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| Open AccessDetermination of extended substrate specificity of the MALT1 as a strategy for the design of potent substrates and activity-based probes
- Paulina Kasperkiewicz
- , Sonia Kołt
- & Marcin Drąg
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| Open AccessTranexamic acid blocks the thrombin-mediated delay of epidermal permeability barrier recovery induced by the cedar pollen allergen, Cry j1
- S. Nakanishi
- , J. Kumamoto
- & M. Denda
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| Open AccessClpAP protease is a universal factor that activates the parDE toxin-antitoxin system from a broad host range RK2 plasmid
- Andrzej Dubiel
- , Katarzyna Wegrzyn
- & Igor Konieczny
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| Open AccessIncreased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptor
- Simone D. Scilabra
- , Martina Pigoni
- & Stefan F. Lichtenthaler
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| Open AccessIdentification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide–PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer
- Peng Lyu
- , Lilin Ge
- & Hang Fai Kwok
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| Open AccessUSP45 and Spindly are part of the same complex implicated in cell migration
- Claudia Conte
- , Eric R. Griffis
- & Ana B. Perez-Oliva
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| Open AccessA novel mechanism of plasminogen activation in epithelial and mesenchymal cells
- Moamen Bydoun
- , Andra Sterea
- & David M. Waisman
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| Open AccessSuper-silent FRET Sensor Enables Live Cell Imaging and Flow Cytometric Stratification of Intracellular Serine Protease Activity in Neutrophils
- Thomas H. Craven
- , Nicolaos Avlonitis
- & Kevin Dhaliwal
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| Open AccessPerrault syndrome type 3 caused by diverse molecular defects in CLPP
- Erica J. Brodie
- , Hanmiao Zhan
- & David A. Dougan
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| Open AccessA new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B
- D. Bosc
- , L. Vezenkov
- & R. N. Young
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| Open AccessEstrogen Action in the Epithelial Cells of the Mouse Vagina Regulates Neutrophil Infiltration and Vaginal Tissue Integrity
- Shuai Li
- , Gerardo G. Herrera
- & Wipawee Winuthayanon
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| Open AccessStructural determinants of specificity and regulation of activity in the allosteric loop network of human KLK8/neuropsin
- Mekdes Debela
- , Viktor Magdolen
- & Peter Goettig
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| Open AccessThe tomato subtilase family includes several cell death-related proteinases with caspase specificity
- Sven Reichardt
- , Dagmar Repper
- & Andreas Schaller
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| Open AccessInhibition of the precursor and mature forms of HIV-1 protease as a tool for drug evaluation
- Jana Humpolíčková
- , Jan Weber
- & Taťána Majerová
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| Open AccessDirect evidence of a low barrier hydrogen bond in the catalytic triad of a Serine protease
- Peter Agback
- & Tatiana Agback
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| Open AccessComparative proteomic analysis revealed complex responses to classical/novel duck reovirus infections in Cairna moschata
- Tao Yun
- , Jionggang Hua
- & Cun Zhang
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| Open AccessIdentification of serpins specific for activated protein C using a lysate-based screening assay
- Stéphanie G. I. Polderdijk
- & James A. Huntington
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| Open AccessThe mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes
- Ian Gaël Rodrigue-Gervais
- , Karine Doiron
- & Maya Saleh
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| Open AccessFunctional Proteomic Profiling of Secreted Serine Proteases in Health and Inflammatory Bowel Disease
- Alexandre Denadai-Souza
- , Chrystelle Bonnart
- & Céline Deraison
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| Open AccessThe Protease Activated Receptor2 Promotes Rab5a Mediated Generation of Pro-metastatic Microvesicles
- Kaushik Das
- , Ramesh Prasad
- & Prosenjit Sen
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| Open AccessHuman kallikrein-related peptidase 12 stimulates endothelial cell migration by remodeling the fibronectin matrix
- T. Kryza
- , C. Parent
- & N. Heuzé-Vourc’h
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| Open AccessFunctional cyclophilin D moderates platelet adhesion, but enhances the lytic resistance of fibrin
- Imre Varjú
- , Veronika Judit Farkas
- & Krasimir Kolev
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| Open AccessCementoin–SLPI fusion protein binds to human monocytes and epithelial cells and shows higher biological activity than SLPI
- Paulo C. Maffía
- , Diego Guerrieri
- & Eduardo Chuluyan
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| Open AccessComparative roles of clpA and clpB in the survival of S. Typhimurium under stress and virulence in poultry
- Lal Sangpuii
- , Sunil Kumar Dixit
- & Manish Mahawar
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| Open AccessStructural characterisation of the catalytic domain of botulinum neurotoxin X - high activity and unique substrate specificity
- Geoffrey Masuyer
- , Sicai Zhang
- & Pål Stenmark
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| Open AccessRare human Caspase-6-R65W and Caspase-6-G66R variants identify a novel regulatory region of Caspase-6 activity
- Agne Tubeleviciute-Aydin
- , Libin Zhou
- & Andrea C. LeBlanc
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| Open AccessRole of iRhom2 in intestinal ischemia-reperfusion-mediated acute lung injury
- Jee Hyun Kim
- , Jihye Kim
- & Joo Sung Kim
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| Open AccessOptimization of ClpXP activity and protein synthesis in an E. coli extract-based cell-free expression system
- Xinying Shi
- , Ti Wu
- & Simpson Joseph
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| Open AccessClove Bud Oil Modulates Pathogenicity Phenotypes of the Opportunistic Human Pathogen Pseudomonas aeruginosa
- Jayalekshmi Haripriyan
- , Athira Omanakuttan
- & Geetha B. Kumar
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| Open AccessSpecific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7
- Haolin Liu
- , Chao Wang
- & Gongyi Zhang
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| Open AccessHigh throughput protease profiling comprehensively defines active site specificity for thrombin and ADAMTS13
- Colin A. Kretz
- , Kärt Tomberg
- & David Ginsburg
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| Open AccessCrystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues
- Saori Roppongi
- , Yoshiyuki Suzuki
- & Takamasa Nonaka
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| Open AccessAPLP1 is endoproteolytically cleaved by γ-secretase without previous ectodomain shedding
- Linda Schauenburg
- , Filip Liebsch
- & Gerhard Multhaup
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| Open AccessIntermittent C1-Inhibitor Deficiency Associated with Recessive Inheritance: Functional and Structural Insight
- Sonia Caccia
- , Chiara Suffritti
- & Marco Cicardi
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| Open AccessInteraction of Complement Defence Collagens C1q and Mannose-Binding Lectin with BMP-1/Tolloid-like Proteinases
- Monique Lacroix
- , Agnès Tessier
- & Nicole M. Thielens
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| Open AccessThe serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover
- David J. Wilkinson
- , Antoine Desilets
- & Andrew D. Rowan
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| Open AccessConvergent evolution of plant and animal embryo defences by hyperstable non-digestible storage proteins
- María Yanina Pasquevich
- , Marcos Sebastián Dreon
- & Horacio Heras
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| Open AccessInsecticidal effects of dsRNA targeting the Diap1 gene in dipteran pests
- Michelle Powell
- , Prashant Pyati
- & Elaine Fitches
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| Open AccessProteolytic signatures define unique thrombin-derived peptides present in human wound fluid in vivo
- Rathi Saravanan
- , Sunil S. Adav
- & Artur Schmidtchen
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| Open AccessThe human blood parasite Schistosoma mansoni expresses extracellular tegumental calpains that cleave the blood clotting protein fibronectin
- Qiang Wang
- , Akram A. Da’dara
- & Patrick J. Skelly
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| Open AccessSelective Homogeneous Assay for Circulating Endopeptidase Fibroblast Activation Protein (FAP)
- Travis W. Bainbridge
- , Diana Ronai Dunshee
- & James A. Ernst
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| Open AccessIdentification and characterization of the novel reversible and selective cathepsin X inhibitors
- Urša Pečar Fonović
- , Ana Mitrović
- & Janko Kos
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| Open AccessHalotolerant aminopeptidase M29 from Mesorhizobium SEMIA 3007 with biotechnological potential and its impact on biofilm synthesis
- Elwi Machado Sierra
- , Mariana Rangel Pereira
- & Eliana G. de Macedo Lemos
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| Open AccessGlaucoma is associated with plasmin proteolytic activation mediated through oxidative inactivation of neuroserpin
- Vivek Gupta
- , Mehdi Mirzaei
- & Stuart Graham
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| Open AccessQuantitative proteomics screen identifies a substrate repertoire of rhomboid protease RHBDL2 in human cells and implicates it in epithelial homeostasis
- Nicholas Johnson
- , Jana Březinová
- & Kvido Strisovsky
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| Open AccessMass spectrometry-based determination of Kallikrein-related peptidase 7 (KLK7) cleavage preferences and subsite dependency
- Lakmali Munasinghage Silva
- , Thomas Stoll
- & Judith Ann Clements
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| Open AccessKnowledge-transfer learning for prediction of matrix metalloprotease substrate-cleavage sites
- Yanan Wang
- , Jiangning Song
- & Hong-Bin Shen
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| Open AccessPlasticity in the Oxidative Folding Pathway of the High Affinity Nerita Versicolor Carboxypeptidase Inhibitor (NvCI)
- Sebastián A. Esperante
- , Giovanni Covaleda
- & Salvador Ventura