a partial-EMT sub-population for clinical stratification of pancreatic cancer
- Alexander Semaan
- Vincent Bernard
- Paola A. Guerrero
Article30 Mar 2021 British Journal of Cancer
The prognostic value of combined measures of the systemic inflammatory response in patients with colon cancer: an analysis of 1700 patients
- Allan M. Golder
- Donald C. McMillan
- Campbell S. Roxburgh
Article24 Mar 2021 British Journal of Cancer
Retrospective observational study of HER2 immunohistochemistry in borderline breast cancer patients undergoing neoadjuvant therapy, with an emphasis on Group 2 (HER2/CEP17 ratio ≥2.0, HER2 copy number <4.0 signals/cell) cases
- Emad A. Rakha
- Islam M. Miligy
- Andrew H. S. Lee
ArticleOpen Access24 Mar 2021 British Journal of Cancer
Kinome-wide analysis of the effect of statins in colorectal cancer
- Sarah Ouahoud
- Rutger J. Jacobs
- James C. H. Hardwick
Article19 Mar 2021 British Journal of Cancer
Tertiary lymphoid structure score: a promising approach to refine the TNM staging in resected non-small cell lung cancer
- Mehrdad Rakaee
- Thomas K. Kilvaer
- Tom Donnem
Article15 Mar 2021 British Journal of Cancer
Transitions in oral and gut microbiome of HPV+ oropharyngeal squamous cell carcinoma following definitive chemoradiotherapy (ROMA LA-OPSCC study)
- Marc Oliva
- Pierre H. H. Schneeberger
- Anna Spreafico
ArticleOpen Access10 Mar 2021 British Journal of Cancer
Prognostic significance of interleukin-17A-producing colorectal tumour antigen-specific T cells
- Amanda Thomson
- Diana F. Costa Bento
- Andrew Godkin
ArticleOpen Access5 Mar 2021 British Journal of Cancer
Individual inflammatory marker abnormalities or inflammatory marker scores to identify primary care patients with unexpected weight loss for cancer investigation?
- B. D. Nicholson
- J. L. Oke
- F. D. R. Hobbs
ArticleOpen Access9 Feb 2021 British Journal of Cancer
Determination of breast cancer prognosis after neoadjuvant chemotherapy: comparison of Residual Cancer Burden (RCB) and Neo-Bioscore
- Enora Laas
- Julie Labrosse
- Fabien Reyal
ArticleOpen Access9 Feb 2021 British Journal of Cancer
Systemic inflammation scores correlate with survival prognosis in patients with newly diagnosed brain metastases
- Angelika M. Starzer
- Ariane Steindl
- Anna S. Berghoff
ArticleOpen Access21 Jan 2021 British Journal of Cancer
Discovery of a biomarker candidate for surgical stratification in high-grade serous ovarian cancer
- Haonan Lu
- Paula Cunnea
- Christina Fotopoulou
Article21 Jan 2021 British Journal of Cancer
Multi-protein spatial signatures in ductal carcinoma in situ (DCIS) of breast
- Sunil S. Badve
- Sanghee Cho
- Fiona Ginty
ArticleOpen Access7 Jan 2021 British Journal of Cancer
The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1⁺ tumour-infiltrating lymphocytes
- Diego Salas-Benito
- Enrique Conde
- Sandra Hervas-Stubbs
ArticleOpen Access5 Jan 2021 British Journal of Cancer
Biomarkers for site-specific response to neoadjuvant chemotherapy in epithelial ovarian cancer: relating MRI changes to tumour cell load and necrosis
- Jessica M. Winfield
- Jennifer C. Wakefield
- Nandita M. deSouza
ArticleOpen Access4 Jan 2021 British Journal of Cancer
SLFN11 informs on standard of care and novel treatments in a wide range of cancer models
- Claudia Winkler
- Joshua Armenia
- Elisabetta Leo
ArticleOpen Access18 Dec 2020 British Journal of Cancer
Tumour-free distance: a novel prognostic marker in patients with early-stage cervical cancer treated by primary surgery
- David Cibula
- Jiri Slama
- Roman Kocián
ArticleOpen Access14 Dec 2020 British Journal of Cancer
Fusobacterium nucleatum confers chemoresistance by modulating autophagy in oesophageal squamous cell carcinoma
- Yang Liu
- Yoshifumi Baba
- Hideo Baba
ArticleOpen Access10 Dec 2020 British Journal of Cancer
Development and validation of a novel staging system integrating the number and location of lymph nodes for gastric adenocarcinoma
- Ziyu Li
- Xiaolong Wu
- Jiafu Ji
ArticleOpen Access2 Dec 2020 British Journal of Cancer
Postoperative, but not preoperative, inflammation-based prognostic markers are prognostic factors in stage III colorectal cancer patients
- Kohei Yasui
- Dai Shida
- Yukihide Kanemitsu
ArticleOpen Access1 Dec 2020 British Journal of Cancer
Prognostic impact of peripheral blood neutrophil to lymphocyte ratio in advanced-stage pulmonary large cell neuroendocrine carcinoma and its association with the immune-related tumour microenvironment
- Masayuki Shirasawa
- Tatsuya Yoshida
- Noriko Motoi
ArticleOpen Access30 Nov 2020 British Journal of Cancer
The Glasgow Microenvironment Score associates with prognosis and adjuvant chemotherapy response in colorectal cancer
- Peter G. Alexander
- Antonia K. Roseweir
- James H. Park
ArticleOpen Access23 Nov 2020 British Journal of Cancer
The prognostic impact of RAS on overall survival following liver resection in early versus late-onset colorectal cancer patients
- Alexandre A. Jácome
- Timothy J. Vreeland
- Cathy Eng
ArticleOpen Access19 Nov 2020 British Journal of Cancer
Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site
- Maud Kamal
- Sonia Lameiras
- RAIDs Consortium
ArticleOpen Access16 Nov 2020 British Journal of Cancer
Prognostic significance of pre-treatment neutrophil-to-lymphocyte ratio (NLR) in patients with oropharyngeal cancer treated with radiotherapy
- Sweet Ping Ng
- Houda Bahig
- Adam S. Garden
ArticleOpen Access14 Oct 2020 British Journal of Cancer
G3BP1 interacts with YWHAZ to regulate chemoresistance and predict adjuvant chemotherapy benefit in gastric cancer
- Junjie Zhao
- Xuhong Fu
- Liyu Huang
ArticleOpen Access29 Sep 2020 British Journal of Cancer
Prognostic and predictive significance of nuclear HIF1α expression in locally advanced HNSCC patients treated with chemoradiation with or without nimotuzumab
- Usha Patel
- Manish Pandey
- Manoj B. Mahimkar
ArticleOpen Access17 Sep 2020 British Journal of Cancer
Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1
- Emarene Kalaw
- Malcolm Lim
- Amy E. McCart Reed
ArticleOpen Access17 Sep 2020 British Journal of Cancer
Novel urinary protein biomarker panel for early diagnosis of gastric cancer
- Takaya Shimura
- Delphine Dayde
- Hiromi Kataoka
ArticleOpen Access16 Sep 2020 British Journal of Cancer
Development of a non-invasive exhaled breath test for the diagnosis of head and neck cancer
- Nuwan Dharmawardana
- Thomas Goddard
- Roger Yazbeck
ArticleOpen Access9 Sep 2020 British Journal of Cancer
EGFR as a stable marker of prostate cancer dissemination to bones
- Paulina Nastały
- Sara Stoupiec
- Natalia Bednarz-Knoll
ArticleOpen Access9 Sep 2020 British Journal of Cancer
Real-world outcomes treating patients with advanced cutaneous squamous cell carcinoma with immune checkpoint inhibitors (CPI)
- Glenn J. Hanna
- Emily S. Ruiz
- Ann W. Silk
ArticleOpen Access1 Sep 2020 British Journal of Cancer
The nucleolar-related protein Dyskerin pseudouridine synthase 1 (DKC1) predicts poor prognosis in breast cancer
- Khloud A. Elsharawy
- Omar J. Mohammed
- Emad A. Rakha
ArticleOpen Access1 Sep 2020 British Journal of Cancer
Galectin-3 favours tumour metastasis via the activation of β-catenin signalling in hepatocellular carcinoma
- Mengjia Song
- Qiuzhong Pan
- Jian-Chuan Xia
ArticleOpen Access17 Aug 2020 British Journal of Cancer
Plasma-based early screening and monitoring of EGFR mutations in NSCLC patients by a 3-color digital PCR assay
- Xiang Song
- Jian Gong
- Li Chu
ArticleOpen Access12 Aug 2020 British Journal of Cancer
The clinical significance of oestrogen receptor expression in breast ductal carcinoma in situ
- Islam M. Miligy
- Michael S. Toss
- Emad A. Rakha
ArticleOpen Access10 Aug 2020 British Journal of Cancer
Central nervous system miliary metastasis in breast cancer: a case series analysis and proposed identification criteria of a rare metastasis subtype
- Sami I. Bashour
- Nuhad K. Ibrahim
- Gregory N. Fuller
ArticleOpen Access4 Aug 2020 British Journal of Cancer
Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models
- Charles R. Dunlop
- Yann Wallez
- Duncan I. Jodrell
ArticleOpen Access3 Aug 2020 British Journal of Cancer
Integrated clinico-molecular profiling of appendiceal adenocarcinoma reveals a unique grade-driven entity distinct from colorectal cancer
- Kanwal Raghav
- John P. Shen
- Cathy Eng
ArticleOpen Access31 Jul 2020 British Journal of Cancer
Prognostic value of nucleotyping, DNA ploidy and stroma in high-risk stage II colon cancer
- Lujing Yang
- Pengju Chen
- Aiwen Wu
ArticleOpen Access6 Jul 2020 British Journal of Cancer
Evaluation of p16^INK4a expression as a single marker to select patients with HPV-driven oropharyngeal cancers for treatment de-escalation
- Steffen Wagner
- Elena-Sophie Prigge
- Jens Peter Klussmann
ArticleOpen Access6 Jul 2020 British Journal of Cancer
Multicentre biomarker cohort study on the efficacy of nivolumab treatment for gastric cancer
- Takaomi Hagi
- Yukinori Kurokawa
- Yuichiro Doki
ArticleOpen Access3 Jul 2020 British Journal of Cancer
Syntenin-1 promotes colorectal cancer stem cell expansion and chemoresistance by regulating prostaglandin E2 receptor
- Kazuya Iwamoto
- Hidekazu Takahashi
- Hidetoshi Eguchi
ArticleOpen Access29 Jun 2020 British Journal of Cancer
Serial circulating tumour DNA analysis for locally advanced rectal cancer treated with preoperative therapy: prediction of pathological response and postoperative recurrence
- Satoshi Murahashi
- Takashi Akiyoshi
- Hitoshi Zembutsu
ArticleOpen Access22 Jun 2020 British Journal of Cancer
Clinical and pathological associations of PTEN expression in ovarian cancer: a multicentre study from the Ovarian Tumour Tissue Analysis Consortium
- Filipe Correia Martins
- Dominique-Laurent Couturier
- James D. Brenton
ArticleOpen Access18 Jun 2020 British Journal of Cancer
Oestrogen receptor pathway activity is associated with outcome in endometrial cancer
- Willem Jan van Weelden
- Louis J. M. van der Putten
- Johanna M. A. Pijnenborg
ArticleOpen Access8 Jun 2020 British Journal of Cancer
The relationships between systemic cytokine profiles and inflammatory markers in colorectal cancer and the prognostic significance of these parameters
- Ji Won Park
- Hee Jin Chang
- Jae Hwan Oh
ArticleOpen Access3 Jun 2020 British Journal of Cancer
A pre-specified model based on four kallikrein markers in blood improves predictions of adverse pathology and biochemical recurrence after radical prostatectomy
- Alexander Haese
- Amy L. Tin
- Guido Sauter
ArticleOpen Access29 May 2020 British Journal of Cancer
Prognostic significance of pre- and post-operative tumour markers for patients with gastric cancer
- Jun-Peng Lin
- Jian-Xian Lin
- Chang-Ming Huang
ArticleOpen Access26 May 2020 British Journal of Cancer
Defining COMMD4 as an anti-cancer therapeutic target and prognostic factor in non-small cell lung cancer
- Amila Suraweera
- Alex Duff
- Derek J. Richard
ArticleOpen Access22 May 2020 British Journal of Cancer
Identification of EMT-related high-risk stage II colorectal cancer and characterisation of metastasis-related genes
- Kai Wang
- Kai Song
- Wenyuan Zhao
ArticleOpen Access21 May 2020 British Journal of Cancer
The Pan-Immune-Inflammation Value is a new prognostic biomarker in metastatic colorectal cancer: results from a pooled-analysis of the Valentino and TRIBE first-line trials
- Giovanni Fucà
- Vincenzo Guarini
- Filippo Pietrantonio
ArticleOpen Access19 May 2020 British Journal of Cancer
Biomarker measurement in non-invasively sampled colorectal mucus as a novel approach to colorectal cancer detection: screening and triage implications
- Alexandre Loktionov
- Anet Soubieres
- Andrew Poullis
ArticleOpen Access13 May 2020 British Journal of Cancer
Lactate concentration in breast cancer using advanced magnetic resonance spectroscopy
- Sai Man Cheung
- Ehab Husain
- Jiabao He
ArticleOpen Access19 May 2020 British Journal of Cancer
11β hydroxysteroid dehydrogenase 1: a new marker for predicting response to immune-checkpoint blockade therapy in non-small-cell lung carcinoma
- Ryoko Saito
- Yasuhiro Miki
- Hironobu Sasano
ArticleOpen Access27 Apr 2020 British Journal of Cancer
Molecular profiling of stroma highlights stratifin as a novel biomarker of poor prognosis in pancreatic ductal adenocarcinoma
- Fabien Robin
- Gaëlle Angenard
- Laurent Sulpice
ArticleOpen Access7 May 2020 British Journal of Cancer
Early assessment of KRAS mutation in cfDNA correlates with risk of progression and death in advanced non-small-cell lung cancer
- Elisabetta Zulato
- Ilaria Attili
- Laura Bonanno
ArticleOpen Access7 May 2020 British Journal of Cancer
Nine-factor-based immunohistochemistry classifier predicts recurrence for early-stage hepatocellular carcinoma after curative resection
- Wei-Ren Liu
- Meng-Xin Tian
- Ying-Hong Shi
ArticleOpen Access7 May 2020 British Journal of Cancer
Combining measures of immune infiltration shows additive effect on survival prediction in high-grade serous ovarian carcinoma
- Anne Montfort
- Rowan J. Barker-Clarke
- James D. Brenton
ArticleOpen Access6 Apr 2020 British Journal of Cancer
Prognostic impact of ACTN4 gene copy number alteration in hormone receptor-positive, HER2-negative, node-negative invasive breast carcinoma
- Teppei Sugano
- Masayuki Yoshida
- Tesshi Yamada
ArticleOpen Access8 Apr 2020 British Journal of Cancer
Expression of RARRES1 and AGBL2 and progression of conventional renal cell carcinoma
- Lehel Peterfi
- Daniel Banyai
- Gyula Kovacs
ArticleOpen Access20 Apr 2020 British Journal of Cancer
Molecular subtypes of oropharyngeal cancer show distinct immune microenvironment related with immune checkpoint blockade response
- Min Hwan Kim
- Jae-Hwan Kim
- Hye Ryun Kim
ArticleOpen Access1 Apr 2020 British Journal of Cancer
The prognostic significance of immune microenvironment in breast ductal carcinoma in situ
- Michael S. Toss
- Asima Abidi
- Emad A. Rakha
ArticleOpen Access17 Mar 2020 British Journal of Cancer
OX40 and LAG3 are associated with better prognosis in advanced gastric cancer patients treated with anti-programmed death-1 antibody
- Hirofumi Ohmura
- Kyoko Yamaguchi
- Eishi Baba
ArticleOpen Access23 Mar 2020 British Journal of Cancer
Immune phenotype and histopathological growth pattern in patients with colorectal liver metastases
- Stefan Stremitzer
- Peter Vermeulen
- Stefan J. Scherer
ArticleOpen Access24 Mar 2020 British Journal of Cancer

Brief Communication

Detection of clustered circulating tumour cells in early breast cancer
- Ilona Krol
- Fabienne D. Schwab
- Nicola Aceto
Brief CommunicationOpen Access24 Mar 2021 British Journal of Cancer
Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer
- Shiqin Liu
- Michelle Shen
- Tanya Stoyanova
Brief CommunicationOpen Access8 Dec 2020 British Journal of Cancer
The significance of highlighting the oestrogen receptor low category in breast cancer
- Ivan K. Poon
- Julia Y. Tsang
- Gary M. Tse
Brief CommunicationOpen Access27 Jul 2020 British Journal of Cancer

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