Vaccines

Definition

Vaccines are a clinical product that is composed of live or dead material from an infectious agent – bacterium, virus, fungus or parasite – that elicit protective immunity against the pathogen when administered. These substances are used to prevent the spread of infectious diseases.

Latest Research and Reviews

News and Comment

  • Comments and Opinion |

    Tracking who receives vaccines is essential, but will be impossible without innovations in digital technologies, says Seth Berkley.

    • Seth Berkley
    Nature 551, 273
  • News and Views |

    Dysfunctional immunity is associated with dengue hemorrhagic fever and dengue shock syndrome. Structural analyses reveal that a key germline-encoded contact between the T cell antigen receptor and a peptide underpins the immunodominance of dengue-virus-specific CD8+ T cell responses of weak affinity.

    • Sydney Blevins
    •  & Eric S Huseby
    Nature Immunology 18, 1186–1188
  • News and Views |

    Antimicrobial resistance in Neisseria gonorrhoeae compromises gonorrhoea treatment globally and vaccines might be the only sustainable solution for gonorrhoea control. A new study for the first time provides a proof of principle for protection with 31% effectiveness against gonorrhoea, owing to cross-protection by the outer membrane vesicle Neisseria meningitidis serogroup B vaccine (MeNZB).

    • Magnus Unemo
    •  & Aleksandra E. Sikora