Featured
-
-
Article
| Open AccessSCFβTrCP-mediated degradation of SHARP1 in triple-negative breast cancer
- Juliana Haydeé Enriqué Steinberg
- , Fabiana Alejandra Rossi
- & Angela Lauriola
-
Article
| Open AccessPyruvate dehydrogenase kinase 1 protects against neuronal injury and memory loss in mouse models of diabetes
- Yuan Yao
- , Jiaming Shi
- & Liang Kong
-
Article
| Open AccessDUSP1 protects against ischemic acute kidney injury through stabilizing mtDNA via interaction with JNK
- Lang Shi
- , Hongchu Zha
- & Jiefu Zhu
-
Article
| Open AccessPyrroloquinoline quinone inhibits PCSK9-NLRP3 mediated pyroptosis of Leydig cells in obese mice
- Jinyuan Wang
- , Shun Zhang
- & Xiaocan Lei
-
Review Article
| Open AccessMesenchymal stem cells under epigenetic control – the role of epigenetic machinery in fate decision and functional properties
- Alicja Walewska
- , Adrian Janucik
- & Andrzej Eljaszewicz
-
Article
| Open AccessSAA suppresses α-PD-1 induced anti-tumor immunity by driving TH2 polarization in lung adenocarcinoma
- Xin Wang
- , Shaodi Wen
- & Bo Shen
-
Article
| Open AccessInhibition of LSD1 induces ferroptosis through the ATF4-xCT pathway and shows enhanced anti-tumor effects with ferroptosis inducers in NSCLC
- Linna Du
- , Han Yang
- & Pengxing He
-
Article
| Open AccessPrph2 knock-in mice recapitulate human central areolar choroidal dystrophy retinal degeneration and exhibit aberrant synaptic remodeling and microglial activation
- María José Ruiz-Pastor
- , Xavier Sánchez-Sáez
- & Nicolás Cuenca
-
Article
| Open AccessFTO-mediated LINC01134 stabilization to promote chemoresistance through miR-140-3p/WNT5A/WNT pathway in PDAC
- Jin Lu
- , Yongsheng Yang
- & Zefeng Liu
-
Article
| Open AccessN4-acetylcytidine-dependent GLMP mRNA stabilization by NAT10 promotes head and neck squamous cell carcinoma metastasis and remodels tumor microenvironment through MAPK/ERK signaling pathway
- Yuanyuan Liu
- , Xing Wang
- & Pin Dong
-
Article
| Open AccessTargeting mPGES-2 to protect against acute kidney injury via inhibition of ferroptosis dependent on p53
- Dandan Zhong
- , Lingling Quan
- & Ying Sun
-
Article
| Open AccessTalin-1 inhibits Smurf1-mediated Stat3 degradation to modulate β-cell proliferation and mass in mice
- Xiaoting Hou
- , Yangshan Chen
- & Huiling Cao
-
Article
| Open AccessThe microprotein encoded by exosomal lncAKR1C2 promotes gastric cancer lymph node metastasis by regulating fatty acid metabolism
- Ke-Gan Zhu
- , Jiayu Yang
- & Hai-Yang Zhang
-
Article
| Open AccessLoss of adenosine A3 receptors accelerates skeletal muscle regeneration in mice following cardiotoxin-induced injury
- Nastaran Tarban
- , Albert Bálint Papp
- & Zsuzsa Szondy
-
Article
| Open AccessTargeting cancer-associated adipocyte-derived CXCL8 inhibits triple-negative breast cancer progression and enhances the efficacy of anti-PD-1 immunotherapy
- Renhong Huang
- , Zheng Wang
- & Kunwei Shen
-
Article
| Open AccessSalicylate induces AMPK and inhibits c-MYC to activate a NRF2/ARE/miR-34a/b/c cascade resulting in suppression of colorectal cancer metastasis
- Chunfeng Liu
- , Matjaz Rokavec
- & Heiko Hermeking
-
-
Article
| Open AccessNeuron-secreted NLGN3 ameliorates ischemic brain injury via activating Gαi1/3-Akt signaling
- Zhi-guo Chen
- , Xin Shi
- & Ya Peng
-
Article
| Open AccessDNAJA4 suppresses epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma via PSMD2-mediated MYH9 degradation
- Qun Zhang
- , Ping Feng
- & Ying-Qing Li
-
Article
| Open AccessSohlh2 promotes pulmonary fibrosis via repression of p62/Keap1/Nrf2 mediated anti-oxidative signaling pathway
- Lanlan Liu
- , Xiaoli Zhang
- & Jing Hao
-
Article
| Open AccessLong non-coding RNA NRSN2-AS1 promotes ovarian cancer progression through targeting PTK2/β-catenin pathway
- Yi-Bo Wu
- , Shen-Yi Li
- & Cong Shen
-
Review Article
| Open AccessMacrophage polarization and metabolism in atherosclerosis
- Pengbo Hou
- , Jiankai Fang
- & Gerry Melino
-
Article
| Open AccessInherited myogenic abilities in muscle precursor cells defined by the mitochondrial complex I-encoding protein
- Norio Motohashi
- , Katsura Minegishi
- & Yoshitsugu Aoki
-
Article
| Open AccessLAIR1 drives glioma progression by nuclear focal adhesion kinase dependent expressions of cyclin D1 and immunosuppressive chemokines/cytokines
- Xiaoqian Wei
- , Shushan Pan
- & Huanli Xu
-
Article
| Open AccessDARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma
- Alexander Strubel
- , Philipp Münick
- & Volker Dötsch
-
Article
| Open AccessKidney tubular epithelial cells control interstitial fibroblast fate by releasing TNFAIP8-encapsulated exosomes
- Xi Liu
- , Zhao Liu
- & Youhua Liu
-
Article
| Open AccessMacrophages originated IL-33/ST2 inhibits ferroptosis in endometriosis via the ATF3/SLC7A11 axis
- Qiong Wu
- , Zongwen Liang
- & Yingying Cao
-
Article
| Open AccessIdentification of the mitochondrial protein POLRMT as a potential therapeutic target of prostate cancer
- Xiaojun Li
- , Linya Yao
- & Ting Jiang
-
Article
| Open AccessSYVN1-mediated ubiquitylation directs localization of MCT4 in the plasma membrane to promote the progression of lung adenocarcinoma
- Meng Zhao
- , Chen Huang
- & Li Ren
-
Article
| Open AccessPyruvate kinase M2 regulates mitochondrial homeostasis in cisplatin-induced acute kidney injury
- Wenjia Xie
- , Qingyun He
- & Lei Jiang
-
Article
| Open AccessInhibition of mitochondrial fission activates glycogen synthesis to support cell survival in colon cancer
- Sumati Hasani
- , Lyndsay E. A. Young
- & Tianyan Gao
-
Article
| Open AccessJMJD5 inhibits lung cancer progression by facilitating EGFR proteasomal degradation
- Jing Shen
- , Guiling Liu
- & Jimin Shao
-
Article
| Open AccessPolyphenol-rich diet mediates interplay between macrophage-neutrophil and gut microbiota to alleviate intestinal inflammation
- Dandan Han
- , Yujun Wu
- & Junjun Wang
-
Article
| Open AccessFallopian tube lesions as potential precursors of early ovarian cancer: a comprehensive proteomic analysis
- Maxence Wisztorski
- , Soulaimane Aboulouard
- & Michel Salzet
-
Article
| Open AccessSIRT2 alleviated renal fibrosis by deacetylating SMAD2 and SMAD3 in renal tubular epithelial cells
- Shu Yang
- , Guangyan Yang
- & Zhen Liang
-
Article
| Open AccessTargeting cis-regulatory elements of FOXO family is a novel therapeutic strategy for induction of leukemia cell differentiation
- Kenta Kurayoshi
- , Yusuke Takase
- & Atsushi Hirao
-
Article
| Open AccessRNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer
- Evangelos Prokakis
- , Shaishavi Jansari
- & Florian Wegwitz
-
Article
| Open AccessYAP1 expression is associated with survival and immunosuppression in small cell lung cancer
- Peixin Chen
- , Chenglong Sun
- & Yayi He
-
Article
| Open AccessPPM1K mediates metabolic disorder of branched-chain amino acid and regulates cerebral ischemia-reperfusion injury by activating ferroptosis in neurons
- Tao Li
- , Lili Zhao
- & Guilian Zhang
-
Article
| Open AccessThe oleic/palmitic acid imbalance in exosomes isolated from NAFLD patients induces necroptosis of liver cells via the elongase-6/RIP-1 pathway
- Maria Principia Scavo
- , Roberto Negro
- & Gianluigi Giannelli
-
Article
| Open AccessREPIN1 regulates iron metabolism and osteoblast apoptosis in osteoporosis
- Yu Xia
- , Gaoran Ge
- & Dechun Geng
-
Review Article
| Open AccessHearing loss and vestibular schwannoma: new insights into Schwann cells implication
- Tasnim Mohamed
- , Valentina Melfi
- & Valerio Magnaghi
-
Article
| Open AccessMethylation of BRD4 by PRMT1 regulates BRD4 phosphorylation and promotes ovarian cancer invasion
- Yi Liu
- , Hejing Liu
- & Xueqiong Zhu
-
Review Article
| Open AccessEmerging significance and therapeutic targets of ferroptosis: a potential avenue for human kidney diseases
- Jinghan Li
- , Sujuan Zheng
- & Ke Tan
-
Article
| Open AccessA new scaffold-free tumoroid model provides a robust preclinical tool to investigate invasion and drug response in Renal Cell Carcinoma
- Irinka Séraudie
- , Catherine Pillet
- & Odile Filhol
-
Article
| Open AccessHepatic T-cell senescence and exhaustion are implicated in the progression of fatty liver disease in patients with type 2 diabetes and mouse model with nonalcoholic steatohepatitis
- Byeong Chang Sim
- , Yea Eun Kang
- & Hyon-Seung Yi
-
Article
| Open AccessSCF and IL-33 regulate mouse mast cell phenotypic and functional plasticity supporting a pro-inflammatory microenvironment
- Rosa Molfetta
- , Mario Lecce
- & Rossella Paolini
-
Article
| Open AccessInhibition of cGAS–STING pathway alleviates neuroinflammation-induced retinal ganglion cell death after ischemia/reperfusion injury
- Xingdi Wu
- , Naiji Yu
- & Kaijun Wang
-
Article
| Open AccessCRNDE mediated hnRNPA2B1 stability facilitates nuclear export and translation of KRAS in colorectal cancer
- Ya Lu
- , Renrui Zou
- & Yuan Zhang