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Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation
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Development of a sandwich ELISA to detect circulating, soluble IRAP as a potential disease biomarker
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Serine proteases and metalloproteases are highly increased in irritable bowel syndrome Tunisian patients
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Structure–function analysis of histone H2B and PCNA ubiquitination dynamics using deubiquitinase-deficient strains
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Production and properties of adhesin-free gingipain proteinase RgpA
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Proteomic analysis of the effect of hemin in breast cancer
- G. P. Coló
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Ebselen derivatives inhibit SARS-CoV-2 replication by inhibition of its essential proteins: PLpro and Mpro proteases, and nsp14 guanine N7-methyltransferase
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Utilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14
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Spiders’ digestive system as a source of trypsin inhibitors: functional activity of a member of atracotoxin structural family
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Brewers’ spent hop revalorization for the production of high added-value cosmetics ingredients with elastase inhibition capacity
- Maria Paredes-Ramos
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Live imaging of apoptotic signaling flow using tunable combinatorial FRET-based bioprobes for cell population analysis of caspase cascades
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Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage
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Promising SARS-CoV-2 main protease inhibitor ligand-binding modes evaluated using LB-PaCS-MD/FMO
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Directed evolution for soluble and active periplasmic expression of bovine enterokinase in Escherichia coli
- Weiluo Lee
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Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel
- Rikke Zachar
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Evaluation of the anti-SARS-CoV-2 properties of essential oils and aromatic extracts
- Daniel Jan Strub
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Reengineering the specificity of the highly selective Clostridium botulinum protease via directed evolution
- Rebekah P. Dyer
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Exogenous human α-Synuclein acts in vitro as a mild platelet antiaggregant inhibiting α-thrombin-induced platelet activation
- Laura Acquasaliente
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Exploring selective autophagy events in multiple biologic models using LC3-interacting regions (LIR)-based molecular traps
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Characterization and molecular docking study of cathepsin L inhibitory peptides (SnuCalCpIs) from Calotropis procera R. Br
- Chang Woo Kwon
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A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa
- Anders B. Sorensen
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Effects of intracellular calcium accumulation on proteins encoded by the major genes underlying amyotrophic lateral sclerosis
- Giovanni De Marco
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Inflammatory activation of surface molecule shedding by upregulation of the pseudoprotease iRhom2 in colon epithelial cells
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Deep mutational scanning of the plasminogen activator inhibitor-1 functional landscape
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Embryotoxic activity of 3C protease of human hepatitis A virus in developing Danio rerio embryos
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The gene repertoire of the main cysteine protease of Trypanosoma cruzi, cruzipain, reveals four sub-types with distinct active sites
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RAS specific protease induces irreversible growth arrest via p27 in several KRAS mutant colorectal cancer cell lines
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The ERAP1 active site cannot productively access the N-terminus of antigenic peptide precursors stably bound onto MHC class I
- George Mavridis
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A KLK4 proteinase substrate capture approach to antagonize PAR1
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Role of cholesterol in substrate recognition by \(\gamma\)-secretase
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Serine proteases profiles of Leishmania (Viannia) braziliensis clinical isolates with distinct susceptibilities to antimony
- Anabel Zabala-Peñafiel
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Peptide profiling in cow urine reveals molecular signature of physiology-driven pathways and in-silico predicted bioactive properties
- Rohit Kumar
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A conserved rhizobial peptidase that interacts with host-derived symbiotic peptides
- Alex B. Benedict
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Structural basis for an exceptionally strong preference for asparagine residue at the S2 subsite of Stenotrophomonas maltophilia dipeptidyl peptidase 7
- Akihiro Nakamura
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Pactacin is a novel digestive enzyme in teleosts
- Mari Kawaguchi
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Inhibition of ERK 1/2 kinases prevents tendon matrix breakdown
- Ulrich Blache
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Serum C-reactive protein metabolite (CRPM) is associated with incidence of contralateral knee osteoarthritis
- Anne-Christine Bay-Jensen
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Nitrocellulose-bound achromopeptidase for point-of-care nucleic acid tests
- Georgios Chondrogiannis
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Redox signaling through zinc activates the radiation response in Deinococcus bacteria
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Cohnella 1759 cysteine protease shows significant long term half-life and impressive increased activity in presence of some chemical reagents
- Rayan Saghian
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Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2
- Ewelina Weglarz-Tomczak
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Bioinformatic mapping of a more precise Aspergillus niger degradome
- Zixing Dong
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Mating-regulated atrial proteases control reinsemination rates in Anopheles gambiae females
- Priscila Bascuñán
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Cathepsin S provokes interleukin-6 (IL-6) trans-signaling through cleavage of the IL-6 receptor in vitro
- Charlotte M. Flynn
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Activation of PAR2 by tissue factor induces the release of the PTEN from MAGI proteins and regulates PTEN and Akt activities
- Mohammad A. Mohammad
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- & Camille Ettelaie
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The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases
- James L. J. Coleman
- , Tony Ngo
- & Nicola J. Smith
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Cell-free synthesis of the hirudin variant 1 of the blood-sucking leech Hirudo medicinalis
- Doreen A. Wüstenhagen
- , Phil Lukas
- & Stefan Kubick
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Identification and characterization of the proteolytic flagellin from the common freshwater bacterium Hylemonella gracilis
- Ulrich Eckhard
- , Constantin Blöchl
- & Hans Brandstetter
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Nanoscale flow cytometry reveals interpatient variability in HIV protease activity that correlates with viral infectivity and identifies drug-resistant viruses
- Michał M. Bonar
- , Caroline O. Tabler
- & John C. Tilton
Network analysis of the proteome and peptidome sheds light on human milk as a biological system