Nanobiotechnology articles within Nature

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  • Article
    | Open Access

    Flow limitation is exploited to develop a microfluidic device exhibiting flow–pressure behaviour analogous to the current–voltage characteristics of an electronic transistor.

    • Kaustav A. Gopinathan
    • , Avanish Mishra
    •  & Mehmet Toner

  • Article |

    Preparing crystals held together with macromolecular bonds can create shape memory materials that can be engineered to exhibit a wide range of reversible changes useful for chemical sensing, optics and robotics.

    • Seungkyu Lee
    • , Heather A. Calcaterra
    •  & Chad A. Mirkin

  • Article
    | Open Access

    Live-seq, a single-cell transcriptome profiling approach that preserves cell viability during RNA extraction using fluidic force microscopy, can address a range of biological questions by transforming scRNA-seq from an end-point to a temporal analysis approach.

    • Wanze Chen
    • , Orane Guillaume-Gentil
    •  & Bart Deplancke

  • Article |

    A modular de novo designed biosensor platform consisting of a cage and key molecule is developed, and used to create sensors for seven distinct proteins including the spike protein from SARS-CoV-2 and anti-SARS antibodies.

    • Alfredo Quijano-Rubio
    • , Hsien-Wei Yeh
    •  & David Baker

  • Article |

    Lateral-flow in vitro diagnostic assays based on fluorescent nanodiamonds, in which microwave-based spin manipulation is used to increase sensitivity, are demonstrated using the biotin–avidin model and by the single-copy detection of HIV-1 RNA.

    • Benjamin S. Miller
    • , Léonard Bezinge
    •  & Rachel A. McKendry

  • Article |

    The building blocks of the nanostructures observed on Drosophila corneas are determined, and then used to create artificial nanostructures with anti-reflective and anti-adhesive properties.

    • Mikhail Kryuchkov
    • , Oleksii Bilousov
    •  & Vladimir L. Katanaev

  • Letter |

    Computationally designed icosahedral protein-based assemblies can protect their genetic material and evolve in biochemical environments, suggesting a route to the custom design of synthetic nanomaterials for non-viral drug delivery.

    • Gabriel L. Butterfield
    • , Marc J. Lajoie
    •  & David Baker

  • Letter |

    By using DNA sequence information to encode the shapes of DNA origami building blocks, shape-programmable assemblies can be created, with sizes and complexities similar to those of viruses.

    • Klaus F. Wagenbauer
    • , Christian Sigl
    •  & Hendrik Dietz

  • Letter |

    All necessary strands for DNA origami can be created in a single scalable process by using bacteriophages to generate single-stranded precursor DNA containing the target sequences interleaved with self-excising DNA enzymes.

    • Florian Praetorius
    • , Benjamin Kick
    •  & Hendrik Dietz

  • Letter |

    Rotary molecular machines, activated by ultraviolet light, are able to perturb and drill into cell membranes in a controllable manner, and more efficiently than those exhibiting flip-flopping or random motion.

    • Víctor García-López
    • , Fang Chen
    •  & James M. Tour

  • Letter |

    The authors report a new biomimetic nanodelivery platform in which polymeric nanoparticles enclosed in the plasma membrane of human platelets are used for disease-relevant targeting, and the therapeutic potential of the concept is demonstrated in animal models of coronary restenosis and systemic bacterial infection.

    • Che-Ming J. Hu
    • , Ronnie H. Fang
    •  & Liangfang Zhang

  • Letter |

    Short carbon nanotubes spontaneously insert into lipid bilayers and live cell membranes to form channels with useful and tunable transport properties that make them a promising biomimetic nanopore platform for developing cell interfaces, studying nanofluidic transport in biological channels, and creating stochastic sensors.

    • Jia Geng
    • , Kyunghoon Kim
    •  & Aleksandr Noy

  • Outlook |

    New antibiotic treatments could be found by combining novel and existing drugs, in drug-free nanoparticles, or at the bottom of the sea.

    • Katharine Gammon

  • Letter |

    Single magnetic atoms on non-magnetic surfaces have magnetic moments that are usually destabilized within a microsecond, too speedily to be useful, but here the magnetic moments of single holmium atoms on a highly conductive metallic substrate can reach lifetimes of the order of minutes.

    • Toshio Miyamachi
    • , Tobias Schuh
    •  & Wulf Wulfhekel

  • Letter |

    A nanoscale thermometry technique that uses coherent manipulation of the electronic spin associated with nitrogen–vacancy colour centres in diamond makes it possible to detect temperature variations as small as 1.8 millikelvin in ultrapure samples and to control and map temperature gradients within living cells.

    • G. Kucsko
    • , P. C. Maurer
    •  & M. D. Lukin

  • News & Views |

    To understand how blood vessels form and function, scientists require reproducible systems that mimic living tissues. An innovative approach based on microfabricated vessels provides a key step towards this goal.

    • Claudio Franco
    •  & Holger Gerhardt

  • Letter |

    Uniformly sized, structured spherical particles can be made in large quantities and across a wide range of sizes by an ingenious technique involving heating and drawing out multi-component fibres.

    • Joshua J. Kaufman
    • , Guangming Tao
    •  & Ayman F. Abouraddy

  • Letter |

    Propagating cracks—normally associated with material failure and viewed as undesirable—can be controlled in a film/substrate system, opening up new possibilities for nanofabrication and atomic-scale patterning.

    • Koo Hyun Nam
    • , Il H. Park
    •  & Seung Hwan Ko

  • Letter |

    Experiments using ultrafast mid-infrared light pulses on nanostructures access a new regime in photoelectron emission, revealing classical sub-cycle electron dynamics in optical near-fields and breaking a diffraction limit in strong-field physics.

    • G. Herink
    • , D. R. Solli
    •  & C. Ropers

  • News & Views |

    Current methods for screening libraries of compounds for biological activity are rather cumbersome, slow and imprecise. A method that breaks up a continuous flow of a compound's solution into droplets offers radical improvements.

    • Robert C. R. Wootton
    •  & Andrew J. deMello

  • Article |

    Thousands of quorum-sensing Escherichia coli colonies are synchronized over centimetres using redox signalling to create ‘biopixels’ that can sense trace amounts of arsenic in water.

    • Arthur Prindle
    • , Phillip Samayoa
    •  & Jeff Hasty

  • News & Views |

    Nanoscale systems designed to imitate functions from the macroscopic world lead to a new appreciation of the complexity needed to actuate motion at the limits of miniaturization. A nanoscale 'car' is the latest example. See Letter p.208

    • Paul S. Weiss

  • News & Views |

    A simple peptide that assembles into desirable nanoscale structures is a striking example of how the whole can be greater than the sum of its parts. What's more, the assembly process is controllably reversible.

    • Charlotte A. E. Hauser
    •  & Shuguang Zhang

  • News & Views |

    The resonant behaviour of clusters of gold nanoparticles has been tuned by gradually bringing the particles together. The approach could have many applications, including chemical and biological sensing.

    • Mark I. Stockman

  • News & Views |

    Nanoparticles that generate light through a mechanism known as second harmonic generation have been used to image live tissue. The particles overcome many problems associated with fluorescent probes for bioimaging.

    • Bruce E. Cohen

  • News |

    Spiralling electron beams have the potential to measure and manipulate the properties of single atoms.

    • Zeeya Merali

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