Proteases are enzymes that catalyse hydrolysis of the peptide and isopeptide bonds that join amino acids within proteins (known as proteolysis). Proteases can also remove protein post-translational modifications. Exopeptidases remove the terminal amino acids from the protein chain and endopeptidases attack an internal peptide bond, as in trypsin, chymotrypsin, pepsin, elastase and papain.
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News and Views |Nature Structural and Molecular Biology 24, 337–339
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