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| Open AccessAgonist-selective activation of individual G-proteins by muscarinic receptors
- Dominik Nelic
- , Nikolai Chetverikov
- & Alena Janoušková-Randáková
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Article
| Open AccessMetabolic engineering of omega-3 long chain polyunsaturated fatty acids in plants using different ∆6- and ∆5-desaturases co-expressed with LPCAT from the marine diatom Phaeodactylum tricornutum
- Sylwia Klińska-Bąchor
- , Kamil Demski
- & Antoni Banaś
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Article
| Open AccessUrinary metabolomic profiling of a cohort of Colombian patients with systemic lupus erythematosus
- Alejandra Rojo-Sánchez
- , Ada Carmona-Martes
- & Lisandro A. Pacheco-Lugo
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Article
| Open AccessDesign, synthesis, and evaluation of novel arecoline-linked amino acid derivatives for insecticidal and antifungal activities
- Chaohai Pang
- , Yuan Xu
- & Bingjun Han
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Article
| Open AccessTackling new psychoactive substances through metabolomics: UHPLC-HRMS study on natural and synthetic opioids in male and female murine models
- Gaia Di Francesco
- , Camilla Montesano
- & Manuel Sergi
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Article
| Open AccessRibosomal S6 kinase 2-forkhead box protein O4 signaling pathway plays an essential role in melanogenesis
- Dohyun Jeung
- , Ga-Eun Lee
- & Yong-Yeon Cho
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Article
| Open AccessSkeletal muscle differentiation induces wide-ranging nucleosome repositioning in muscle gene promoters
- Sonalí Harris
- , Iqra Anwar
- & Conrad P. Hodgkinson
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Article
| Open AccessExploring a repurposed candidate with dual hIDO1/hTDO2 inhibitory potential for anticancer efficacy identified through pharmacophore-based virtual screening and in vitro evaluation
- Nourhan M. Aboomar
- , Omar Essam
- & Reem K. Arafa
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Article
| Open AccessPredicting FFAR4 agonists using structure-based machine learning approach based on molecular fingerprints
- Zaid Anis Sherwani
- , Syeda Sumayya Tariq
- & Zaheer Ul-Haq
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Article
| Open AccessPotential therapeutic targets for COVID-19 complicated with pulmonary hypertension: a bioinformatics and early validation study
- Qingbin Hou
- , Jinping Jiang
- & Yaling Han
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Article
| Open AccessCatalytic specificity and crystal structure of cystathionine γ-lyase from Pseudomonas aeruginosa
- Marco Pedretti
- , Carmen Fernández-Rodríguez
- & Luis Alfonso Martínez-Cruz
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Article
| Open AccessSpectroscopic insight into breast cancer: profiling small extracellular vesicles lipids via infrared spectroscopy for diagnostic precision
- Abhay Mishra
- , Sadaqa Zehra
- & Saroj Kumar
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Article
| Open AccessRAPID resistance to BET inhibitors is mediated by FGFR1 in glioblastoma
- Anna M. Jermakowicz
- , Alison M. Kurimchak
- & Nagi G. Ayad
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Article
| Open AccessInvestigation of thrombin concentration at the time of clot formation in simultaneous thrombin and fibrin generation assays
- Ivan D. Tarandovskiy
- , Stepan S. Surov
- & Mikhail V. Ovanesov
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Article
| Open AccessDiscovery of gefitinib-1,2,3-triazole derivatives against lung cancer via inducing apoptosis and inhibiting the colony formation
- En Gao
- , Ya Wang
- & Shouhu Li
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Article
| Open AccessMitochondrial enzyme FAHD1 reduces ROS in osteosarcoma
- Anne Heberle
- , Elia Cappuccio
- & Alexander K. H. Weiss
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Article
| Open AccessHexahydrocannabinol (HHC) and Δ9-tetrahydrocannabinol (Δ9-THC) driven activation of cannabinoid receptor 1 results in biased intracellular signaling
- Oleh Durydivka
- , Petr Palivec
- & Martin Kuchar
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Article
| Open AccessDifferences in physicochemical properties of pectin extracted from pomelo peel with different extraction techniques
- Yangyang Yu
- , Ping Lu
- & Hongli Chen
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Article
| Open AccessOptimization of plasma-based BioID identifies plasminogen as a ligand of ADAMTS13
- Hasam Madarati
- , Veronica DeYoung
- & Colin A. Kretz
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Article
| Open AccessApigetrin ameliorates doxorubicin prompted testicular damage: biochemical, spermatological and histological based study
- Muhammad Umar Ijaz
- , Saba Yaqoob
- & Suhail Razak
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Article
| Open AccessSynthesis, biofilm formation inhibitory, and inflammation inhibitory activities of new coumarin derivatives
- Ghada E. Ahmed
- , Zeinab A. Elshahid
- & Anhar Abdel-Aziem
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Article
| Open AccessSynthesis, structural, molecular docking, and in vitro biological activities of Cu-doped ZnO nanomaterials
- Ahmed F. El-Sayed
- , Wael M. Aboulthana
- & Sahar M. Mousa
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Article
| Open AccessType 1 secretion necessitates a tight interplay between all domains of the ABC transporter
- Manuel T. Anlauf
- , Florestan L. Bilsing
- & Lutz Schmitt
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Article
| Open AccessAnalysis of plasma metabolomes from 11 309 subjects in five population-based cohorts
- Nilanjana Ghosh
- , Carl Lejonberg
- & J. Gustav Smith
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Article
| Open AccessSoluble programmed death ligand 1 as prognostic biomarker in non-small cell lung cancer patients receiving nivolumab, pembrolizumab or atezolizumab therapy
- Sinne Søberg Brun
- , Torben Frøstrup Hansen
- & Line Nederby
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Article
| Open AccessXbra modulates the activity of linker region phosphorylated Smad1 during Xenopus development
- Santosh Kumar
- , Zobia Umair
- & Jaebong Kim
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Article
| Open AccessUnravelling the effect of droplet size on lipid oxidation in O/W emulsions by using microfluidics
- Sten ten Klooster
- , Vincent J. P. Boerkamp
- & Claire C. Berton-Carabin
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Article
| Open AccessMolecular detection of exosomal miRNAs of blood serum for prognosis of colorectal cancer
- Tahani Bakhsh
- , Safiah Alhazmi
- & Ahmed Bahieldin
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Article
| Open AccessAn aberrant fused in sarcoma liquid droplet of amyotrophic lateral sclerosis pathological variant, R495X, accelerates liquid–solid phase transition
- Yutaro Shiramasa
- , Ryu Yamamoto
- & Ryo Kitahara
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Article
| Open AccessTheoretical and mathematical codynamics of nonlinear tuberculosis and COVID-19 model pertaining to fractional calculus and probabilistic approach
- Saima Rashid
- , Sher Zaman Hamidi
- & Beida Mohsen Tami Alsubei
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Article
| Open AccessThe role of the correlated motion(s) of the chromophore in photoswitching of green and red forms of the photoconvertible fluorescent protein mSAASoti
- Alexandra V. Gavshina
- , Ilya D. Solovyev
- & Alexander P. Savitsky
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Article
| Open AccessOptimization of culture medium to improve bio-cementation effect based on response surface method
- Zhikun Pan
- & Shiding Cao
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Article
| Open AccessCombination of losartan with pirfenidone: a protective anti-fibrotic against pulmonary fibrosis induced by bleomycin in rats
- Arian Amirkhosravi
- , Maryamossadat Mirtajaddini Goki
- & Mehrnaz Mehrabani
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Article
| Open AccessThe effect of a rotating magnetic field on the antioxidant system in healthy volunteers - preliminary study
- Elżbieta Cecerska-Heryć
- , Marta Gliźniewicz
- & Barbara Dołęgowska
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Article
| Open AccessImpact of floral and geographical origins on honey quality parameters in Saudi Arabian regions
- Wed Mohammed Ali Alaerjani
- & Mohammed Elimam Ahamed Mohammed
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Article
| Open AccessRadiolysis of myoglobin concentrated gels by protons: specific changes in secondary structure and production of carbon monoxide
- Nicolas Ludwig
- , Catherine Galindo
- & Quentin Raffy
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Article
| Open AccessMolecular modelling studies and in vitro enzymatic assays identified A 4-(nitrobenzyl)guanidine derivative as inhibitor of SARS-CoV-2 Mpro
- Kaio Maciel de Santiago-Silva
- , Priscila Goes Camargo
- & Marcelle de Lima Ferreira Bispo
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Article
| Open AccessQuantitative measurement of internal quality of carrots using hyperspectral imaging and multivariate analysis
- Arcel Mutombo Mulowayi
- , Zhen Hui Shen
- & Shu He Zheng
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Article
| Open AccessDual pH/redox-responsive hyperbranched polymeric nanocarriers with TME-trigger size shrinkage and charge reversible ability for amplified chemotherapy of breast cancer
- Fahimeh Badparvar
- , Ahmad Poursattar Marjani
- & Fatemeh Ramezani
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Article
| Open AccessMolecular identification of Proteus mirabilis, Vibrio species leading to CRISPR-Cas9 modification of tcpA and UreC genes causing cholera and UTI
- Muhammad Naveed
- , Fatima Tahir
- & Abdullah F. Alasmari
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Article
| Open AccessPossible involvement of zinc transporter ZIP13 in myogenic differentiation
- Masaki Shoji
- , Takuto Ohashi
- & Takashi Kuzuhara
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Article
| Open AccessPredictors of severe hepatotoxicity among retroviral infected adults on HAART regimen in Ilubabor Zone, Southwest Ethiopia
- Tefera Darge
- , Alemayehu Babusha
- & Sisay Teferi
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Article
| Open AccessComparative transcriptome analysis of longissimus dorsi muscle reveal potential genes affecting meat trait in Chinese indigenous Xiang pig
- Wei Wang
- , Dan Wang
- & Jiafu Wang
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Article
| Open AccessHypoxia enhances autophagy level of human sperms
- Jie Hu
- , Jiwei Wu
- & Yonghua He
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Article
| Open AccessExpression and processing of mature human frataxin after gene therapy in mice
- Teerapat Rojsajjakul
- , Nithya Selvan
- & Ian A. Blair
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Article
| Open AccessHypoxia treatment and resistance training alters microRNA profiling in rats skeletal muscle
- Tao Mei
- , Yang Hu
- & Yanchun Li
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Article
| Open AccessBreak oily water emulsion during petroleum enhancing production processes using green approach for the synthesis of SnCuO@FeO nanocomposite from microorganisms
- M. Hosny
- , Mahmoud F. Mubarak
- & R. Hosny
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Article
| Open AccessMechanism of antagonist ligand binding to REV-ERBα
- Mohammad Homaidur Rahman
- & Lamees Hegazy
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Article
| Open AccessPredicted genetic burden and frequency of phenotype-associated variants in the horse
- S. A. Durward-Akhurst
- , J. L. Marlowe
- & M. E. McCue
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