●Focus on signalling The September 2002 issue of Nature Reviews Molecular Cell Biology is a focus issue on signalling. It is accompanied by a poster that is available free online throughout September 2002. It includes the following articles: STATs: transcriptional control and biological impact. Levy, D. E. & Darnell, J. E. Jr Mixed-lineage kinase control of JNK and p38 MAPK pathways. Gallo, K. A. & Johnson, G. L. γ-secretase-mediated proteolysis in cell-surface receptor signalling. Fortini, M. E.

●Braking WAVEs. Cory, G. O. C. & Ridley, A. J. Nature 15 August (2002) A News & Views article discussing recent work that investigated how WAVE1 is involved in the complex signalling pathways downstream of RAC that result in actin polymerization and cell motility.

Inflammation takes on Alzheimer disease. Golde, T. E. Nature Medicine September (2002) A News & Views article on the potential protective benefits of inflammation in Alzheimer disease.

●Why does remyelination fail in multiple sclerosis? Franklin, R. J. M. Nature Reviews Neuroscience September (2002)

●'Good' lipids for asthma. Peters-Golden, M. Nature Medicine September (2002) An eicosanoid lipid mediator might have diverse anti-asthmatic actions.

●Clinical proteomics: translating benchside promise into bedside reality. Petricoin, E. F., Zoon, K. C., Kohn, E. C., Barrett, J. C. & Liotta, L. A. Nature Reviews Drug Discovery September (2002)

●The Bcl-2 family: regulators of the cellular life-or-death switch. Cory, S. & Adams, J. Nature Reviews Cancer September (2002)

●Virus deals anthrax a killer blow. Rosovitz, M. J. & Leppla, S. H. Nature 22 August (2002)

●Life and death in effector T cells. Dooms, H. & Abbas, A. K. Nature Immunology September (2002) This News & Views article discusses new results that show that the development of a good memory response depends on the generation of T cells that do not produce much interferon, in direct contrast to what was believed previously.

●Transplantation — caught in the crossfire! Waldmann, H. Nature Immunology September (2002)