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Open Access
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Original Article
| Open AccessInhibition of autophagy prevents irradiation-induced neural stem and progenitor cell death in the juvenile mouse brain
- Yafeng Wang
- , Kai Zhou
- & Changlian Zhu
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Original Article
| Open AccessSolute carrier family 12 member 5 promotes tumor invasion/metastasis of bladder urothelial carcinoma by enhancing NF-κB/MMP-7 signaling pathway
- J Y Liu
- , Y B Dai
- & L Y He
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Original Article
| Open AccessNCAPH plays important roles in human colon cancer
- Liang Yin
- , Li-Ping Jiang
- & Yong-Bin Chen
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Original Article
| Open AccessGanetespib synergizes with cyclophosphamide to improve survival of mice with autochthonous tumors in a mutant p53-dependent manner
- Evguenia M Alexandrova
- , Sulan Xu
- & Ute M Moll
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Original Article
| Open AccessLong noncoding RNA BLACAT1 indicates a poor prognosis of colorectal cancer and affects cell proliferation by epigenetically silencing of p15
- Jun Su
- , Erbao Zhang
- & Dong Shen
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Original Article
| Open AccessThioridazine enhances sensitivity to carboplatin in human head and neck cancer cells through downregulation of c-FLIP and Mcl-1 expression
- Seung Un Seo
- , Hyuk Ki Cho
- & Taeg Kyu Kwon
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Original Article
| Open AccessNLRP3 inflammasome activation mediates radiation-induced pyroptosis in bone marrow-derived macrophages
- Yan-gang Liu
- , Ji-kuai Chen
- & Guo-cai Lu
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Original Article
| Open AccessIncrease in the radioresistance of normal skin fibroblasts but not tumor cells by mechanical injury
- Zelin Chen
- , Xin Wang
- & Chunmeng Shi
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Review
| Open AccessStatins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers
- Christian Henninger
- & Gerhard Fritz
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Original Article
| Open AccessBerberine-sonodynamic therapy induces autophagy and lipid unloading in macrophage
- Jiayuan Y Kou
- , Ying Li
- & Liming M Yang
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Original Article
| Open AccessHuman adipose stem cell differentiation is highly affected by cancer cells both in vitro and in vivo: implication for autologous fat grafting
- Francesca Paino
- , Marcella La Noce
- & Virginia Tirino
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Original Article
| Open AccessCurcumin represses mouse 3T3-L1 cell adipogenic differentiation via inhibiting miR-17-5p and stimulating the Wnt signalling pathway effector Tcf7l2
- Lili Tian
- , Zhuolun Song
- & Tianru Jin
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Original Article
| Open AccessAutophagy dysregulation in Danon disease
- Anna Chiara Nascimbeni
- , Marina Fanin
- & Marco Sandri
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Original Article
| Open AccessHepatitis B virus X protein promotes the stem-like properties of OV6+ cancer cells in hepatocellular carcinoma
- Chao Wang
- , Ming-da Wang
- & Wei-ping Zhou
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Original Article
| Open AccessHIF-2α and Oct4 have synergistic effects on survival and myocardial repair of very small embryonic-like mesenchymal stem cells in infarcted hearts
- Shaoheng Zhang
- , Lan Zhao
- & Xin Pan
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Original Article
| Open AccessDysfunctional autophagy in RPE, a contributing factor in age-related macular degeneration
- Nady Golestaneh
- , Yi Chu
- & Alexander C Theos
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Original Article
| Open AccessHuman umbilical cord blood-stem cells direct macrophage polarization and block inflammasome activation to alleviate rheumatoid arthritis
- Tae-Hoon Shin
- , Hyung-Sik Kim
- & Kyung-Sun Kang
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Original Article
| Open AccessDownregulated expression of microRNA-124 in pediatric intestinal failure patients modulates macrophages activation by inhibiting STAT3 and AChE
- Yong-Tao Xiao
- , Jun Wang
- & Wei Cai
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Original Article
| Open AccessDual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC
- Jae-Seon Lee
- , Joon H Kang
- & Soo-Youl Kim
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Original Article
| Open AccessHyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation
- Madhulika Tripathi
- , Cheng Wu Zhang
- & Paul Michael Yen
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Original Article
| Open AccessCombined nifuroxazide and SAT05f therapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation
- Huijie Jia
- , Tiesuo Zhao
- & Kailin Xu
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Original Article
| Open AccessInflammatory macrophages can transdifferentiate into myofibroblasts during renal fibrosis
- Xiao-Ming Meng
- , Shuang Wang
- & Hui-Yao Lan
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Original Article
| Open AccessTherapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer’s disease models
- Stuart A Lipton
- , Tayebeh Rezaie
- & Nobuki Nakanishi
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Original Article
| Open Access1-Methyl-tryptophan attenuates regulatory T cells differentiation due to the inhibition of estrogen-IDO1-MRC2 axis in endometriosis
- Chunyan Wei
- , Jie Mei
- & Xiaoyong Zhu
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Original Article
| Open AccessA mechanism for overcoming P-glycoprotein-mediated drug resistance: novel combination therapy that releases stored doxorubicin from lysosomes via lysosomal permeabilization using Dp44mT or DpC
- Nicole A Seebacher
- , Des R Richardson
- & Patric J Jansson
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Review
| Open AccessEmerging roles of extracellular vesicles in neurodegenerative disorders: focus on HIV-associated neurological complications
- Guoku Hu
- , Lu Yang
- & Shilpa Buch
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Original Article
| Open AccessArginase 2 promotes neurovascular degeneration during ischemia/reperfusion injury
- Esraa Shosha
- , Zhimin Xu
- & S Priya Narayanan
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Original Article
| Open AccessLithium promotes DNA stability and survival of ischemic retinal neurocytes by upregulating DNA ligase IV
- Ying Yang
- , Nandan Wu
- & Jing Zhuang
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Original Article
| Open AccessDe-ubiquitinating enzyme, USP11, promotes transforming growth factor β-1 signaling through stabilization of transforming growth factor β receptor II
- A M Jacko
- , L Nan
- & Y Zhao
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Original Article
| Open AccessRapidly cycling Lgr5+ stem cells are exquisitely sensitive to extrinsic dietary factors that modulate colon cancer risk
- Eunjoo Kim
- , Laurie A Davidson
- & Robert S Chapkin
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Review
| Open AccessThe control of male fertility by spermatid-specific factors: searching for contraceptive targets from spermatozoon’s head to tail
- Su-Ren Chen
- , Aalia Batool
- & Yi-Xun Liu
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Original Article
| Open AccessCysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation
- Álvaro de Mingo
- , Estefanía de Gregorio
- & Montserrat Marí
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Original Article
| Open AccessDoxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death
- Chih-Yang Huang
- , Wei-Wen Kuo
- & Chih-Yang Huang
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Original Article
| Open AccessPAR2 regulates regeneration, transdifferentiation, and death
- Ron Piran
- , Seung-Hee Lee
- & Fred Levine
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Original Article
| Open AccessThe prosurvival protein BAG3: a new participant in vascular homeostasis
- Albino Carrizzo
- , Antonio Damato
- & Carmine Vecchione
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Original Article
| Open Access1, 25-dihydroxy-vitamin D3 with tumor necrosis factor-alpha protects against rheumatoid arthritis by promoting p53 acetylation-mediated apoptosis via Sirt1 in synoviocytes
- Xin Gu
- , Bingjie Gu
- & Jianliang Jin
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Original Article
| Open AccessLoss of Rictor with aging in osteoblasts promotes age-related bone loss
- Pinling Lai
- , Qiancheng Song
- & Xiaochun Bai
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Original Article
| Open AccessCnbp ameliorates Treacher Collins Syndrome craniofacial anomalies through a pathway that involves redox-responsive genes
- Mauro S Porcel de Peralta
- , Valeria S Mouguelar
- & Nora B Calcaterra
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Original Article
| Open AccessAttenuated DNA damage repair delays therapy-related myeloid neoplasms in a mouse model
- Kit I Tong
- , Kazushige Ota
- & Hitoshi Okada
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Original Article
| Open AccessMesenchymal stem cells stimulate intestinal stem cells to repair radiation-induced intestinal injury
- Wei Gong
- , Mengzheng Guo
- & Qiang Liu
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Review
| Open AccessLong noncoding RNAs in the progression, metastasis, and prognosis of osteosarcoma
- Zuozhang Yang
- , Xiaojuan Li
- & Ya Zhang
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Original Article
| Open AccessRETRACTED ARTICLE: Hsa-miR-623 suppresses tumor progression in human lung adenocarcinoma
- Shuang Wei
- , Zun-yi Zhang
- & Wei-ning Xiong
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News and Commentary
| Open AccessOxidative downmodulation of T cell-mediated cytotoxicity
- Guido H Wabnitz
- & Yvonne Samstag
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Original Article
| Open Access4-cholesten-3-one suppresses lung adenocarcinoma metastasis by regulating translocation of HMGB1, HIF1α and Caveolin-1
- Jinben Ma
- , Guobin Fu
- & Yibing Wang
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Original Article
| Open AccessThrombospondin-1 signaling through CD47 inhibits cell cycle progression and induces senescence in endothelial cells
- Qi Gao
- , Kexin Chen
- & Yong-Guang Yang
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Original Article
| Open AccessMiR-182-5p protects inner ear hair cells from cisplatin-induced apoptosis by inhibiting FOXO3a
- Yimeng Li
- , Ao Li
- & Huawei Li
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Original Article
| Open AccessRet is essential to mediate GDNF’s neuroprotective and neuroregenerative effect in a Parkinson disease mouse model
- Anja Drinkut
- , Karsten Tillack
- & Edgar R Kramer
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Original Article
| Open AccessMCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL
- Ingela B Vikström
- , Anne Slomp
- & David M Tarlinton
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Original Article
| Open AccessLuteolin-7-glucoside inhibits IL-22/STAT3 pathway, reducing proliferation, acanthosis, and inflammation in keratinocytes and in mouse psoriatic model
- R Palombo
- , I Savini
- & A Terrinoni