Review Article | 09 March 2020

Small molecule inhibitors targeting the PD-1/PD-L1 signaling pathway

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Volume 42 Issue 1

Review Article | 09 March 2020

Small molecule inhibitors targeting the PD-1/PD-L1 signaling pathway
- Qian Wu
- , Li Jiang
- , Si-cheng Li
- , Qiao-jun He
- , Bo Yang
- & Ji Cao
Review Article | 26 May 2020

Application of targeted therapy strategies with nanomedicine delivery for atherosclerosis
- Le-chun Ou
- , Shan Zhong
- , Jing-song Ou
- & Jin-wei Tian
Review Article | 06 March 2020

Research progress on the protective effects of licorice-derived 18β-glycyrrhetinic acid against liver injury
- Shou-yan Wu
- , Wen-jie Wang
- , Jin-hui Dou
- & Li-kun Gong
Review Article | 02 March 2020

The hepatotoxicity of Polygonum multiflorum: The emerging role of the immune-mediated liver injury
- Tai Rao
- , Ya-ting Liu
- , Xiang-chang Zeng
- , Chao-peng Li
- & Dong-sheng Ou-Yang
Article | 11 May 2020

An optically active isochroman-2H-chromene conjugate potently suppresses neuronal oxidative injuries associated with the PI3K/Akt and MAPK signaling pathways
- Ling-xue Tao
- , Sha-sha Ji
- , Dóra Szalóki
- , Tibor Kovács
- , Attila Mándi
- , Sándor Antus
- , Xun Ding
- , Tibor Kurtán
- & Hai-yan Zhang
Article | 25 May 2020

Drinking water temperature affects cognitive function and progression of Alzheimer’s disease in a mouse model
- Jiang-ping Wei
- , Wen Wen
- , Yuan Dai
- , Li-xia Qin
- , Yue-qiang Wen
- , Dayue Darrel Duan
- & Shi-jun Xu

Featured

Article | 26 May 2020

Gasdermin E-derived caspase-3 inhibitors effectively protect mice from acute hepatic failure
- Wan-feng Xu
- , Quan Zhang
- , Chu-jie Ding
- , Hui-yong Sun
- , Yuan Che
- , Hai Huang
- , Yun Wang
- , Jia-wei Wu
- , Hai-ping Hao
- & Li-juan Cao
Review Article | 02 December 2020

New therapeutics beyond amyloid-β and tau for the treatment of Alzheimer’s disease
- Feng Zhang
- , Ru-jia Zhong
- , Cheng Cheng
- , Song Li
- & Wei-dong Le
Article | 14 December 2020

EM-2 inhibited autophagy and promoted G₂/M phase arrest and apoptosis by activating the JNK pathway in hepatocellular carcinoma cells
- Jie Yang
- , Zhen-dong Li
- , Chang-yan Hou
- , Zi-yu Li
- , Qiang Li
- , Shen-yu Miao
- , Qing Zhang
- , Xiao-ying Zhang
- , Xiao-feng Zhu
- & Jian-wei Jiang

Acta Pharmacologica Sinica is a Transformative Journal; authors can publish using the traditional publishing route OR Open Access.
Our Open Access option complies with funder and institutional requirements.

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Article | 13 January 2021

A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis
- Yu-ting Liu
- , Hui-hua Ding
- , Ze-min Lin
- , Que Wang
- , Li Chen
- , Shuang-shuang Liu
- , Xiao-qian Yang
- , Feng-hua Zhu
- , Yue-teng Huang
- , Shi-qi Cao
- , Fang-ming Yang
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Brief Communication | 07 January 2021

Targeting DNA-PK overcomes acquired resistance to third-generation EGFR-TKI osimertinib in non-small-cell lung cancer
- Xing-mei Liang
- , Qiong Qin
- , Bo-ning Liu
- , Xiao-qing Li
- , Li-li Zeng
- , Jing Wang
- , Ling-ping Kong
- , Dian-sheng Zhong
- & Lin-lin Sun
Article | 07 January 2021

Vagal-α7nAChR signaling is required for lung anti-inflammatory responses and arginase 1 expression during an influenza infection
- Zhao-wei Gao
- , Ling Li
- , Yuan-yuan Huang
- , Cai-qi Zhao
- , Shuang-jia Xue
- , Jie Chen
- , Zhong-zhou Yang
- , Jin-fu Xu
- & Xiao Su
Article | 14 December 2020

EM-2 inhibited autophagy and promoted G₂/M phase arrest and apoptosis by activating the JNK pathway in hepatocellular carcinoma cells
- Jie Yang
- , Zhen-dong Li
- , Chang-yan Hou
- , Zi-yu Li
- , Qiang Li
- , Shen-yu Miao
- , Qing Zhang
- , Xiao-ying Zhang
- , Xiao-feng Zhu
- & Jian-wei Jiang
Article | 11 December 2020

Anti-PD-L1 mediating tumor-targeted codelivery of liposomal irinotecan/JQ1 for chemo-immunotherapy
- Zhi-di He
- , Meng Zhang
- , Yong-hui Wang
- , Yang He
- , Hai-rui Wang
- , Bin-fan Chen
- , Bin Tu
- , Si-qi Zhu
- & Yong-zhuo Huang

Focus

40 years of APS

04 September 2020

40 years of APS

We celebrate the 40th anniversary of Acta Pharmacologica Sinica (APS) with a series of specially commissioned Reviews and Articles across the diverse areas of the journal’s scope, highlighting the advances made in pharmacological research.

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Open Rank Tenure/Tenure Track Faculty Position, Molecular and Cellular Biophysics

University of North Carolina at Chapel Hill (UNC)
Postdoctoral Fellowship in Systems Biology and Drug Discovery

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