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| Open AccessWTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2
- Teresa Maria Carusone
- , Giovanna Cardiero
- & Giuseppe Manco
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Original Article
| Open AccessCircular RNA expression is suppressed by androgen receptor (AR)-regulated adenosine deaminase that acts on RNA (ADAR1) in human hepatocellular carcinoma
- Liang Shi
- , Peijian Yan
- & Xiujun Cai
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Original Article
| Open AccessCaspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity
- Claire H Wilson
- , Andrej Nikolic
- & Sharad Kumar
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Original Article
| Open AccessInhibition of Caspase-8 does not protect from alcohol-induced liver apoptosis but alleviates alcoholic hepatic steatosis in mice
- Fengjie Hao
- , Francisco Javier Cubero
- & Yulia A Nevzorova
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Original Article
| Open AccessReciprocal amplification of caspase-3 activity by nuclear export of a putative human RNA-modifying protein, PUS10 during TRAIL-induced apoptosis
- Sujata Jana
- , Andrew C Hsieh
- & Ramesh Gupta
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Original Article
| Open AccessExecutioner caspases and CAD are essential for mutagenesis induced by TRAIL or vincristine
- Mark A Miles
- & Christine J Hawkins
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Original Article
| Open AccessKnockdown of SIRT7 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the Wnt/β-catenin signaling pathway
- Erman E M Chen
- , Wei Zhang
- & Deting D T Xue
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Original Article
| Open AccessKlotho enhances FoxO3-mediated manganese superoxide dismutase expression by negatively regulating PI3K/AKT pathway during tacrolimus-induced oxidative stress
- Sun Woo Lim
- , Long Jin
- & Chul Woo Yang
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Review
| Open AccessAcid sphingomyelinase mediates human CD4+ T-cell signaling: potential roles in T-cell responses and diseases
- Aiping Bai
- & Yuan Guo
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Original Article
| Open AccessHistone deacetylase 3 overexpression in human cholangiocarcinoma and promotion of cell growth via apoptosis inhibition
- Yuyao Yin
- , Mingming Zhang
- & Xiaoping Zou
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Original Article
| Open AccessOocyte-specific deletion of furin leads to female infertility by causing early secondary follicle arrest in mice
- Tie-Gang Meng
- , Meng-Wen Hu
- & Qing-Yuan Sun
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Original Article
| Open AccessDamage-induced neuronal endopeptidase (DINE) enhances axonal regeneration potential of retinal ganglion cells after optic nerve injury
- Aoi Kaneko
- , Sumiko Kiryu-Seo
- & Hiroshi Kiyama
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Original Article
| Open AccessRACK1 depletion in the ribosome induces selective translation for non-canonical autophagy
- Hag Dong Kim
- , EunBin Kong
- & Joon Kim
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Original Article
| Open AccessDrosophila caspase activity is required independently of apoptosis to produce active TNF/Eiger during nociceptive sensitization
- Juyeon Jo
- , Seol Hee Im
- & Michael J Galko
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Original Article
| Open AccessThe role of autophagy in asparaginase-induced immune suppression of macrophages
- Ping Song
- , Ziyu Wang
- & Dianwen Ju
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Original Article
| Open AccessFunctional inhibition of acid sphingomyelinase by Fluphenazine triggers hypoxia-specific tumor cell death
- Saskia Klutzny
- , Ralf Lesche
- & Patrick Steigemann
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News and Commentary
| Open AccessCaspases play in traffic
- Catherine M Duclos
- , Audrey Champagne
- & Jean-Bernard Denault
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Original Article
| Open AccessNuclear Drosha enhances cell invasion via an EGFR-ERK1/2-MMP7 signaling pathway induced by dysregulated miRNA-622/197 and their targets LAMC2 and CD82 in gastric cancer
- Liyun Xu
- , Yixuan Hou
- & Manran Liu
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Original Article
| Open AccessNeuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival
- Theresa M Thole
- , Marco Lodrini
- & Hedwig E Deubzer
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Original Article
| Open AccessMetacaspase-binding peptide inhibits heat shock-induced death in Leishmania (L.) amazonensis
- Mauricio S Peña
- , Guilherme C Cabral
- & Beatriz S Stolf
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News and Commentary
| Open AccessA novel proinflammatory role for granzyme A
- Jacqueline A van Eck
- , Liling Shan
- & Niels Bovenschen
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Original Article
| Open AccessProteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor
- Yuning Liao
- , Ningning Liu
- & Jinbao Liu
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Review
| Open AccessStatins in anthracycline-induced cardiotoxicity: Rac and Rho, and the heartbreakers
- Christian Henninger
- & Gerhard Fritz
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Original Article
| Open AccessImpaired haematopoietic stem cell differentiation and enhanced skewing towards myeloid progenitors in aged caspase-2-deficient mice
- Swati Dawar
- , Nur Hezrin Shahrin
- & Sharad Kumar
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Original Article
| Open AccessNeutral sphingomyelinase (SMPD3) deficiency disrupts the Golgi secretory pathway and causes growth inhibition
- Wilhelm Stoffel
- , Ina Hammels
- & Frank Zaucke
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Original Article
| Open AccessDe-ubiquitinating enzyme, USP11, promotes transforming growth factor β-1 signaling through stabilization of transforming growth factor β receptor II
- A M Jacko
- , L Nan
- & Y Zhao
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Original Article
| Open AccessThe V-ATPase a2 isoform controls mammary gland development through Notch and TGF-β signaling
- Sahithi Pamarthy
- , Liquin Mao
- & Kenneth D Beaman
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Original Article
| Open AccessStalled replication forks within heterochromatin require ATRX for protection
- M S Huh
- , D Ivanochko
- & D J Picketts
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Original Article
| Open AccessAlkaline ceramidase 3 deficiency aggravates colitis and colitis-associated tumorigenesis in mice by hyperactivating the innate immune system
- K Wang
- , R Xu
- & C Mao
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Original Article
| Open AccessTumor-suppressive function of long noncoding RNA MALAT1 in glioma cells by downregulation of MMP2 and inactivation of ERK/MAPK signaling
- Y Han
- , Z Wu
- & Z Du
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Original Article
| Open AccessCaspase-2 promotes obesity, the metabolic syndrome and nonalcoholic fatty liver disease
- M V Machado
- , G A Michelotti
- & A M Diehl
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News and Commentary
| Open AccessPreventing ototoxic hearing loss by inhibiting histone deacetylases
- W S Layman
- & J Zuo
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Original Article
| Open AccessRole of acid sphingomyelinase bioactivity in human CD4+ T-cell activation and immune responses
- A Bai
- , E Kokkotou
- & S C Robson
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Original Article
| Open AccessRestored expression of the atypical heat shock protein H11/HspB8 inhibits the growth of genetically diverse melanoma tumors through activation of novel TAK1-dependent death pathways
- C C Smith
- , K S Lee
- & L Aurelian
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Review
| Open AccessCaspase-1: is IL-1 just the tip of the ICEberg?
- A Denes
- , G Lopez-Castejon
- & D Brough
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Original Article
| Open AccessGranzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737
- V R Sutton
- , K Sedelies
- & N J Waterhouse
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Original Article
| Open AccessCharacterization of a caspase-3-substrate kinome using an N- and C-terminally tagged protein kinase library produced by a cell-free system
- D Tadokoro
- , S Takahama
- & T Sawasaki
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Original Article
| Open AccessResistance to caspase-8 and -9 fragments in a malignant pleural mesothelioma cell line with acquired cisplatin-resistance
- V Janson
- , A Johansson
- & K Grankvist
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Original Article
| Open AccessHistone deacetylase 1 and 2 differentially regulate apoptosis by opposing effects on extracellular signal-regulated kinase 1/2
- W-W Lei
- , K-H Zhang
- & J-G Song