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| Open AccessPhosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib
- Cristina Quintavalle
- , Sravanth Kumar Hindupur
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Original Article
| Open AccessCalreticulin promotes EGF-induced EMT in pancreatic cancer cells via Integrin/EGFR-ERK/MAPK signaling pathway
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| Open AccessPLOD2 regulated by transcription factor FOXA1 promotes metastasis in NSCLC
- Hongzhi Du
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| Open AccessRequirement for CCNB1 in mouse spermatogenesis
- Ji-Xin Tang
- , Jian Li
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Original Article
| Open AccessDemethylzeylasteral inhibits cell proliferation and induces apoptosis through suppressing MCL1 in melanoma cells
- Yuzu Zhao
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| Open AccessGadd45a opens up the promoter regions of miR-295 facilitating pluripotency induction
- Linpeng Li
- , Keshi Chen
- & Xingguo Liu
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Original Article
| Open AccessTenomodulin is essential for prevention of adipocyte accumulation and fibrovascular scar formation during early tendon healing
- Dasheng Lin
- , Paolo Alberton
- & Denitsa Docheva
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Original Article
| Open AccessImpairment of PTX3 expression in osteoblasts: a key element for osteoporosis
- Manuel Scimeca
- , Antonietta Salustri
- & Umberto Tarantino
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Original Article
| Open AccessMYCN contributes to the malignant characteristics of erythroleukemia through EZH2-mediated epigenetic repression of p21
- Li Liu
- , Feng Xu
- & Xiao Li
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Original Article
| Open AccessSecretory stressors induce intracellular death receptor accumulation to control apoptosis
- Bram J van Raam
- , Tamara Lacina
- & Jan H Reiling
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| Open AccessHSF4 regulates lens fiber cell differentiation by activating p53 and its downstream regulators
- Meng Gao
- , Yuwen Huang
- & Mugen Liu
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Original Article
| Open AccessEssential role of HCMV deubiquitinase in promoting oncogenesis by targeting anti-viral innate immune signaling pathways
- Puja Kumari
- , Irene Saha
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| Open AccessOveractive type 2 cannabinoid receptor induces meiosis in fetal gonads and impairs ovarian reserve
- Emanuela De Domenico
- , Federica Todaro
- & Paola Grimaldi
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Original Article
| Open AccessRegulation of RIP3 by the transcription factor Sp1 and the epigenetic regulator UHRF1 modulates cancer cell necroptosis
- Chengkui Yang
- , Jun Li
- & Sudan He
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Original Article
| Open AccessDisrupting CCT-β : β-tubulin selectively kills CCT-β overexpressed cancer cells through MAPKs activation
- Yan-Jin Liu
- , Vathan Kumar
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Original Article
| Open AccessNDRG1 inhibition sensitizes osteosarcoma cells to combretastatin A-4 through targeting autophagy
- Hongsheng Wang
- , Wen Li
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Original Article
| Open AccessLGR5 promotes cancer stem cell traits and chemoresistance in cervical cancer
- Hao-Zhe Cao
- , Xiao-Fang Liu
- & Peng-Sheng Zheng
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Original Article
| Open AccessAbcb1a and Abcb1b genes function differentially in blood–testis barrier dynamics in the rat
- Linlin Su
- , Yan C Cheng
- & Dahai Hu
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Original Article
| Open AccessThe functional relationship between transglutaminase 2 and transforming growth factor β1 in the regulation of angiogenesis and endothelial–mesenchymal transition
- Zhuo Wang
- , Mileidys Perez
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Original Article
| Open AccessRETRACTED ARTICLE: Matrine derivate MASM uncovers a novel function for ribosomal protein S5 in osteoclastogenesis and postmenopausal osteoporosis
- Xiao Chen
- , Xin Zhi
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Original Article
| Open Accessp73 is required for appropriate BMP-induced mesenchymal-to-epithelial transition during somatic cell reprogramming
- Marta Martin-Lopez
- , Laura Maeso-Alonso
- & Maria C Marin
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Original Article
| Open AccessTMEM74 promotes tumor cell survival by inducing autophagy via interactions with ATG16L1 and ATG9A
- Yizhe Sun
- , Yingyu Chen
- & Lu Wang
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Original Article
| Open AccessDual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells
- Yelyzaveta Shlyakhtina
- , Valeria Pavet
- & Hinrich Gronemeyer
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Original Article
| Open AccessMUC1 induces acquired chemoresistance by upregulating ABCB1 in EGFR-dependent manner
- Wei Jin
- , Xiaodong Liao
- & Lei Huang
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News and Commentary
| Open AccessYet another hump for CAML: support of cell survival independent of tail-anchored protein insertion
- Jennifer C Shing
- & Richard J Bram
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Original Article
| Open AccessThe cohesin complex prevents Myc-induced replication stress
- Sara Rohban
- , Aurora Cerutti
- & Stefano Campaner
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Original Article
| Open AccessMaml1 acts cooperatively with Gli proteins to regulate sonic hedgehog signaling pathway
- Roberta Quaranta
- , Maria Pelullo
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Original Article
| Open AccessHumanin G (HNG) protects age-related macular degeneration (AMD) transmitochondrial ARPE-19 cybrids from mitochondrial and cellular damage
- Sonali Nashine
- , Pinchas Cohen
- & M Cristina Kenney
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Original Article
| Open AccessInhibition of autophagy as a treatment strategy for p53 wild-type acute myeloid leukemia
- Hendrik Folkerts
- , Susan Hilgendorf
- & Edo Vellenga
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Original Article
| Open AccessMICU1 protects against myocardial ischemia/reperfusion injury and its control by the importer receptor Tom70
- Qiang Xue
- , Haifeng Pei
- & Ling Tao
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Original Article
| Open AccessUbiquitin-dependent regulation of Cdc42 by XIAP
- Arun Murali
- , Jaeyoung Shin
- & Krishnaraj Rajalingam
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Review
| Open AccessMYBL2 (B-Myb): a central regulator of cell proliferation, cell survival and differentiation involved in tumorigenesis
- Julian Musa
- , Marie-Ming Aynaud
- & Thomas GP Grünewald
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Correspondence
| Open AccessA hypoxia-inducible factor 1α null splice variant lacking exon 10
- Xiangyu Zhou
- , Weijia Zeng
- & Hongyan Wang
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Original Article
| Open AccessThe NF-κB1 is a key regulator of acute but not chronic renal injury
- Amy Fearn
- , Gerhard R Situmorang
- & Neil S Sheerin
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Original Article
| Open AccessEssential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart
- Lauren J Maskell
- , Kashif Qamar
- & Vishwanie S Budhram-Mahadeo
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Original Article
| Open AccessKnockdown of miR-128a induces Lin28a expression and reverts myeloid differentiation blockage in acute myeloid leukemia
- Luciana De Luca
- , Stefania Trino
- & Luigi Del Vecchio
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Original Article
| Open AccessDisease-linked connexin26 S17F promotes volar skin abnormalities and mild wound healing defects in mice
- Eric Press
- , Katanya C Alaga
- & Dale W Laird
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Original Article
| Open AccessBrg1-mediated Nrf2/HO-1 pathway activation alleviates hepatic ischemia–reperfusion injury
- Mian Ge
- , Weifeng Yao
- & Ziqing Hei
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Original Article
| Open AccessLoss of epidermal AP1 transcription factor function reduces filaggrin level, alters chemokine expression and produces an ichthyosis-related phenotype
- Christina A Young
- , Ellen A Rorke
- & Richard L Eckert
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Original Article
| Open AccessRegulator of G protein signaling 2 is a key regulator of pancreatic β-cell mass and function
- H Dong
- , Y Zhang
- & H Wang
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Review
| Open AccessThe role of extracellular histone in organ injury
- Eleanor Silk
- , Hailin Zhao
- & Daqing Ma
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Original Article
| Open AccessInhibition of SDF-1 receptors CXCR4 and CXCR7 attenuates acute pulmonary inflammation via the adenosine A2B-receptor on blood cells
- Franziska Magdalena Konrad
- , Nadine Meichssner
- & Jörg Reutershan
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Original Article
| Open AccessDeletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality
- Ge Li
- , Chentong Xu
- & Yingyu Chen
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Original Article
| Open AccessSurvivin, a key player in cancer progression, increases in obesity and protects adipose tissue stem cells from apoptosis
- Miriam Ejarque
- , Victòria Ceperuelo-Mallafré
- & Sonia Fernández-Veledo
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Original Article
| Open AccessTXNIP regulates mitophagy in retinal Müller cells under high-glucose conditions: implications for diabetic retinopathy
- Takhellambam Swornalata Devi
- , Mallika Somayajulu
- & Lalit Pukhrambam Singh
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Original Article
| Open Accessp45 NF-E2 regulates syncytiotrophoblast differentiation by post-translational GCM1 modifications in human intrauterine growth restriction
- Shrey Kohli
- , Juliane Hoffmann
- & Berend Isermann
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Original Article
| Open AccessC/EBPβ LIP augments cell death by inducing osteoglycin
- Rina Wassermann-Dozorets
- & Menachem Rubinstein
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News and Commentary
| Open AccessThe lure of the lipids: how defensins exploit membrane phospholipids to induce cytolysis in target cells
- Amy A Baxter
- , Ivan KH Poon
- & Mark D Hulett
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Original Article
| Open AccessForkhead box A3 attenuated the progression of fibrosis in a rat model of biliary atresia
- Rui Dong
- , Yifan Yang
- & Gong Chen
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