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Open Access
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Original Article
| Open AccessTissue transglutaminase (TG2) enables survival of human malignant pleural mesothelioma cells in hypoxia
- Sara Zonca
- , Giulia Pinton
- & Laura Moro
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Original Article
| Open AccessProteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor
- Yuning Liao
- , Ningning Liu
- & Jinbao Liu
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Review
| Open AccessStatins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers
- Christian Henninger
- & Gerhard Fritz
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Original Article
| Open AccessHeme oxygenase-1 in the forefront of a multi-molecular network that governs cell–cell contacts and filopodia-induced zippering in prostate cancer
- Alejandra V Paez
- , Carla Pallavicini
- & Geraldine Gueron
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Original Article
| Open AccessImpaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice
- Swati Dawar
- , Nur Hezrin Shahrin
- & Sharad Kumar
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Original Article
| Open AccessSUMO-specific protease 1 protects neurons from apoptotic death during transient brain ischemia/reperfusion
- Huijun Zhang
- , Yan Wang
- & Yong Li
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Original Article
| Open AccessNeutral sphingomyelinase (SMPD3) deficiency disrupts the Golgi secretory pathway and causes growth inhibition
- Wilhelm Stoffel
- , Ina Hammels
- & Frank Zaucke
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Original Article
| Open AccessLithium promotes DNA stability and survival of ischemic retinal neurocytes by upregulating DNA ligase IV
- Ying Yang
- , Nandan Wu
- & Jing Zhuang
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Original Article
| Open AccessDe-ubiquitinating enzyme, USP11, promotes transforming growth factor β-1 signaling through stabilization of transforming growth factor β receptor II
- A M Jacko
- , L Nan
- & Y Zhao
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Original Article
| Open AccessRIPK1 protects from TNF-α-mediated liver damage during hepatitis
- Aveline Filliol
- , Claire Piquet-Pellorce
- & Michel Samson
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Original Article
| Open AccessThe V-ATPase a2 isoform controls mammary gland development through Notch and TGF-β signaling
- Sahithi Pamarthy
- , Liquin Mao
- & Kenneth D Beaman
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Original Article
| Open AccessDDX3 DEAD-box RNA helicase plays a central role in mitochondrial protein quality control in Leishmania
- Prasad Kottayil Padmanabhan
- , Ouafa Zghidi-Abouzid
- & Barbara Papadopoulou
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Original Article
| Open AccessKinase-independent function of RIP1, critical for mature T-cell survival and proliferation
- John P Dowling
- , Yubo Cai
- & Jianke Zhang
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Original Article
| Open AccessActivation of salt-inducible kinase 2 promotes the viability of peritoneal mesothelial cells exposed to stress of peritoneal dialysis
- H-H Wang
- , C-Y Lin
- & C-J Chang
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Original Article
| Open AccessMps1 kinase regulates tumor cell viability via its novel role in mitochondria
- X Zhang
- , Y Ling
- & R Z Ma
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Review
| Open AccessFatty acid oxidation and carnitine palmitoyltransferase I: emerging therapeutic targets in cancer
- Q Qu
- , F Zeng
- & F Deng
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Original Article
| Open AccessStalled replication forks within heterochromatin require ATRX for protection
- M S Huh
- , D Ivanochko
- & D J Picketts
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Original Article
| Open AccessIschemic postconditioning protects the heart against ischemia–reperfusion injury via neuronal nitric oxide synthase in the sarcoplasmic reticulum and mitochondria
- L Hu
- , J Wang
- & Q Li
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Original Article
| Open AccessInhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis
- S Neitemeier
- , A M Dolga
- & C Culmsee
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Original Article
| Open AccessGlutathione peroxidase 1 deficiency attenuates concanavalin A-induced hepatic injury by modulation of T-cell activation
- D H Lee
- , D J Son
- & J T Hong
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News and Commentary
| Open AccessDiscovery of a novel target for renal cell carcinoma: transglutaminase 2
- J H Kang
- , S-H Lee
- & S-Y Kim
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Original Article
| Open AccessWee1 inhibition potentiates Wip1-dependent p53-negative tumor cell death during chemotherapy
- V Clausse
- , A R Goloudina
- & O N Demidov
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Original Article
| Open AccessOverexpression of human kynurenine-3-monooxygenase protects against 3-hydroxykynurenine-mediated apoptosis through bidirectional nonlinear feedback
- K Wilson
- , M Auer
- & D J Mole
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News and Commentary
| Open AccessCathepsin B pulls the emergency brake on cellular necrosis
- F S Wouters
- & G Bunt
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News and Commentary
| Open AccessPreventing cell death with a ‘check valve’ in mitochondrial complex I?
- E Fontaine
- , D Detaille
- & G Vial
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Original Article
| Open AccessParp mutations protect against mitochondrial dysfunction and neurodegeneration in a PARKIN model of Parkinson’s disease
- S Lehmann
- , A C Costa
- & L M Martins
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Original Article
| Open AccessRenal cell carcinoma escapes death by p53 depletion through transglutaminase 2-chaperoned autophagy
- J H Kang
- , J-S Lee
- & S-Y Kim
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Original Article
| Open AccessLong non-coding RNA C2dat1 regulates CaMKIIδ expression to promote neuronal survival through the NF-κB signaling pathway following cerebral ischemia
- Q Xu
- , F Deng
- & A Ji
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Original Article
| Open AccessPoly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation
- C Wang
- , C Qu
- & G Mbalaviele
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News and Commentary
| Open AccessNGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells
- P Ruggeri
- , L Cappabianca
- & A R Mackay
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Original Article
| Open AccessAlkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system
- K Wang
- , R Xu
- & C Mao
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Original Article
| Open AccessTumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by downregulation of MMP2 and inactivation of ERK/MAPK signaling
- Y Han
- , Z Wu
- & Z Du
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Original Article
| Open AccessNicotinamide mononucleotide adenylyltransferase promotes hypoxic survival by activating the mitochondrial unfolded protein response
- X R Mao
- , D M Kaufman
- & C M Crowder
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Correspondence
| Open AccessLoss of Merlin/NF2 protects pancreatic β-cells from apoptosis by inhibiting LATS2
- T Yuan
- , K D D Gorrepati
- & A Ardestani
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Original Article
| Open AccessCaspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease
- M V Machado
- , G A Michelotti
- & A M Diehl
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Original Article
| Open AccessLow levels of Caspase-3 predict favourable response to 5FU-based chemotherapy in advanced colorectal cancer: Caspase-3 inhibition as a therapeutic approach
- L Flanagan
- , M Meyer
- & J H M Prehn
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News and Commentary
| Open AccessCaspase 8 expression may determine the survival of women with ovarian cancer
- M Kim
- , L Hernandez
- & C M Annunziata
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Original Article
| Open AccessTargeting caspase-6 and caspase-8 to promote neuronal survival following ischemic stroke
- A P Shabanzadeh
- , P M D'Onofrio
- & P D Koeberle
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Original Article
| Open AccessImplication of different domains of the Leishmania major metacaspase in cell death and autophagy
- M Casanova
- , I J Gonzalez
- & N Fasel
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Original Article
| Open AccessConformations of tissue plasminogen activator (tPA) orchestrate neuronal survival by a crosstalk between EGFR and NMDAR
- T Bertrand
- , F Lesept
- & D Vivien
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News and Commentary
| Open AccessDrilling into RIP1 biology: what compounds are in your toolkit?
- S B Berger
- , J Bertin
- & P J Gough
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News and Commentary
| Open AccessPreventing ototoxic hearing loss by inhibiting histone deacetylases
- W S Layman
- & J Zuo
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Original Article
| Open AccessTransglutaminase 2—a novel inhibitor of adipogenesis
- V D Myneni
- , G Melino
- & M T Kaartinen
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Original Article
| Open Accessp53- and p73-independent activation of TIGAR expression in vivo
- P Lee
- , A K Hock
- & E C Cheung
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Original Article
| Open AccessRole of acid sphingomyelinase bioactivity in human CD4+ T-cell activation and immune responses
- A Bai
- , E Kokkotou
- & S C Robson
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Original Article
| Open AccessSingle-cell imaging of inflammatory caspase dimerization reveals differential recruitment to inflammasomes
- M G Sanders
- , M J Parsons
- & L Bouchier-Hayes
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Original Article
| Open AccessHistone acetyltransferase PCAF accelerates apoptosis by repressing a GLI1/BCL2/BAX axis in hepatocellular carcinoma
- X Gai
- , K Tu
- & X Zheng