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| Open AccessELK3 destabilization by speckle-type POZ protein suppresses prostate cancer progression and docetaxel resistance
- Cheol-Jung Lee
- , Heejung Lee
- & Yong-Yeon Cho
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Article
| Open AccessNose-to-brain selective drug delivery to glioma via ferritin-based nanovectors reduces tumor growth and improves survival rate
- Francesco Marrocco
- , Elisabetta Falvo
- & Gianni Colotti
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Article
| Open AccessCasein kinase 2 phosphorylates and induces the SALL2 tumor suppressor degradation in colon cancer cells
- V. E. Hermosilla
- , L. Gyenis
- & R. Pincheira
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Article
| Open AccessPRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis
- Hao Liu
- , Xintian Chen
- & Xiangyang Yu
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Article
| Open AccessTNFSF15 inhibits progression of diabetic retinopathy by blocking pyroptosis via interacting with GSDME
- Hongkun Zhao
- , Yating Dai
- & Hua Li
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Review Article
| Open AccessThe implications of FASN in immune cell biology and related diseases
- Yucai Xiao
- , Yonghong Yang
- & Guanjun Dong
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Article
| Open AccessMDM2 provides TOP2 poison resistance by promoting proteolysis of TOP2βcc in a p53-independent manner
- Jianfeng Shu
- , Jinni Jiang
- & Ting Cai
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Article
| Open AccessUnexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control
- Daric J. Wible
- , Zalak Parikh
- & Shawn B. Bratton
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Article
| Open AccessLUBAC-mediated M1 Ub regulates necroptosis by segregating the cellular distribution of active MLKL
- Nadine Weinelt
- , Kaja Nicole Wächtershäuser
- & Sjoerd J. L. van Wijk
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Article
| Open AccessPalmitate induces integrated stress response and lipoapoptosis in trophoblasts
- Prakash Kumar Sahoo
- , Chandan Krishnamoorthy
- & Sathish Kumar Natarajan
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Article
| Open AccessUnveiling the mechanistic link between extracellular amyloid fibrils, mechano-signaling and YAP activation in cancer
- Francesco Farris
- , Alice Elhagh
- & Angela Bachi
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Article
| Open AccessAtypical cell death and insufficient matrix organization in long-bone growth plates from Tric-b-knockout mice
- Atsuhiko Ichimura
- , Yuu Miyazaki
- & Hiroshi Takeshima
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Article
| Open AccessElovanoid-N34 modulates TXNRD1 key in protection against oxidative stress-related diseases
- Jorgelina M. Calandria
- , Surjyadipta Bhattacharjee
- & Nicolas G. Bazan
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Article
| Open AccessCo-targeting HSP90 alpha and CDK7 overcomes resistance against HSP90 inhibitors in BCR-ABL1+ leukemia cells
- Melina Vogt
- , Niklas Dienstbier
- & Sanil Bhatia
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Article
| Open AccessMETTL3 promotes colorectal cancer progression through activating JAK1/STAT3 signaling pathway
- Yuechao Sun
- , Weipeng Gong
- & Song Zhang
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Article
| Open AccessDeciphering the interaction between Twist1 and PPARγ during adipocyte differentiation
- Leilei Sun
- , Shaoping Ji
- & Jian Yang
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Article
| Open AccessA novel c-Met/TRK inhibitor 1D228 efficiently inhibits tumor growth by targeting angiogenesis and tumor cell proliferation
- Baijiao An
- , Wenyan Nie
- & Geng Tian
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Article
| Open AccessGRSF1 antagonizes age-associated hypercoagulability via modulation of fibrinogen mRNA stability
- Doudou Liu
- , Chenzhong Xu
- & Jun Chen
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Article
| Open AccessThe identification of BCL-XL and MCL-1 as key anti-apoptotic proteins in medulloblastoma that mediate distinct roles in chemotherapy resistance
- Marie-Claire Fitzgerald
- , Philip J. O’Halloran
- & Brona M. Murphy
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Article
| Open AccessMacroH2A1.1 as a crossroad between epigenetics, inflammation and metabolism of mesenchymal stromal cells in myelodysplastic syndromes
- C. Giallongo
- , I. Dulcamare
- & G. A. Palumbo
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Article
| Open AccessDARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma
- Alexander Strubel
- , Philipp Münick
- & Volker Dötsch
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Article
| Open AccessInhibition of mitochondrial fission activates glycogen synthesis to support cell survival in colon cancer
- Sumati Hasani
- , Lyndsay E. A. Young
- & Tianyan Gao
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Article
| Open Accessα1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation
- Hao Wang
- , Xinyuan Cui
- & Qiu Yan
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Article
| Open AccessMRTF-A gain-of-function in mice impairs homeostatic renewal of the intestinal epithelium
- Anurag Kumar Singh
- , Amrita Rai
- & Guido Posern
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Article
| Open AccessIntracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells
- Flore Sneyers
- , Martijn Kerkhofs
- & Geert Bultynck
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Article
| Open AccessLZTR1 deficiency exerts high metastatic potential by enhancing sensitivity to EMT induction and controlling KLHL12-mediated collagen secretion
- Taiki Abe
- , Shin-ichiro Kanno
- & Yoko Aoki
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Article
| Open AccessThe deubiquitinase Leon/USP5 interacts with Atg1/ULK1 and antagonizes autophagy
- Yueh-Ling Pai
- , Yuchieh Jay Lin
- & Guang-Chao Chen
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Article
| Open AccessHeimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome
- Alice Capuz
- , Sylvain Osien
- & Michel Salzet
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Article
| Open AccessWWC1/2 regulate spinogenesis and cognition in mice by stabilizing AMOT
- Runyi Cao
- , Rui Zhu
- & Fa-Xing Yu
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Article
| Open AccessA transient increase of HIF-1α during the G1 phase (G1-HIF) ensures cell survival under nutritional stress
- Ratnal Belapurkar
- , Maximilian Pfisterer
- & M. Lienhard SCHMITZ
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Article
| Open AccessNitric oxide-induced ribosome collision activates ribosomal surveillance mechanisms
- Laura Ryder
- , Frederic Schrøder Arendrup
- & Simon Bekker-Jensen
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Article
| Open AccessFatty acid oxidation facilitates DNA double-strand break repair by promoting PARP1 acetylation
- Seungyeon Yang
- , Sunsook Hwang
- & Seung Min Jeong
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Article
| Open AccessLRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner
- Elżbieta Kania
- , Jaclyn S. Long
- & Jan B. Parys
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Editorial
| Open AccessCyclin-dependent kinases regulate the adult nervous system via the one-carbon-metabolism
- Alessia Angelin
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Article
| Open AccessA Dhdds K42E knock-in RP59 mouse model shows inner retina pathology and defective synaptic transmission
- Mai N. Nguyen
- , Dibyendu Chakraborty
- & Steven J. Pittler
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Article
| Open AccessIF1 ablation prevents ATP synthase oligomerization, enhances mitochondrial ATP turnover and promotes an adenosine-mediated pro-inflammatory phenotype
- Sonia Domínguez-Zorita
- , Inés Romero-Carramiñana
- & José M. Cuezva
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Article
| Open AccessTOPK promotes the growth of esophageal cancer in vitro and in vivo by enhancing YB1/eEF1A1 signal pathway
- Wenjie Wu
- , Jialuo Xu
- & Yanan Jiang
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Article
| Open AccessThe ufmylation modification of ribosomal protein L10 in the development of pancreatic adenocarcinoma
- Kun Wang
- , Siyu Chen
- & Yijun Chen
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Article
| Open AccessPerturbation of the host cell Ca2+ homeostasis and ER-mitochondria contact sites by the SARS-CoV-2 structural proteins E and M
- Elena Poggio
- , Francesca Vallese
- & Tito Calì
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Article
| Open AccessTRAP1 S-nitrosylation as a model of population-shift mechanism to study the effects of nitric oxide on redox-sensitive oncoproteins
- Elena Papaleo
- , Matteo Tiberti
- & Giuseppe Filomeni
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Article
| Open AccessDisease-related p63 DBD mutations impair DNA binding by distinct mechanisms and varying degree
- Christian Osterburg
- , Marco Ferniani
- & Volker Dötsch
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Article
| Open AccessPRPF19 facilitates colorectal cancer liver metastasis through activation of the Src-YAP1 pathway via K63-linked ubiquitination of MYL9
- Rui Zhou
- , Jie Chen
- & Lin Qiu
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Article
| Open AccessAstrocytes express aberrant immunoglobulins as putative gatekeeper of astrocytes to neuronal progenitor conversion
- Alice Capuz
- , Sylvain Osien
- & Michel Salzet
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Article
| Open AccessFBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2
- Rafael Jiménez-Izquierdo
- , Rosario Morrugares
- & Marco A. Calzado
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Article
| Open AccessThe phosphorylation of PHF5A by TrkA-ERK1/2-ABL1 cascade regulates centrosome separation
- Chen Song
- , Yu Zhang
- & Jianyuan Luo
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Review Article
| Open AccessTo be or not to be a fat burner, that is the question for cpt1c in cancer cells
- Rut Fadó
- , Sebastian Zagmutt
- & Núria Casals
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Article
| Open AccessThe mitochondrial inhibitor IF1 binds to the ATP synthase OSCP subunit and protects cancer cells from apoptosis
- Chiara Galber
- , Simone Fabbian
- & Valentina Giorgio
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Article
| Open AccessCrocetin antagonizes parthanatos in ischemic stroke via inhibiting NOX2 and preserving mitochondrial hexokinase-I
- Hao Wu
- , Ying Li
- & Dan Ohtan Wang
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Article
| Open AccessIncreased endogenous PKG I activity attenuates EGF-induced proliferation and migration of epithelial ovarian cancer via the MAPK/ERK pathway
- Ting Lan
- , Ying Li
- & Lan Luo
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