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| Open AccessCombined substituent number utilized machine learning for the development of antimicrobial agent
- Keitaro Yamauchi
- , Hirotaka Nakatsuji
- & Hitoshi Kasai
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| Open AccessTargeting host-virus interactions: in silico analysis of the binding of human milk oligosaccharides to viral proteins involved in respiratory infections
- Anees Ahmed Mahaboob Ali
- , Adarsh Vishal
- & Everette Jacob Remington Nelson
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| Open AccessProcess optimization for green synthesis of silver nanoparticles using Rubus discolor leaves extract and its biological activities against multi-drug resistant bacteria and cancer cells
- Saeed Ghasemi
- , Sara Dabirian
- & Fatemeh Yousefbeyk
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| Open AccessTargeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia
- Henri Colyn Bwanika
- , Isabelle Rose Leo
- & Katja Pokrovskaja Tamm
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| Open AccessToxoflavin analog D43 exerts antiproliferative effects on breast cancer by inducing ROS-mediated apoptosis and DNA damage
- Tingyue Wu
- , Wenjing Liu
- & Ceshi Chen
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| Open AccessCarbon supported ternary layered double hydroxide nanocomposite for Fluoxetine removal and subsequent utilization of spent adsorbent as antidepressant
- Samar M. Mahgoub
- , Doaa Essam
- & Rehab Mahmoud
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| Open AccessProlyl hydroxylase domain inhibitor is an effective pre-hospital pharmaceutical intervention for trauma and hemorrhagic shock
- Xiaowu Wu
- , Andrew P. Cap
- & Michael A. Meledeo
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| Open AccessKaempferol mitigates reproductive dysfunctions induced by Naja nigricollis venom through antioxidant system and anti-inflammatory response in male rats
- Akindele Oluwatosin Adeyi
- , Babafemi Siji Ajisebiola
- & Olukunle Silas Fagbenro
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| Open AccessHIF-2α-dependent TGFBI promotes ovarian cancer chemoresistance by activating PI3K/Akt pathway to inhibit apoptosis and facilitate DNA repair process
- Sijia Ma
- , Jia Wang
- & Le Zhao
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| Open AccessHigh-throughput screening assay for PARP-HPF1 interaction inhibitors to affect DNA damage repair
- Saurabh S. Dhakar
- , Albert Galera-Prat
- & Lari Lehtiö
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| Open AccessRipa-56 protects retinal ganglion cells in glutamate-induced retinal excitotoxic model of glaucoma
- Lemeng Feng
- , Shirui Dai
- & Weitao Song
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| Open Access1H NMR metabolomics insights into comparative diabesity in male and female zebrafish and the antidiabetic activity of DL-limonene
- Khaled Benchoula
- , Christopher J. Serpell
- & Wong Eng Hwa
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| Open AccessPotential Alzheimer’s early biomarkers in a transgenic rat model and benefits of diazoxide/dibenzoylmethane co-treatment on spatial memory and AD-pathology
- Charles H. Wallace
- , Giovanni Oliveros
- & Maria Figueiredo-Pereira
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| Open AccessProtracted molecular dynamics and secondary structure introspection to identify dual-target inhibitors of Nipah virus exerting approved small molecules repurposing
- Siyun Yang
- & Supratik Kar
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| Open AccessFMO-guided design of darunavir analogs as HIV-1 protease inhibitors
- Hathaichanok Chuntakaruk
- , Kowit Hengphasatporn
- & Supot Hannongbua
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| Open AccessRevealing the pharmacological effects of Remodelin against osteosarcoma based on network pharmacology, acRIP-seq and experimental validation
- Jia Gao
- , Peili Xu
- & Lei Fan
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| Open AccessEvaluation of the antidermatophytic activity of potassium salts of N-acylhydrazinecarbodithioates and their aminotriazole-thione derivatives
- Anita Ciesielska
- , Aleksandra Kowalczyk
- & Paweł Stączek
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| Open AccessClinical trials are becoming more complex: a machine learning analysis of data from over 16,000 trials
- Nigel Markey
- , Ben Howitt
- & Christoph Meier
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| Open AccessLytic activity of phages against bacterial pathogens infecting diabetic foot ulcers
- Legesse Garedew Kifelew
- , Morgyn S. Warner
- & Peter G. Speck
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| Open AccessStructure–activity relationships for the G-quadruplex-targeting experimental drug QN-302 and two analogues probed with comparative transcriptome profiling and molecular modeling
- Ahmed Abdullah Ahmed
- , Shuang Chen
- & Stephen Neidle
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| Open AccessSynthesis, molecular docking and DFT analysis of novel bis-Schiff base derivatives with thiobarbituric acid for α-glucosidase inhibition assessment
- Saba Gul
- , Faheem Jan
- & Li Bo
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| Open AccessFacilitating long-term cell examinations and time-lapse recordings in cell biology research with CO2 mini-incubators
- Ali Talebipour
- , Mehrdad Saviz
- & Reza Faraji-Dana
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| Open AccessDevelopment of tight junction-strengthening compounds using a high-throughput screening system to evaluate cell surface-localized claudin-1 in keratinocytes
- Hiroki Sakamoto
- , Momoyo Nishikawa
- & Seigo Yamada
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| Open AccessIdentification of potential inhibitor against Leishmania donovani mitochondrial DNA primase through in-silico and in vitro drug repurposing approaches
- Mitul Nath
- , Deep Bhowmik
- & Diwakar Kumar
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| Open AccessIndole-3-carbinol (I3C) reduces apoptosis and improves neurological function after cerebral ischemia–reperfusion injury by modulating microglia inflammation
- Long Peng
- , Xingjia Zhu
- & Peipei Gong
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| Open AccessPsychedelics and sexual functioning: a mixed-methods study
- Tommaso Barba
- , Hannes Kettner
- & Bruna Giribaldi
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| Open AccessFunctional brain responses to emotional faces after three to five weeks of intake of escitalopram in healthy individuals: a double-blind, placebo-controlled randomised study
- Sophia Armand
- , Christelle Langley
- & Patrick MacDonald Fisher
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| Open AccessMetabolite profiling and in-silico studies show multiple effects of insecticidal actinobacterium on Spodoptera littoralis
- Mohamed Khaled Diab
- , Hala Mohamed Mead
- & Sahar Ahmed El-Shatoury
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| Open AccessTargeting the receptor binding domain and heparan sulfate binding for antiviral drug development against SARS-CoV-2 variants
- Zi-Sin Yang
- , Tzong-Shiun Li
- & Ching-Ming Chien
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| Open AccessRegulation of the antibiotic elution profile from tricalcium phosphate bone cement by addition of bioactive glass
- H. K. Abd El-Hamid
- , Mohammad M. Farag
- & R. L. Elwan
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| Open AccessKnockdown of Hyaluronan synthase 2 suppresses liver fibrosis in mice via induction of transcriptomic changes similar to 4MU treatment
- Noreen Halimani
- , Mikhail Nesterchuk
- & Yuri V. Kotelevtsev
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| Open AccessIntegrating transcriptomics and metabolomics to elucidate the mechanism by which taurine protects against DOX-induced depression
- Yanan Li
- , Luxi Li
- & Pei Jiang
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| Open AccessA comparative study on vildagliptin brand and its generic equivalents using dissolution test as quality control measure tool
- Ghadah H. Altoum
- , Fouza K. AL-Enazi
- & Naif Alenzi
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| Open AccessA Bronze Age lip-paint from southeastern Iran
- Nasir Eskandari
- , Eugenio De Carlo
- & Massimo Vidale
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| Open AccessNovel pyridine bearing pentose moiety-based anticancer agents: design, synthesis, radioiodination and bioassessments
- Marwa M. Mehany
- , Olfat A. Hammam
- & Kurls E. Anwer
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| Open AccessMolecular modelling of fullerene C60 functionalized by nitric oxide for use in biological environment
- Omid Moztarzadeh
- , Morteza Jamshidi
- & Vaclav Babuska
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| Open AccessAerosolized delivery of ESKAPE pathogens for murine pneumonia models
- Katharina Rox
- & Eva Medina
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| Open AccessMycosynthesis of selenium nanoparticles using Penicillium tardochrysogenum as a therapeutic agent and their combination with infrared irradiation against Ehrlich carcinoma
- Abeer I. M. EL-Sayed
- , Mostafa M. El-Sheekh
- & Sahar E. Abo-Neima
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| Open AccessA scalable platform for efficient CRISPR-Cas9 chemical-genetic screens of DNA damage-inducing compounds
- Kevin Lin
- , Ya-Chu Chang
- & Chad L. Myers
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| Open AccessInfluence of copper(I) nicotinate complex on the Notch1 signaling pathway in triple negative breast cancer cell lines
- Mohamed A. Abdel-Mohsen
- , Asmaa M. Badawy
- & Shymaa Abdullah Mohamed
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| Open AccessIntegrated blood and organ profile analysis to evaluate ameliorative effects of kaempferol on 5-fluorouracil-induced toxicity
- Abhilasha Sharma
- , Mehul R. Chorawala
- & Neeta Shrivastava
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| Open AccessHarnessing machine learning to find synergistic combinations for FDA-approved cancer drugs
- Tarek Abd El-Hafeez
- , Mahmoud Y. Shams
- & Aboul Ella Hassanien
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| Open AccessIn vitro and in vivo anti-colorectal cancer effect of the newly synthesized sericin/propolis/fluorouracil nanoplatform through modulation of PI3K/AKT/mTOR pathway
- Shaimaa E. Diab
- , Nourhan A. Tayea
- & Zakia A. Olama
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| Open AccessExploring the apoptotic effects of sericin on HCT116 cells through comprehensive nanostring transcriptomics and proteomics analysis
- Siriluk Ratanabunyong
- , Jeeraprapa Siriwaseree
- & Pornanong Aramwit
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| Open AccessCharacterization of CD90/Thy-1 as a crucial molecular signature for myogenic differentiation in human urine-derived cells through single-cell RNA sequencing
- Katsuhiko Kunitake
- , Norio Motohashi
- & Yoshitsugu Aoki
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| Open AccessA novel anoikis-related gene signature predicts prognosis in patients with sepsis and reveals immune infiltration
- Yonghua Wang
- , Yanqi Chi
- & Shuping Li
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| Open AccessKv3.4 regulates cell migration and invasion through TGF-β-induced epithelial–mesenchymal transition in A549 cells
- Hun Ju Sim
- , Mi Ri Kim
- & So Yeong Lee
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| Open AccessImmunoinformatics approaches in developing a novel multi-epitope chimeric vaccine protective against Saprolegnia parasitica
- Abhigyan Choudhury
- , Pawan Kumar
- & Mohammed Bourhia
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| Open AccessPotential impact on using aspirin as the primary prevention of adverse pregnancy outcomes in twins conceived using ART
- Dongni Huang
- , Yao Xie
- & Xin Luo